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Background: The prevalence of mental health problems is increasing, placing growing pressure on mental healthservices to provide care that is meaningful, accessible, and supportive for those who require it. However, currentpractices often do not fully meet individuals’ needs for person-centred, recovery-oriented, and integrated care andsupport. As these care and support models are being introduced

Background: PSMA PETs can track treatment response in patients with prostate cancer. Recent integration of the RECIP framework with PROMISE v2 allows quantitative assessment of PSMA PETs. While useful for assessing differentially responding lesions, manual measurement and tracking is cumbersome and PSA reliance can be misleading. We evaluated an automated AI-enabled platform, aPROMISE, for longitu

Determining the prevalence of atmospheres on terrestrial planets is a core objective in exoplanetary science. While M dwarf systems offer a promising opportunity, conclusive observations of terrestrial atmospheres have remained elusive, with many yielding flat transmission spectra. We observe four transits of the hot terrestrial planet TOI-1685 b using James Webb Space Telescope (JWST)’s Near Infr

Introduction: Pre-anaesthesia (PA) assessments aim to ensure that anaesthesia is administered as safely and efficiently as possible, minimising risks and improving patient care. While the goal remains the same, the content, delivery, setup and evaluation of PA assessments have evolved over the years, driven by technological opportunities and healthcare systems' needs. Hence, the objective of this

IntroductionBreast cancer is a heterogeneous disease in which imaging plays a central role. Beyond identifying malignancy, imaging provides information about the mammographic tumor appearance, breast density, and characteristics of the surrounding adipose tissue, which may reflect underlying tumor biology and relate to the prognosis. The aim of this thesis was to explore how features from mammogra

Weight discrimination is the unjust treatment of individuals because of their weight. There have been very few interventions to address weight discrimination, due in part to the lack of consensus on key messages and strategies. The objective of the third Canadian Weight Bias Summit was to review current evidence and move towards consensus on key weight bias and obesity discrimination reduction mes

Weight stigma is rooted in a fundamental misunderstanding of the origins of obesity, wherein the interplay of behavioral, environmental, genetic, and metabolic factors is deemphasized. Instead, the widespread societal and cultural presence of weight stigma fosters misconceptions of obesity being solely a result of unhealthy personal choices. Weight stigma is pervasive in childhood and adolescence

Obesity is a stigmatized disease due to pervasive personal, professional, institutional, and cultural weight bias. Individuals with obesity experience weight bias across their lifespan and settings, which can affect their life chances and significantly impact health and social outcomes. The objectives of this study were to: (a) explore weight bias and stigma experiences of people living with obesi

Background: Many children who have overweight or obesity before puberty can develop obesity in early adulthood, which is associated with increased morbidity and mortality. The preschool years (ages 0-5) represents a point of opportunity for children to be active, develop healthy eating habits, and maintain healthy growth. Surveillance of childhood overweight and obesity in this age group can help

Accurate and early detection of Acute Lymphoblastic Leukemia (ALL) is critical for timely intervention and improved patient outcomes. However, the development of reliable deep learning models for hematological image analysis is challenged by limited data availability, dataset bias, and the need for trustworthy predictions in clinical settings. In this study, we propose a Bayesian deep learning fra

Compared with more sophisticated equilibrium theory, naive, non-equilibrium behavioral rules often better describe individuals’ initial play in games. In addition, in repeated play in games, when individuals have the opportunity to learn about their opponents’ past behavior, learning models of different sophistication levels are successful in explaining how individuals modify their behavior in res

Background: The effects of peri-operative training interventions in connection with oesophageal surgery have not been thoroughly investigated. The aim of this randomised, controlled, single-blind study was to evaluate a peri-operative physical training programme in patients undergoing oesophageal cancer resection surgery due to cancer of the oesophagus or the gastro-oesophageal junction. Methods:

People with obesity commonly face a pervasive, resilient form of social stigma. They are often subject to discrimination in the workplace as well as in educational and healthcare settings. Research indicates that weight stigma can cause physical and psychological harm, and that affected individuals are less likely to receive adequate care. For these reasons, weight stigma damages health, undermine

This review is based on an exploration of the published literature over the past 20 years in the area of weight bias, stigma and discrimination and its association with obesity treatment. National and international obesity organizations have identified obesity stigma as a key barrier to effectively addressing the obesity epidemic and have called for theory driven interventions to reduce it. Both t

Background: Pro-neurotensin (pro-NT) is the stable circulating precursor of neurotensin (NT), a neuropeptide expressed mainly in the central nervous system and small intestine that regulates key physiological processes like fatty acid absorption in the gut and suppresses appetite via central mechanisms. Studies in NT-deficient mice and humans implicate NT in obesity and insulin resistance, highlig

Inter-arm blood pressure differences (IABPDs) can be caused by atherosclerosis. We investigated 29921 men and women aged 50–64years from the nationwide population-based Swedish CArdio Pulmonary bioImage Study (SCAPIS) to evaluate if IABPD is related to risk factors for atherosclerosis and can be used as a marker of atherosclerosis as evaluated by coronary artery calcium score, arterial segment inv