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ALS is characterized by the degeneration of upper and lower motor neurons. In about 70% of patients with ALS the disease has an spinal onset, while about 30% of the patients have a bulbar onset. Cognitive dysfunction and behavioral changes are seen in about 50% of the patients, and 15% develop frontotemporal dementia. There is no single test that provides the ALS diagnosis. The diagnosis is base
Huntington's disease is an autosomal dominant neurodegenerative disease that leads to premature death. The disease is caused by a pathological CAG triplet expansion in the huntingtin gene. The disease is most common in Western populations, with onset in middle age and causing progressive motor, cognitive, and psychiatric symptoms. Currently, only symptomatic treatment is provided, but new molecula
This chapter examines mobilisation around sexuality and gender identity in Southeast Asia through an examination of how the lesbian, gay, bisexual, and transgender (LGBT) movement in Vietnam has pursued full recognition and equal rights for all, regardless of sexuality and gender. As the chapter details, the Vietnamese LGBT movement is composed of informal activist groups and networks as well as f
This article reports a Swedish research project designed to study the impact of a cyclic light system, sound absorbents, and selected interior design changes in rooms within an intensive care unit. The authors describe the limitations of many previously reported intensive care unit (ICU) design research projects, and believe that much more knowledge is needed, which reflects a multidisciplinary pe
Antalet asylsökande som undantas från flyktingkonventionens skydd ökar ständigt i Sverige. Leyla Belle Drake och Amin Parsa tar sig an fallet med den 69-årige afghanske mannen som nekats asyl på grund av misstankar om folkrättsbrott i Afghanistan under 80-talet, och finner en skärningspunkt mellan flyktingrätten och straffrätten. Är det i själva verket inkluderingen av de andra i en mänsklighet so
Introduction: Arthroscopic partial meniscectomy (APM) after degenerative meniscus tears is one of the most frequently performed surgeries in orthopaedics. Although several randomised controlled trials (RCTs) have been published that showed no clear benefit compared with sham treatment or non-surgical treatment, the incidence of APM remains high. The common perception by most orthopaedic surgeons i
Background: Ovarian cancer (OC) is usually detected in late clinical stages, and imaging at diagnosis is crucial. Peritoneal carcinomatosis (PC) and cardio phrenic lymph nodes (CPLN) are pathological findings of computed tomography (CT) and are relevant for surgical planning. Furthermore, mammographic breast density (BD) has shown an association with OC risk and might be prognostically relevant. H
When a biomaterial is inserted into the body, proteins rapidly adsorb onto its surface, creating a conditioning protein film that functions as a link between the implant and adhering cells. Depending on the nano-roughness of the surface, proteins will adsorb in different amounts, with different conformations and orientations, possibly affecting the subsequent attachment of cells to the surface. Th
Objective: We aimed to assess the patient experience of informed consent (IC) during acute myocardial infarction (AMI) in a sub-study of the VALIDATE-SWEDEHEART trial. The original trial compared two anticoagulant agents in patients undergoing coronary intervention. A witnessed oral IC was required prior to randomization in patients with ST-segment elevation myocardial infarction, which was subseq
Background: Breastfeeding provides health benefits to both women and children. The rationale behind an individual woman's decision to breastfeed or not can depend on several factors, either independently or in combination. The aim of the current study was to explore attitudes towards breastfeeding among pregnant women in Sweden who intend to breastfeed. Methods: Eleven mothers-to-be, one of whom h
BACKGROUND: Continuity models of midwifery care are rare in Sweden, despite its well-known positive effects. The aim was to describe pregnancy and birth outcome in women participating in a continuity of care project in a rural area of Sweden.METHOD: A register-based study of 266 women recruited to the project and a control group of 125 women from the same catchment area. Midwives provided antenata
OBJECTIVE: Although fear of birth is common during pregnancy and childbirth, the best treatment for fear of birth in clinical care remain unclear. Strong evidence suggests that continuity models of midwifery care can benefit women and birth outcomes, though such models are rare in Sweden. Because women with fear of birth could benefit from such models, the aim of this qualitative study was to exam
