The purpose of this project was to investigate protein stabilization by formulation excipients during the process of freeze-drying using Molecular Dynamics (MD) simulation. A recombinant therapeutic protein, Reteplase, was used as a model and the study focused on a comparative analysis of two excipients, arginine and tranexamic acid (TXA), as included in commercially available formulations of Rete

Cross-national surveys have pointed out that environmental concern has been decreasing across the globe over time due to a focus on economic growth. While cultural and socio- demographic factors determine the degree of a lack of environmental concern, preference measures namely risk, patience, positive reciprocity, negative reciprocity, altruism and trust have found to be determinants as well. Thi

BUT A SURFACE is a product that offers a surface which helps users to switch between positions they like freely when working from home with devices like laptops. Under the COVID-19 pandemic, working from home has become a “new normal”. Compared with working in the office or school, people usually perform more relaxed in positions like sitting casually on lounge chairs or sofas when working from h

The project explores the harmful effects of excessive light exposure at night and people’s sleeping habits. Most people would use electronic devices in bed for a long time before sleep, and sometimes we fall asleep and accidentally leave the light on all night. And there are also some people who are afraid of darkness prefer to sleep with the light on all night. Sleeping with the light on delibe

The connection between general government debt levels and centralization of general government expenditure is compared in 31 countries 1995-2019 and 35 countries 1972-2019, with four country groups in each of the datasets analyzed further. Connections between centralization and changes in debt levels are found to be mostly insignificant and results unstable to the inclusion of lagged changes in de

Ett steg närmare AI-segmentering av MR-bilder Artificiell intelligens (AI) har på kort tid möjliggjort omfattande automatisering av många områden inom medicinsk teknik. En förutsättning för de framsteg som gjorts är dock tillgång till stora mängder data, vilket försvårar utvecklingen av nya lösningar inom bland annat bildanalys. Bristen på data har lett till att alternativa tillvägagångssätt har Semantic segmentation of medical images is an important task with many applications. However, manually delineating 3D images is time-consuming and the demand for automation is high. For many image segmentation tasks, deep learning has provided state-of-the-art results. However, the varying nature of magnetic resonance (MR) images due to factors such as different machine vendors and clinical protoc

Thesis Purpose: The purpose of this study is to explore if virtual influencers can be viewed as capable of developing parasocial relationships and opinion leadership. This will be researched through the virtual influencers source credibility, perceived by the Swedish audience of Instagram. This is based on previous research that has shown that the two concepts of parasocial relationships and opin

Digital technologies have brought new challenges to society, such as data privacy abuses, attacks on democracy, and even military-grade technologies being accessed by civilians. Europe has taken the leadership by regulating different aspects of the digital economy; however, these regulations may create distortions that will harm European businesses. This study tries to draw a picture of the differ

Gröna och förnybara energikällor har under åren sett ökad uppmärksamhet inom forskning och utveckling, där solceller har fått särskild uppmärksamhet. Solceller består av flera lager, eller komponenter, med olika funktioner och den här tesen fokuserar på material som bygger upp det aktiva lagret. Det aktiva lagret är det som absorberar solljus vilket exciterar elektroner till att bilda en elektriskThe interest in energy sources has shifted over the years toward sustainable energy, which has popularized the research in solar cells (among other energy sources). One of the key topics in solar cell research is the power conversion efficiency, and to understand how this can be improved one must understand the photo-induced dynamics of the solar cell material. In this thesis, we modeled the condu

The next industrial revolution has been denoted by Industry 4.0 and is the continuation of the process of knowledge acquisition and further control over the entire production process which has been evolving since the beginning of the industrialization. A paramount driver of Industry 4.0 is the smart sensor. In this master’s thesis, the first stage of a complete smart sensor will be conceptualized

