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How often did the Sava River flood in the past? A sedimentological and chronological investigation of terrace overbank sediments, Šabac (Serbia)
In this study, we investigated overbank sediments of the first terrace of Sava river in Šabac, exposed at a residential building construction site. Sediment characteristics such as grain size, magnetic susceptibility, chemical composition, and loss on ignition (LOI) at 550 °C and 950 °C were determined at 5 cm resolution, accompanied by visual inspection to assess color, pedogenic structure, and o
Anchoring and subjective belief distributions
We investigate how the anchoring effect—a well-established cognitive bias—influences subjective belief distributions. While prior research extensively examines the impact of anchoring and other biases on point estimates, their effect on the underlying distribution and its higher moments remains unexplored. Using two pre-registered online experiments (N = 1467) and two elicitation methods, we find
Providing students with a compass to navigate: teaching political economy to human geography students
Despite the centrality of economic theories (including political economic theories) in human geographic research, there is a massive shortage of courses covering this topic in many human geography departments. In this paper, we use the example of a third-semester elective MSc course in political economic theory designed for students in human geography to contribute to this point. The course aims t
Accessing the proteome of extracellular vesicles via rapid acoustic isolation of a minute human blood plasma sample
Background: Despite substantial progress in the field of mass spectrometry, there remain barriers to measuring the extracellular vesicles (EVs) proteome in blood plasma. Recent work has shown that isolating EVs can make it possible to detect proteins that have low abundance in plasma. Commonly used EV isolation methods either require large sample volumes and long ultracentrifugation times, or else
System-wide assessment of Indonesia's plastic value chain : Mapping flows and stakeholders dynamics
Indonesia faces a severe plastic pollution crisis driven by extensive plastic usage and inadequate waste management. To effectively address this issue and promote sustainable circularity, it is crucial to understand the dynamics of plastic production, use, and end-of-life management, as well as the interactions among stakeholders throughout the plastics lifecycle. Without such a comprehensive unde
Fermi surface and pseudogap in highly doped Sr2IrO4
The fate of the Fermi surface in bulk electron-doped Sr2IrO4 remains elusive, as does the origin and extension of its pseudogap phase. Here, we use high-resolution angle-resolved photoelectron spectroscopy (ARPES) to investigate the electronic structure of Sr2−xLaxIrO4 up to x = 0.2, a factor of two higher than in previous work. We find that the antinodal pseudogap persists up to the highest dopin
Mobility data for reduced uncertainties in model-based WWTP design
Model-based design is an emerging tool for dealing with the uncertain dynamic loads entering wastewater treatment plants (WWTPs). But our understanding about the load-driving population-dynamics is limited. Therefore, we studied if mobility data (mobile telecommunications data) could be used to reduce uncertainties during design. Mobility data from Uppsala, Sweden between 2019–2022 clearly quantif
Occupational exposure to chemicals and particles and incidence of myocardial infarction—a nationwide cohort study in Sweden
Cardiovascular disease (CVD) is the leading cause of death in Europe, with myocardial infarction (MI) being one of its most severe manifestations. While many risk factors for CVD are well known, occupational exposures remain relatively understudied—especially in analyses that adjust for co-occurring workplace exposures. This study aimed to examine the association between occupational exposure to c
Pharmacological inhibition of JNK-MAPK disrupts cigarette smoke-induced RUNX2/Galectin-3 -driven EMT and cancer stemness in lung adenocarcinoma cells
Cigarette smoke (CS), a major driver of lung cancer (LC), promotes epithelial-mesenchymal transition (EMT) and stemness resulting in metastasis, therapy resistance, and recurrence, but the precise mechanism is elusive. Building on our earlier identification of Runt related transcription factor-2 (RUNX2) and Galectin-3 (Gal-3) as mediators of CS-induced EMT, in this study, we aimed to identify a po
Impact of neoadjuvant therapy on short-term outcomes after left pancreatectomy : A propensity score–matched international multicenter study
Background: Neoadjuvant therapy is protective of postoperative pancreatic fistula in pancreatoduodenectomy. However, the effect of neoadjuvant therapy after left pancreatectomy remains unclear. The aim of this international multicenter study was to evaluate the impact of neoadjuvant therapy on short term outcomes after left pancreatectomy for pancreatic ductal adenocarcinoma. Methods: Patients und
The Two-Dimensional Coulomb Gas : Fluctuations Through a Spectral Gap
We study a class of radially symmetric Coulomb gas ensembles at inverse temperature β=2, for which the droplet consists of a number of concentric annuli, having at least one bounded “gap” G, i.e., a connected component of the complement of the droplet, which disconnects the droplet. Let n be the total number of particles. Among other things, we deduce fine asymptotics as n→∞ for the edge density a
Abandoning Theology for Theory : Stephen D. Moore, Gilles Deleuze, and the Secularization of Biblical Studies
Det är inne att se trött ut – men det funkar bara på pigga 20-åringar
J. Taylor - Sexism in the City: Women Stockbrokers in Modern Britain
Raman microspectroscopic analysis of the tissue-specific composition of the human osteochondral junction in osteoarthritis : A pilot study
This study investigates the influence of osteoarthritis (OA) disease severity on the bio-composition of the osteochondral junction at the human tibial plateau using Raman microspectroscopy. We specifically aim to analyze the spatial composition of mineralized osteochondral tissues, i.e., calcified cartilage (CC) and subchondral bone plate (SBP) from unfixed, hydrated specimens. We hypothesize that
Increased mitochondrial fusion via systemic OPA1 overexpression promotes dyslipidemia and atherosclerosis in LDLR deficient mice
Objective: Mitochondria are involved in cellular metabolism, energy production, calcium homeostasis, and the synthesis of sterols and bile acids (BAs). Emerging evidence suggests that mitochondrial dynamics including biogenesis, fusion, fission, and mitophagy critically influence cardiometabolic diseases, yet their role in atherogenesis remain poorly understood. Mitochondrial fusion ensures metabo
Paleolithic diet fraction and score in post hoc data analysis of a randomized controlled trial with lifestyle interventions for abdominal obesity
Background: Paleolithic Diet Fraction (PDF) and Paleolithic Diet Score (PDS) are both measures of how closely a food intake conforms to a Paleolithic dietary pattern. PDF is calculated directly from an individual’s absolute food intake and PDS is an aggregated score based on an individual’s food intake relative to a population. Both are inversely associated with all-cause and cause-specific mortal
