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Personality-dependent inter- and intraspecific foraging competition in the invasive round goby, Neogobius melanostomus

This study examines the impact of boldness on foraging competition of the highly invasive round goby Neogobius melanostomus Pallas 1815. Individual risk tolerance, or boldness, was measured as the time to resume movement after a simulated predation strike. Fish that resumed movement faster were categorized as “bold,” fish that took more time to resume movement were categorized as “shy” and those t

Accurate Indoor Positioning Based on Learned Absolute and Relative Models

To improve the accuracy of indoor positioning systems it can be useful to combine different types of sensor data. This paper describes deep learning methods both for estimating absolute positions and for performing pedestrian dead reckoning, and then how to combine the resulting estimates using weighted least squares optimization. The positioning model is based on a custom neural network which use

Atrial Fibrillation Episode Patterns and Their Influence on Detection Performance

Existing studies offer little insight on how atrial fibrillation (AF) detection performance is influenced by the properties of AF episode patterns. The aim of this study is to investigate the influence of AF burden and median AF episode length on detection performance. For this purpose, three types of AF detectors, using either information on rhythm, rhythm and morphology, or ECG segments, were in

Natural history study of factor IX deficiency with focus on treatment and complications (B-Natural)

Introduction: Haemophilia B (HB) is less well studied than haemophilia A (HA); despite similarities between the two inherited bleeding disorders, important differences remain that require further research. Aim: B-Natural is a multi-centre, prospective, observational study of HB, designed to increase understanding of clinical manifestations, treatment, quality-of-life (QoL), inhibitor development,

Peritoneal carcinomatosis : cytoreductive surgery and HIPEC--overview and basics

Tumor involvement of the peritoneum-peritoneal carcinomatosis-is a heterogeneous form of cancer that had been generally regarded as a sign of systemic tumor disease and as a terminal condition. The multimodal treatment approach for patients with peritoneal carcinomatosis, which had been conceived and developed, consists of what is known as cytoreductive surgery, followed by hyperthermic intraperit

Long-term results of cytoreduction and HIPEC followed by systemic chemotherapy

Cytoreduction followed by hyperthermic intraperitoneal chemotherapy is a treatment option for peritoneal surface malignancies in The Netherlands. This treatment has been available for more than 10 years. Therefore, long-term results on survival and quality of life can now be studied. With these results, the true long-term benefits of this new management strategy can be determined.

A Micro-Level Simulation Model for Analyzing the Use of MSUs in Southern Sweden

A mobile stroke unit (MSU) is a special type of ambulance, where stroke patients can be diagnosed and provided intravenous treatment, hence allowing to cut down the time to treatment for stroke patients. We present a discrete event simulation (DES) model to study the potential benefits of using MSUs in the southern health care region of Sweden (SHR). We included the activities and actions used in

Quantitative intra-operative assessment of peritoneal carcinomatosis - a comparison of three prognostic tools

AIMS: Selecting patients for cytoreductive surgery and hyperthermic intra-peritoneal chemotherapy (HIPEC) remains challenging. We compared the predictive power of three intra-operative assessment tools of peritoneal involvement of colorectal cancer.METHODS: Ninety-two procedures (1999-2005) were prospectively scored using the Simplified Peritoneal Cancer Index (SPCI) and 7 Region Count. The Perito

The eligibility for local-regional treatment of peritoneal surface malignancy

At the Fifth International Workshop on Peritoneal Surface Malignancy, held in Milan, the consensus on technical aspects of cytoreductive surgery (CRS) for peritoneal surface malignancy was obtained through the Delphi process. General conflicting points concerning the eligibility to the local-regional therapy were discussed and voted.

Learning curve of combined modality treatment in peritoneal surface disease

BACKGROUND: Cytoreductive surgery with intraperitoneal chemotherapy has emerged as a new standard approach for peritoneal surface disease. This study investigated the learning curve of this combined modality treatment at a single institute.METHODS: Variables analysed over three consecutive treatment periods (1996-1998, 1999-2002 and 2003-2006) included number of abdominal regions affected, Simplif

Appendiceal neoplasms and pseudomyxoma peritonei : a population based study

BACKGROUND: Pseudomyxoma peritonei (PMP) is a rare disease with an estimated incidence of 1 per million per year, and is thought to originate usually from an appendiceal mucinous epithelial neoplasm. However it is not known exactly how often these neoplasms lead to PMP. The aim of this study is to investigate the incidence of both lesions and their relation.METHODS: The nationwide pathology databa

Measuring electric properties of a conductive electric road

Electric Road Systems (ERS) is an emerging new technology that aim to electrify land transport by supplying electric vehicles (EV) with power. By providing EV's the possibility to charge while driving i.e. dynamic charging the battery size can be greatly decreased compared to a solution with nighttime and fast charging. The evaluation of the potential of ERS has already been published in a number

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Three patients, men aged 47 and 30 and a woman aged 48 years, presented with appendicitis-like symptoms, progressive abdominal distension, and an ovarian pelvic mass, respectively. All three were diagnosed with pseudomyxoma peritonei. Treatment consisted of cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy (HIPEC). After a mean follow-up of 64 months (range: 19-89) after

Survival analysis of pseudomyxoma peritonei patients treated by cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

OBJECTIVE: To evaluate the survival of patients with pseudomyxoma peritonei (PMP) treated by cytoreductive surgery and intraoperative hyperthermic intraperitoneal chemotherapy (HIPEC), and to identify factors with prognostic value.SUMMARY BACKGROUND DATA: PMP is a clinical syndrome characterized by progressive intraperitoneal accumulation of mucous and mucinous implants, usually derived from a rup

Progression of pseudomyxoma peritonei after combined modality treatment : management and outcome

BACKGROUND: Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is a treatment strategy for pseudomyxoma peritonei (PMP) with curative intent. The aim of this study was to determine the patterns of failure in patients who underwent such a procedure and to evaluate management and outcome of progressive disease.METHODS: After exclusion of patients with overt malignancy