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C1INH (C1-inhibitor) is a multifunctional SERPIN (serine protease inhibitor) that functions as a major negative regulator of the complement, coagulation, and kallikrein-kinin systems. C1INH products were originally developed for the treatment of hereditary angioedema associated with C1INH deficiency. A growing body of literature indicates that C1INH products may find utility in the management of s
Based on a combination of morphometric analyses, a chloroplast DNA phylogeny, and multivariate analyses of whole genome sequence data from >300 museum samples, we discuss and evaluate the delimitation, taxonomy, and evolution of wild and escaped taxa in Mentha subgen. Mentha, focusing on the northern hemisphere. Thirteen species (Mentha aquatica, M. arvensis, M. australis, M. capensis, M. dahurica
Very-low-field MRI (<100 mT) holds promise for Point-of-Care brain imaging applications, including stroke and multiple sclerosis, with T1 mapping emerging as a key biomarker for brain development and pathology. However, current low-field T1 mapping protocols suffer from long acquisition times and limited multi-site repeatability. This study aimed to improve T1 mapping at 64 mT using a clinically f
In this chapter we share, reflect and learn from the findings of a long-standing collaboration between two teacher educators who have been working together on the topic of refugee education since 2016. Based in Sweden and England, the two researchers have over that time reflected on the changing educational and political discourse which permeates the contexts in which they work. In this chapter, w
This experimental study explored how adopting a deceptive stance affects linguistic processes during real-time production of multi-sentence texts in speaking and writing. Language production involves planning, monitoring and editing – processes that give rise to and are shaped by fluctuations in processing demands. Deception is assumed to influence these processes as speakers and writers manage co
We study correlations in the prepare-and-measure scenario when quantum communication is constrained by photon-number statistics. Such constraints are natural and practical control parameters for semi-device-independent certification in optical platforms. To analyse these scenarios, we show how semidefinite programming relaxations for noncommutative polynomial optimization can be used to bound the
The HIBEAM-NNBAR program is a proposed two-stage experiment at the European Spallation Source focusing on searches for baryon number violation processes as well as ultralight dark matter. This paper presents recent advancements in computing and simulation, including machine learning for event selection, fast parametric simulations for detector studies, and detailed modeling of the time projection
Mantle cell lymphoma (MCL) is a relatively rare B-cell lymphoma subtype, with a higher incidence among males and a median age of 70 years at diagnosis. MCL is characterized by clinically diverse behavior, from indolent disease to extremely aggressive, related to the presence of biological risk factors such as proliferation rate and TP53 mutations. Most often, patients present with disseminated dis
The Special Section on Post-growth food systems for a just social-ecological transition within planetary boundaries explores post-growth and degrowth approaches that advocate for sufficiency, care, regeneration, and the democratization of food systems. It shows that post-growth food initiatives face multiple structural barriers, including capitalist systems that prioritize profit over ecological a
Purpose: To verify the accuracy of clinically used cardiac MRI T1 mapping sequences for measuring extracellular volume fraction (ECV) throughout the spectrum of pathologic values using an independent reference standard. Materials and Methods: Acute myocardial ischemia was induced in six pigs using endovascular balloon occlusion in the left anterior descending artery between October 2018 and Novemb
Background: Patients with hemophilia are reported to have a high prevalence of established and potential risk factors for kidney dysfunction and damage. However, comprehensive studies specifically evaluating kidney function in hemophilia, particularly hemophilia B (HB), are limited, with most research focusing on hemophilia A. Objectives: This study aimed to assess markers of glomerular filtration
This chapter examines the relationship between the diversity of membership and features of Collaborative Work Spaces (CWS) and the growth of regional entrepreneurship. CWS have grown remarkably over the past decades and, alongside a suite of other forums for interaction between entrepreneurial actors (such as meetups and accelerators), have become notable features of entrepreneurial ecosystems. CW
For quite some time, research across various fields has highlighted diversity as a critical factor in fostering creativity, knowledge generation, innovation, and entrepreneurship-at the levels of organizations, cities, regions, and entire countries. The aim of this book is to provide a comprehensive overview of the role of diversity in modern advanced economies, appealing to academics, researchers
INTRODUCTION: Alzheimer's disease (AD) diagnosis has been based largely on clinical symptoms, despite their limited sensitivity and specificity. Biomarker use was proposed to support a more accurate and timely diagnosis. However, neuroimaging or cerebrospinal fluid (CSF) is rarely used in primary care due to their perceived invasiveness, cost, and need for appropriate infrastructure. Blood-based b
Objectives There is a lack of knowledge about whether occupational exposures increase the risk of emphysema, especially in never-smokers. Our objective was to determine if occupational exposures are associated with emphysema and impaired diffusing capacity. Methods In the Swedish CArdioPulmonary bioImage Study (SCAPIS), persons from the general population aged 50–64 answered a questionnaire and un
