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This study aimed to examine the significance that a low-threshold meeting place has on everyday life, the well-being, and possible experiences of loneliness of the socially vulnerable people who visit it regularly. We used McMillan & Chavis’s theory about sense of community as a theoretical framework for our study. To gather data for the study, we conducted qualitative interviews with individu
The increasing demand for efficient neural network (NN) inference on edge devices has driven the need for hardware-level optimizations that balance computational accuracy with energy and area efficiency. This thesis explores the design and implementation of a dynamic approximate multiplier capable of mixed-precision inference, focusing on floating-point (FP) formats. Using a logarithmic-approximat
This discussion paper recognizes that the Glasgow Consensus Statement is not optimally useful unless it is disseminated widely. Knowledge and use of the consensus statement and its call for centering humanism in healthcare extend to medical and health organizations and groups beyond the International Conference on Communication in Healthcare and Patient Education and Counseling audiences, to profe
Background: Asthma with low levels of type 2 (T2) biomarkers is poorly understood. Objective: To characterize severe asthma phenotypes and compare changes in asthma outcomes from pre- to postbiologic treatment along a gradient of T2 involvement. Methods: This was a registry-based cohort study including data from 24 countries. Biomarker distribution (blood eosinophil count, fractional exhaled nitri
BACKGROUND: Neurointensive care is moving toward more automated patient management. This study aimed to evaluate a novel external ventricular drainage (EVD) system, the VGuard® system, as a tool for intracranial pressure (ICP) monitoring and automating ventricular drainage of cerebrospinal fluid (CSF), focusing on its safety and potential to reduce complications associated with manual EVD manageme
Blink characteristics such as duration, amplitude, and eyelid velocity are widely used indicators of cognitive and physiological states. While early magnetic search coil studies suggested that vertical eye orientation relative to the head influences blink measurements, subsequent research has largely ignored this factor. No studies have investigated whether vertical eye orientation effects replica
Swedish tragedies from the first half of the eighteenth century often looked at French drama, but there are notable instances where inspiration seems to have come from elsewhere: Erik Wrangel’s Torilla (1738), for example, breaks conventions expected of French theatre by letting princes battle supernatural forces on stage; the story presented in Eric Brander’s Cleopatra (1749) seems familiar from
The Perseverance rover landed in Jezero crater on Mars, which once contained a lake of liquid water. We report the rock properties encountered by Perseverance during a 10-kilometer traverse extending over 400 meters in elevation, from beneath Jezero's western sedimentary fan to the upper crater rim. These rocks consist of coarse-grained olivine, magnesium and iron carbonates, silica, and phyllosil
Objective: In the present study, we investigated the role of the gut–liver crosstalk in the pathogenesis of steatotic liver disease (SLD) induced by the compounding and deleterious effects of alcohol and metabolic risk factors, and explored the potential translational aspects of microbiome-based interventions. Design: The effects of combined exposure to alcohol and a high-fat, high-cholesterol die
The link between regional tau load and clinical manifestation of Alzheimer's disease (AD) highlights the importance of characterizing spatial tau distribution across disease variants. In typical (memory-predominant) AD, the spatial progression of tau pathology mirrors the functional connections from temporal lobe epicentres. However, given the limited spatial heterogeneity of tau in typical AD, at
