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Inflammation researcher Ben King studies the function of two different proteins in connection with diabetes. In the future, such knowledge may be important for the development of new treatments for people with diabetes. Ben King is this year’s recipient of the Medeon Award for his innovative research. “I was very surprised and feel very honored to receive the award. In my role, I do a lot of exper

https://www.ludc.lu.se/article/award-protein-research-may-lead-new-treatments-diabetes - 2025-11-30

We would like to congratulate six researchers at Lund University Diabetes Centre, who have been awarded research grants within medicine and health by the Swedish Research Council (VR). The six researchers are affiliated with Excellence of Diabetes Research in Sweden (EXODIAB), which is a strategic research area within diabetes at Lund University.Helena Elding Larsson, professor of autoimmune disea

https://www.ludc.lu.se/article/six-ludc-researchers-receive-medicine-and-health-grants-vr - 2025-11-30

An international team of researchers has investigated whether oral insulin can prevent early signs of type 1 diabetes and clinical diagnosis in children with an increased risk of developing the disease. Although treatment with oral insulin could not prevent development of diabetes-related autoantibodies, oral insulin delayed the rate of disease progression in children who developed such autoantibo

https://www.ludc.lu.se/article/oral-insulin-delayed-onset-type-1-diabetes-some-children-increased-risk-disease - 2025-11-30

Social and economic factors have led to a dramatic rise in type 2 diabetes and obesity around the world. In a review in Science, Mark McCarthy, professor at the University of Oxford, UK, and Paul Franks, professor at Lund University, Sweden, examine the knowledge of the actual causes and the interplay between genetics and lifestyle factors. By studying how our genes express themselves in response

https://www.ludc.lu.se/article/review-type-2-diabetes-and-obesity-what-do-we-really-know - 2025-11-30

Diabetes researchers at Lund University have previously shown that people with diabetes can be stratified into five subgroups with differing disease progression. A new study by the same researchers provides increased evidence for the clinical relevance of the classification system. The researchers also present new findings of significant differences between subgroups in the development of complica

https://www.ludc.lu.se/article/new-research-classification-diabetes-identifies-high-risk-group - 2025-11-30

How can a tiny genetic change alter the body´s sugar balance? At Lund University, researchers have used stem cells to create two versions of the same cell – one carrying the genetic variant and one without – to see how melatonin affects insulin-producing cells and contributes to development of type 2 diabetes. Study summarySkin cells from a person carrying a risk gene for type 2 diabetes were “rep

https://www.ludc.lu.se/article/stem-cell-technology-reveals-new-insights-melatonin-and-diabetes - 2025-11-30

DIABETES. After more than a decade of stagnation, there is a major surge in kidney research effort. New drugs and biomarkers make it possible to detect and slow the progression of the disease earlier – something that long seemed unattainable. This will impact people with diabetes, for whom kidney damage is a serious long-term complication. “We are entering a new era. What is happening now is simil

https://www.ludc.lu.se/article/hope-kidney-care - 2025-11-30

Lund University Diabetes Centre has entered into a collaboration with the Regeneron Genetics Center LLC (RGC) and the University of Helsinki involving exome-sequencing and whole genome array genotyping of greater than 9,000 individuals. The collaboration will involve the largest sequencing study in diabetes families to date and aims to help generate knowledge about how to predict diabetes, causes

https://www.ludc.lu.se/article/lund-initiates-genetic-sequencing-study-diabetes-families-provide-new-insights-what-causes-disease - 2025-11-30

Research from Lund University in Sweden can explain why type 2 diabetes is inherited to a greater extent from an individual’s mother. The heredity of a previously known risk gene, THADA, has proven to be dominant if it comes from the mother, whereas it has little or no effect on the child’s risk of disease if it originates from the father.
“Our research contributes to increased knowledge about the

https://www.ludc.lu.se/article/thada-new-findings-role-mother-type-2-diabetes - 2025-11-30

A new experimental and clinical study from Lund University in Sweden shows that the sleep hormone melatonin impairs insulin secretion in people with a common gene variant.

