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Kindling is an animal model of epilepsy in which repeated electrical stimulations lead to progressive and permanent amplification of seizure activity, culminating in generalized convulsions. Each brief period of seizure activity during kindling epileptogenesis causes a marked, transient increase of the synthesis of brain-derived neurotrophic factor (BDNF) in cortical and hippocampal neurons. We fi
The solubility of 1,8-cineole, alpha-pinene, limonene, their mixtures and the extract of eucalyptus leaf oils in supercritical carbon dioxide were determined using the dynamic method at 80, 100, 150, and 250 bar and 40 and 60 degreesC for each pressure. The results showed an increase in the solubility of all oils with an increase in pressure and a decrease with temperature. The mixtures of both pu
We measured the optical properties on samples of rat liver tissue before and after laser-induced thermotherapy performed in vivo with Nd:YAG laser irradiation. This made it possible to monitor not only the influence of coagulation on the scattering properties but also the influence of damages to vessels and heat-induced damage to blood on the absorption properties. An experimental integrating-sphe
The origins and spread of eastern Mediterranean civilizations 4000-2000 years ago constitute defining events in human development. Interregional connections across the sea played critical roles in building increasingly sophisticated economies and societies. Research of trade and exchange among these first centers has relied upon ancient societies' archaeological artifacts. The most ubiquitous arti
Objective: to conceptualise mothers’ and fathers’ thoughts and feelings before, during and after the routine ultrasound examination during the second trimester of pregnancy. Design, setting and participants: a grounded theory study. Two to four weeks after their ultrasound examination, 22 Swedish mothers and 22 fathers were interviewed in their homes. Findings: the basic social process was co
During revision total hip replacement using morcellised compacted bone allograft, 16 patients were randomised to receive a graft which had been rinsed in either an ibandronate solution or in saline. Patients were assessed by dual energy x-ray absorptiometry after operation and at 3, 6, 12 and 24 months. A region of interest between the tip of the femoral stem and the distal plastic plug was chosen
PURPOSE: To study whether diabetes could influence glial cells, retinal neurons, and pigment epithelial cells and if so, to evaluate whether any changes could be influenced by aminoguanidine (AG) or probucol (PB). METHODS: Streptozocin (STZ)-induced diabetic male Wistar rats and age-matched control rats were fed a normal diet, addition of AG in the drinking water (0.5 g/l for diabetic and 1.0 g/l
Forest leaf area index (LAI), is an important variable in carbon balance models. However, understory vegetation is a recognized problem that limits the accuracy of sate I lite-estimated forest LAI. A canopy reflectance model was used to investigate the impact of the understory vegetation on LAI estimated from reflectance values estimated from satellite sensor data. Reflectance spectra were produce
Electrical geophysical surveys in the mode of vertical electrical soundings (VES) and continuous vertical electrical soundings (CVES) were conducted in the Leon-Chinandega plains, northwestern Nicaragua, in order to obtain detailed information about the geometry of the different hydrogeological layers in the aquifer and depth to the basement. A total of 51 VES were carried out within the plains. T
An extensive body of literature exists on the obstacles that have to be overcome in green power retailing. In this article, target group-specific marketing is evaluated as a strategy to increase the share of residential customers of green power. A sample of students in the city of Freiburg, Germany was interviewed in order to assess their awareness of environmental issues, their willingness to cha
Background and purpose: To evaluate the efficacy and safety of boron neutron capture therapy (BNCT) for glioblastoma multiforme (GBM) using a novel protocol for the boronophenylalanine-fructose (BPA-F) infusion. Patient and methods: This phase II study included 30 patients, 26-69 years old, with a good performance status of which 27 have undergone debulking surgery. BPA-F (900 mg BPA/kg body weigh
Objective Short bowel syndrome patients frequently experience impaired health-related quality of life. This syndrome is also associated with increased costs for the individuals concerned and the community. Intake of specially processed cereals has been demonstrated to decrease intestinal secretion. This study evaluates the effect of a supplementary diet with specially processed cereals compared wi
PID controller design is considered where optimal controllerparametersare found with constraint on maximum sensitivity and robustness withregard to a cone bounded static nonlinearity acting in feedback withpart of the plant. Thedesign procedure has been successfully applied in the synthesis of acontroller for an Anti-lock Braking System (ABS).
BACKGROUND: Several of the known risk factors for ovarian cancer are thought to act through their effects on ovulation and the menstrual cycle, such as parity, breastfeeding, and use of oral contraceptives. We aimed to assess the effect of these three risk factors, and of tubal ligation, on the risk of ovarian cancer in women who carry a mutation in the BRCA1 or BRCA2 genes. METHODS: We did a matc
Isolated segments (1-2 mm) of small subcutaneous arteries (diameter 0.1-0.9 mm) and veins (0.1-1.0 mm) from patients with hypertension (essential n = 13, renovascular n = 6) and controls (n = 17) were examined. The relaxant responses to the sensory transmitters calcitonin gene-related peptide (CGRP) and substance P, and the contractile responses to potassium and noradrenaline were studied. Enhance
Objective: (1) To evaluate constraint-induced movement therapy for chronic stroke patients modified into group practice to limit the demand on therapist resources. (2) To explore whether extended mitt use alone may enhance outcome. Design: A combined case-control and randomized controlled study with pre- and post-treatment measures by blinded observers. Setting: A university hospital rehabilitatio
To investigate the molecular mechanisms of the quantitative factor V (FV) deficiency associated with the FV R2 haplotype, 4 missense mutations, Met385Thr, His1299Arg, Met1736Val, and Asp2194Gly, identified in the R2 haplotype allele, were analyzed by in vitro expression studies. The FV variant carrying all 4 mutations showed a markedly lower steady-state expression level than wild-type FV because
A quantum coherent capacitor subject to large amplitude pulse cycles can be made to emit or reabsorb an electron in each half cycle. Quantized currents with pulse cycles in the GHz range have been demonstrated experimentally. We develop a nonlinear dynamical scattering theory for arbitrary pulses to describe the properties of this very fast single electron source. Using our theory we analyze the a
The intrinsic spin Hall effect on spin accumulation and electric conductance in a diffusive regime of a 2D electron gas has been studied for a 2D strip of a finite width. It is shown that the spin polarization near the flanks of the strip, as well as the electric current in the longitudinal direction, exhibit damped oscillations as a function of the width and strength of the Dresselhaus spin-orbit
