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Interest in using T1 as a potential MRI biomarker of chronic obstructive pulmonary disease (COPD) has recently increased. Since tobacco smoking is the major risk factor for development of COPD, the aim for this study was to examine whether tobacco smoking, pack-years (PY), influenced T1 of the lung parenchyma in asymptomatic current smokers.

In this paper, we consider both algebraic crossed products of commutative complex algebras A with the integers under an automorphism of A, and Banach algebra crossed products of commutative C*-algebras A with the integers under an automorphism of A. We investigate, in particular, connections between algebraic properties of these crossed products and topological properties of naturally associated d

Gene and protein expression is controlled so that cells can react to changing intra- and extracellular signals by modulating biochemical networks and pathways. We have previously shown that gene expression and the properties of expressed proteins are dynamically correlated. Here we investigated correlations between gene related parameters and gene expression patterns, and found statistically signi

Chronic pancreatitis is a relatively frequent condition usually caused by alcoholic abuse but also due to recurrent gallstone disease, metabolic endocrine disorders and haemochromatosis, among others. Specific types such as hereditary and autoimmune pancreatitis should be particularly kept in mind and emphasized, as they require specific treatment and attention. The possibility to identify gene mu

This study is part of an interactive improvement intervention aimed to facilitate empowerment-based chronic kidney care using data from persons with CKD and their family members. There are many challenges to implementing empowerment-based care, and it is therefore necessary to study the implementation process. The aim of this study was to generate knowledge regarding the implementation process of

The immune system, which is a complex machinery, is based on the highly coordinated expression of a wide array of genes and proteins. The evolutionary history of the human immune system is not well characterised. Although several studies related to the development and evolution of immunological processes have been published, a full-scale genome-based analysis is still missing. A database focused o

Anmälningar av nyutkomna böcker i nordiska språk och äldre nordisk litteratur

Popular Abstract in Swedish Cancer är en av de vanligaste dödsorsakerna i Sverige idag och att kunna ge cancerpatienter en bättre behandling är därför av stort intresse. En del av detta arbete består av att förbättra förståelsen för hur en cellpopulation, eller då speciellt en cancertumör, växer. Ett medel för att öka kunskapen på området är att använda matematiska modeller. Förmågan att kunna föIt it of great importance to increase the knowledge of various cell cycle kinetic parameters and the objective of this thesis is to use stochastic models to interpret Bromodeoxyuridine (BrdUrd) DNA Flow Cytometry (FCM) derived data in order to estimate such parameters. The cell cycle is the process of growth and division that is essential for an organism to increase in size. The cell cycle consist

OBJECTIVE: To develop a psychometrically appropriate brief symptoms measure of carpal tunnel syndrome (CTS). METHODS: Preoperative CTS 11-item symptom severity and 8-item functional status scales from 693 patients (71% women) with CTS were subjected to exploratory factor analysis and item response theory (IRT) analysis yielding a revised CTS symptoms scale. A validation sample of 213 patients (68%

BACKGROUND AND PURPOSE: Clinicians need valid and easily applicable predictors of outcome in patients with hip fracture. Adjusting for previously established predictors, we determined the predictive value of the New Mobility score (NMS) for in-hospital outcome in patients with hip fracture. PATIENTS AND METHODS: We studied 280 patients with a median age of 81 (interquartile range 72-86) years who