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We present a method that combines structure determination using extended x-ray absorption fine structure (EXAFS) measurements and computational chemistry (CC) calculations, EXAFS/CC. Using such an approach, it is possible to obtain a full structure of model complexes or protein metal active sites, although the EXAFS data primarily give radial distance information about the metal ion's nearest neig
Triglycerides and phospholipids in human liver material obtained by fine-needle aspiration biopsy have been determined according to an improved version of a previously developed method. The molar ratios of these lipids have been compared with the same ratios determined on material representing whole liver. The average value of the ratios in the fine-needle specimens was 101% (83-113%) of the corre
The effects of cystatin C and other cysteine proteinase inhibitors on osteoclast formation and differentiation have been investigated. Cystatin C decreased osteoclast formation stimulated by parathyroid hormone (PTH), 1,25(OH)(2)-vitamin D3 or interleukin-6 (IL-6) (in the presence of its soluble receptor) as assessed by the number of tartrate-resistant acid phosphatase (TRAP(+)) multinucleated cel
Qusta ibn Luqa (fl. 860) was a prominent figure in the Graeco-Arabic translation movement that reached its peak in the 9th century. At the request of wealthy and influential commissioners, Qusta translated Greek works on astronomy, mathematics, mechanics and natural science into Arabic. He also produced works of his own: more than sixty treatises are attributed to him. He wrote mainly on medical s
Let C be a simple(1) polygonal chain of n edges in the plane, and let p and q be two arbitrary points on C. The detour of C on (p, q) is defined to be the length of the subchain of C that connects p with q, divided by the Euclidean distance between p and q. Given an epsilon >0, we compute in time O((1)/(epsilon) n log n) a pair of points on which the chain makes a detour at least 1/(1 + epsilon) t
OBJECTIVE: To determine what constitutes normal cervical changes during the second half of pregnancy in parous women delivering at term. DESIGN: The study comprises 21 healthy, pregnant parous women who all gave birth at term. They were examined with transvaginal ultrasound every two weeks from 24 gestational weeks until delivery. Cervical length and width were measured. The inner cervical os was
PURPOSE: To compare conventional MR imaging, echo-planar diffusion-weighted imaging (EP-DWI) and spin-echo diffusion-weighted imaging (SE)-DWI at radiological diagnosis of acute stroke. MATERIAL AND METHODS: Twenty-seven patients (30-85 years old) were examined. Clinical examination was performed before MR imaging. All MR examinations were assessed by an experienced neuroradiologist blinded to cli
Essential oils are volatile and can have good antimicrobial activity. We compared the effects of oil of basil ( Ocimum basilicum) and essential oil components ( thymol, carvacrol, and salicylaldehyde) to those of a placebo when placed in the ear canal of rats with experimental acute otitis media caused by pneumococci or Haemophilus influenzae. Progress was monitored by otomicroscopic examination a
Dose calculations for treatment planning of photon beam radiotherapy require a model of the beam to drive the dose calculation models. The beam shaping process involves scattering and filtering that yield radiation components which vary with collimator settings. The necessity to model these components has motivated the development of multisource beam models. We describe and evaluate clinical photo
Föreliggande delrapport avser inledande studier av putsens fuktberoende rörelser, både initialkrympning vid den första uttorkningen och rörelser vid upprepad uppfuktning och uttorkning.
The product-service system (PSS) concept has been proposed as a way of dealing with unsustainable patterns of consumption in the business-to-consumer (B2C) domain. Existing alternatives to traditional consumption based on ownership, such as car sharing, communal washing centres and tool sharing schemes, indicate that more sustainable patterns of consumption may be found for other household functio
OBJECTIVE - Consumption of a meal high in resistant starch or soluble fiber (P-glucan) decreases peak insulin and glucose concentrations and areas under the curve (AUCs). The objective was to determine whether the effects of soluble fiber and resistant starch on glycemic variables are additive. RESEARCH DESIGN AND METHODS - Ten normal-weight (43.5 years of age, BMI 22.0 kg/m(2)) and 10 overweight
Lipids may serve as coupling factors in KATP-independent glucose sensing in β-cells. We have previously demonstrated that β-cells harbor lipase activities, one of which is the hormone-sensitive lipase. Whether β-cell lipases are critical for glucose-stimulated insulin secretion (GSIS) by providing lipid-derived signals from endogenous lipids is unknown. Therefore, using a lipase inhibitor (orlista
A comparison is made between the development trends experience over the last decades by the steel and papermaking industries, respectively. These two industrial branches, although totally different in their technical nature, are subject to similar pressures from their external environment, notably increasing requirements for environmental protection and more efficient raw material management. Such
The potential modes of transmission for hepatitis C virus (HCV) infections were studied using a multivariate analysis of risk factor exposure among 51 2nd generation anti-HCV and HCV-RNA positive and matched anti-HCV negative blood donors. The following variables were found to be independently associated with anti-HCV and HCV-RNA positivity: intravenous drug use (IVDU) (p < 0.001), blood transfusi
Proteins interacting with the human PDGF (platelet-derived growth factor) b-receptor were isolated using immobilized peptides derived from the receptor C-terminus as a bait. We identified two PDZ domain proteins, namely NHERF (Na+/H+ exchanger regulatory factor, also called EBP50) and NHERF2 (E3KARP, SIP-1, TKA-1), which have been shown previously to associate with the murine PDGF receptor [Maudsl
