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Effective medical education relies on clearly defined learning objectives that foster deep and meaningful learning. This article presents a consensus-driven proposal for national learning objectives in dermatology and venereology within Sweden’s new medical programme qualifying for licensure. The primary aim is to harmonize educational standards across all medical faculties and to establish a comm
Background: The study of emotion regulation (ER) has gained traction in forensic psychological and psychiatric research as a correlate of antisocial and aggressive behavior as well as for its relevance to psychopathology. However, conceptual and definitional ambiguity persists. Methods: This pre-registered systematic review aimed to investigate how ER is conceptualized and measured in forensic pop
IMPORTANCE: Randomized controlled trials (RCTs) in children and adolescents provide evidence for patients, families, researchers, clinicians, regulators, funders, policymakers, and other interest holders to inform decisions about health care interventions and improve outcomes for young patients and their families. To critically evaluate, interpret, and apply trial results, readers require access t
Background: Recent advances have highlighted the potential of artificial intelligence (AI) systems to assist clinicians with administrative and clinical tasks, but concerns regarding biases, lack of regulation, and potential technical issues pose significant challenges. The lack of a clear definition of AI, combined with limited focus on qualitative research exploring clinicians' perspectives, has
BACKGROUND: High-risk neuroblastoma (HR-NB) is associated with therapy-resistant relapse, and novel therapeutic strategies are needed. GSPT1 is a GTPase involved in protein translation whose disruption may offer therapeutic potential in translation-dependent cancers.METHODS: GSPT1 expression was assessed in publicly available clinical data and tissue microarrays. GSPT1-degrading molecular glues we
Nature-based Solutions (NBS) are recognized as key actions for achieving sustainable and resilient development. They are being implemented in a variety of fields, such as urban planning, and offer a wide range of social, environmental, and economic benefits. While there has been a significant increase in the number of NBS practices in recent years, there remains a notable imbalance, with a bias to
Carbon Black (CB), graphene, and nanodiamonds represent three classes of manufactured carbonaceous nanoparticles consisting almost exclusively of insoluble material. Particle-related Reactive Oxygen Species (ROS) have been linked to in vivo and in vitro toxicity and determining particle ROS activity is an efficient way of estimating nanomaterial toxicity and assist in the safe-by-design developmen
IMPORTANCE: Key information is often omitted from pediatric randomized controlled trial (RCT) protocols, including details on dose adjustments of interventions based on age, body surface area, or weight; developmental appropriateness of trial outcome measures and processes; or strategies to minimize participants' anxiety and pain. These deficiencies impair the planning and implementation of potent
Friendship is a common and complex social bond. Among friendship practices yet to be fully understood are group- versus dyadic-oriented friendship styles, or whether people socialize with one versus multiple friends at a time. We report two studies comparing friendship styles and relational mobility among 1674 young adults (18–35 years old) in Japan and the United Kingdom. Respondents from both co
Randomised controlled trial (RCT) protocols contain essential details needed to understand and evaluate the trial's planned aims, design, data collection methods, monitoring, data analysis, and participants' safety. However, key information is often omitted from paediatric RCT protocols, including details on dose adjustments of interventions based on age, body surface area, or weight; developmenta
BACKGROUND: TF (transcription factor) Prdm16 (positive regulatory domain-containing protein 16) regulates hematopoietic and neuronal stem cell homeostasis, adipose differentiation, and cardiac development. Its role in the circulatory system extends beyond the heart, as Prdm16 loss in arterial endothelial cells (ECs) impairs arterial reperfusion of ischemic mouse limbs due to endothelial dysfunctio
The integration of proton exchange membrane fuel cells (PEMFCs) in heavy-duty vehicles and other demanding applications, such as aviation, would be simplified if the stacks could operate above 100 °C instead of the traditional low temperature (LT, up to 80 °C), thereby allowing a reduction in cooling system in size and power. This review offers a comprehensive compilation of experimental studies r
Aim: This study evaluates the health effects of plant-based dairy alternatives in healthy individuals and those with Inflammatory Bowel Disease (IBD). Specifically, it investigates whether replacing one daily meal with a plant-based alternative has a positive impact on intestinal microbiota composition and gut health. It also investigates whether the effect of probiotic bacteria in yogurt depends