“This could explain why the risk of type 2 diabetes is greater among, for instance, overnight workers or people with sleeping disorders”, says Professor Hindrik Mulder who is responsible for the study. Melatonin is a naturally

https://www.ludc.lu.se/article/new-findings-explain-connection-between-melatonin-and-type-2-diabetes - 2025-11-30

One in three people with diabetes will face some form of renal impairment in the course of their lives. Studies conducted by researchers at the Lund University Diabetes Centre may lead to the development of an entirely new principle for treating type 2 diabetes and preventing kidney damage in the future. Previous analyses have not been able to identify genetic causes as to why some people have a h

https://www.ludc.lu.se/article/new-findings-can-lead-new-principle-treating-diabetic-kidney-damage - 2025-11-30

One in three people with diabetes will face some form of renal impairment in the course of their lives. Studies conducted by researchers at the Lund University Diabetes Centre may lead to the development of an entirely new principle for treating type 2 diabetes and preventing kidney damage in the future. Previous analyses have not been able to identify genetic causes as to why some people have a h

https://www.ludc.lu.se/article/new-findings-can-lead-new-principle-treating-diabetic-kidney-damage-0 - 2025-11-30

The European Research Council makes a large investment in diabetes research. A project led by Professor Paul Franks at Lund University Diabetes Centre is to develop methods that can be used in the design of preventive treatment for type 2 diabetes and cardiovascular disease. - Through this project we will use functional genomics and epidemiology to identify novel molecular mechanisms that underlie

https://www.ludc.lu.se/article/focus-personalized-treatment-type-2-diabetes-and-cardiovascular-disease - 2025-11-30

Social and economic factors have led to a dramatic rise in type 2 diabetes and obesity around the world. In a review in Science, Mark McCarthy, professor at the University of Oxford, UK, and Paul Franks, professor at Lund University, Sweden, examine the knowledge of the actual causes and the interplay between genetics and lifestyle factors. By studying how our genes express themselves in response

https://www.ludc.lu.se/article/type-2-diabetes-and-obesity-what-do-we-really-know - 2025-11-30

Obesity is associated with reduced muscle mass and impaired metabolism. Epigenetic changes that affect the formation of new muscle cells may be a contributing factor, according to new research from Lund University, Sweden. In a new study, doctoral student Cajsa Davegårdh has studied so-called DNA methylation in muscle stem cells in both obese and non-obese individuals. DNA methylation is an epigen

https://www.ludc.lu.se/article/obesity-reprogrammes-muscle-stem-cells - 2025-11-30

BEAt-DKD (“Biomarker Enterprise to Attack Diabetic Kidney Disease”), a unique public private partnership funded by the Innovative Medicines Initiative (IMI), member companies from the European Federation of Pharmaceutical Industries and Associations (EFPIA), the Juvenile Diabetes Research Foundation (JDRF) and the state of Switzerland has announced the launch of a 5-¬¬year project (total budget 28

https://www.ludc.lu.se/article/innovative-medicines-initiative-project-precision-medicine-dkd - 2025-11-30

Almost 0.5 billion people have diabetes globally, many of whom are unaware of their condition; within the next two decades, this number is expected to double, largely owing to a growing, ageing, and increasingly industrialized global population. Lund University receives 100 million SEK from The Swedish Foundation of Strategic Research to help stop this development. “This is excellent news and a fa

https://www.ludc.lu.se/article/100-million-sek-personalized-medicine-diabetes - 2025-11-30

Throughout our lives, our genes are affected by the way we live. Diet, exercise, age and diseases create imprints that are stored in something called methylome. Now, for the first time, researchers at the Lund University Diabetes Centre in Sweden have been able to map the entire methylome in the pancreatic islets which produce insulin, and the researchers have made several important discoveries. U

https://www.ludc.lu.se/article/unique-mapping-methylome-insulin-producing-islets - 2025-11-30

Six researchers from Lund University Diabetes Centre have recieved prestigous grants from the European Research Council (ERC). In order to celebrate the success we invited the public to an open seminar. Some of the talks can be reviewed here (in Swedish). Forskning för bättre folkhälsa:Framsteg inom typ 2-diabetes, fetma och hjärtsjukdomar   Professor Olle Melander: Hormoner – gårdagens livräddare

https://www.ludc.lu.se/article/successful-research-funded-european-research-council - 2025-11-30

They govern everything we think and do, they give us the ability to feel pain and to secrete insulin: they are the ion channels that are present in every one of our cells and that control the electrical impulses in our nerve and muscle cells. “For me, they are the very spark of life”, says Dame Frances Ashcroft, professor at the University of Oxford, who is also now to be an honorary doctor at Lun

https://www.ludc.lu.se/article/injections-pills-research-neonatal-diabetes - 2025-11-30