Det här examensarbetet utvecklar ett koncept för infästning av fenor på jetboards som inte intränger på befintliga patent. Det resulterande konceptet medför handlingsfrihet (FTO) och följaktligen tillåter produktion av fenor med originell design. FTO innebär möjligheten till att producera och sälja en produkt utan rättsligt ansvar gentemot ägare av patent. Examensarbetet presenterar och diskuterarThis master thesis generates a concept for the means of attaching fins onto jetboards without infringing on existing patents. The resulting concept establishes freedom to operate (FTO) and enables production of fins with original designs. FTO meaning the possibility of producing and selling a product without legal liability to any patent holders. The thesis further presents and discusses user need

This study evaluated the pilot-scale rapid-prototyping development of liquid plant-based young child formulae, by exploring different sources of proteins, carbohydrates, lipids, and flavours. The study was undertaken in collaboration with an industrial partner thus confidential information was blinded. The raw materials examined consisted of protein blends; Legume 1, Cereal 1, and Cereal 2; Legum

Denna uppsats består utav en empirisk undersökning som syftar till att ta reda på vilka makroekonomiska faktorer som påverkar efterfrågan och därmed även prisnivån på bostäder. Det kommer även framställas en prognos för framtida prisnivåer på bostäder kan utföras med hjälp av kunskapen om hur dessa faktorer påverkar bostadspriser. För att uppnå syftet med uppsatsen har data för olika makroekonomis

Syftet med studien var att explorativt undersöka sambandet mellan social identitet och egen attityd till klimatvänligt beteende och klimatfrågan. Mer specifikt ämnade studien att undersöka huruvida stark identifikation med sju olika sociala identiteter och tillskriven gruppattityd korrelerar med egen attityd. Tvåhundrasextiofyra personer (N=264) deltog i studien genom en digital enkät. Den statistThe aim of the present study was to explore the relationship between social identity and personal attitude towards climate-friendly behaviour and the climate crisis. More specifically, the aim was to investigate whether strong identification with seven different social identities and ascribed group attitude correlates with personal attitude. Two-hundred and sixty-four persons (N=264) participated

Ungdomar har varit föremål för straffrättslig särbehandling i flera sekel. Den nuvarande särbehandlingen föreskrivs i 29 kap. 7 § BrB och medför att om någon begår brott innan hen fyllt 21 år så ska dennes ungdom särskilt beaktas vid straffmätningen. Detta resulterar i en straffnedsättning, s.k. straffrabatt som minskar i förhållande till ökad ålder. Straffrabatten motiveras utifrån ungdomars brisYoung offenders have been specially treated in Swedish criminal law for centuries. Regulations of today are to be found in 29 kap. 7 § BrB and prescribes that anyone who commits a crime before the age of 21 should receive a reduction of their penalty because of their youth. This results in a so-called “penalty discount” that reduces as the age increase. The reasons for the existence of the penalty

How does democracy affect income inequality? Most would expect democracy to reduce income inequality. There is a general consensus that indeed democratizations in Europe during the nineteenth and early twentieth century did decrease income inequality. More recent democratizations, those countries that democratized during the 1970s-1990s, however, do not seem to have had the same effect. The body o

Det var faktiskt för ungefär 80 år sedan, när matematiker som jobbade med att utveckla kärnvapen myntade begreppet för först gången. I grund och botten, använder Monte Carlo metoder slumpmässiga värden för att lösa problem. I det här projektet är det specifikt integrationsproblem. Under ens matematikstudier, kommer vem som helst med ett litet intresse för matematik att stöta på integraler redan iIntegrals are present everywhere in science, and their computation an emphasis in education. When methods of exact computation fail, a great variety of methods of approximation can step in. This project is interested in the Monte Carlo integration methods, an approach, where the integral is approximated based on the Law of Large Numbers. These methods are compared to the methods of numerical quadr

In the last decades Peru experienced an unprecedented reduction in poverty amid a strong and sustainable economic rebound following structural reforms introduced in the 1990s which paralleled a downtrend in income inequality. Using microdata from the National Survey of Households (ENAHO) this study formally tests the simultaneous role of growth and inequality on poverty outcomes from 2007 to 2019.