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Role of proneurotensin as marker of paediatric coeliac disease

Neurotensin (NT) is a gut hormone functioning proinflammatory through nuclear factor kappa B (NF-κB) and interleukin (IL)−8 secretion or anti-inflammatory through epidermal growth factor receptors. NT mRNA is down-regulated in duodenal biopsies of children with untreated coeliac disease. The aim of this study was to investigate if plasma pro-NT levels correlated with the degree of intestinal mucos

Young, Small, and Imprintable : Assessing Progress and Exploring Future Directions in New Venture and Small Business Research

Liabilities of newness and smallness as well as other issues (e.g., “imprinting”) that affect nascent firms represent foundational entrepreneurship issues. The articles in this Special Issue examine if and how these critical issues have changed over time, especially given recent innovations (e.g., crowdfunding) and other trends in society. We believe that a special issue devoted to these topics is

An age structured cell cycle model with crowding

We study a two compartment, nonlinear, age structured model for the cell cycle. The phases of the cell cycle G1, S, G2 and M are grouped into two phases, which we call Phase 1 and Phase 2, where Phase 1 consists of the phase G1 and Phase 2 consists of the phases S, G2 and M. It is assumed that Phase 1 has a variable duration while the duration of Phase 2 is fixed. The model consists of a system of

Interactive roles of the cerebellum and striatum in sub-second and supra-second timing : Support for an initiation, continuation, adjustment, and termination (ICAT) model of temporal processing

The contributions of cortico-cerebellar and cortico-striatal circuits to timing and time perception have often been a point of contention. In this review we propose that the cerebellum principally functions to reduce variability, through the detection of stimulus onsets and the sub-division of longer durations, thus contributing to both sub-second and supra-second timing. This sensitivity of the c

Climate regulation, energy provisioning and water purification : Quantifying ecosystem service delivery of bioenergy willow grown on riparian buffer zones using life cycle assessment

Whilst life cycle assessment (LCA) boundaries are expanded to account for negative indirect consequences of bioenergy such as indirect land use change (ILUC), ecosystem services such as water purification sometimes delivered by perennial bioenergy crops are typically neglected in LCA studies. Consequential LCA was applied to evaluate the significance of nutrient interception and retention on the e

A New Method for Endoscopic Sampling of Submucosal Tissue in the Gastrointestinal Tract : A Comparison of the Biopsy Forceps and a New Drill Instrument

Background. Sampling of submucosal lesions in the gastrointestinal tract through a flexible endoscope is a well-recognized clinical problem. One technique often used is endoscopic ultrasound-guided fine-needle aspiration, but it does not provide solid tissue biopsies with preserved architecture for histopathological evaluation. To obtain solid tissue biopsies from submucosal lesions, we have const

Fear : Introduction to Special Issue

Fear needs dealing with. Fear demands to be abated, countered or turned into something else, contributing and curtailing how we ‘do’ being human beings. This special issue of the European Journal of Cultural Studies addresses fear within media and popular culture, adopting a cultural studies approach to fear in a variety of socio-cultural and political contexts. A cultural studies approach allows

Documentary Imaginary : Production and audience research of The Act of Killing and The Look of Silence

Oppenheimer describes The Act of Killing as a ‘documentary about the imagination. We are documenting the ways we imagine ourselves, the ways we know ourselves’. This research analyses the documentary films The Act of Killing (Director Oppenheimer, co-directors Christine Cynn and anonymous 2012) and The Look of Silence (director Oppenheimer 2014), and the documentary imaginary. The research combine

Agricultural breadbaskets shift poleward given adaptive farmer behavior under climate change

Modern food production is spatially concentrated in global "breadbaskets". A major unresolved question is whether these peak production regions will shift poleward as the climate warms, allowing some recovery of potential climaterelated losses. While agricultural impacts studies to date have focused on currently cultivated land, the Global Gridded Crop Model Intercomparison Project (GGCMI) Phase 2

Iscensatt inkludering. : Gemenskap som mål och utmaning på socionomutbildningen

Konflikter mellan olika samhällsgrupper och människors fördomar har länge intresserat samhällsvetenskapliga forskare. Många har också sökt svar på frågan om vad som kan göras för att överbrygga och minska dessa klyftor, splittringar och fördomar. Denna avhandling relaterar till denna diskussion och forskningsprocessen har ägt rum i flera steg. Först har en experimentell praxis utvecklats för att mConflicts between different social groups and people's prejudices have interested social science researchers for a long time. Many have also sought answers to the question of what can be done to bridge and reduce these gaps, divisions and prejudices. This dissertation relates to these discussions and the research process has taken place in several stages. First, an experimental practice has been d

Framtidsdialoger : en metodbok

Framtidsdialoger är en ny metod som bidrar till att utveckla biblioteksverksamheten i en kommun utifrån lokala förutsättningar med biblioteksplanen som nod. Denna metodbok har två delar: en handbok med konkreta instruktioner till dem som vill bli Framtidslotsar och genomföra Framtidsdialoger och en del med reflektioner kring den regionala biblioteks utvecklarrollen och processen med att utveckla e

Language and Its Limits : Meaning, Reference and the Ineffable in Buddhist Philosophy

Buddhist schools of thought share two fundamental assumptions about language. On the one hand, language (śabda) is identified with conceptual thinking (kalpanā), which according to the Buddhist doctrine (dharma) separates us from the momentary and fleeting nature of reality (satya, “truth”). Language is comprised of generally applicable forms, which fuel the reificatory proclivity for clinging to

Parents experience a sense of guilt when their newborn is diagnosed small for gestational age, SGA. A grounded theory study in Sweden

Background: To become a parent of a child who is born small for gestational age can lead to challenges in addition to the newly acquired parenting role. There is currently a lack of knowledge regarding parents' experiences of having a child born small for gestational age. Purpose: The purpose of this study was to describe the experience of becoming a parent of a child small for gestational age Des

Validity and reliability of the Swedish version of the Self-Efficacy for Managing Chronic Disease scale for individuals with systemic sclerosis

ObjectiveTo investigate aspects of validity and reliability of the Swedish version of the Self-Efficacy for Managing Chronic Disease (SEMCD-Swe) scale in systemic sclerosis (SSc).Method: A forward–backward translation procedure was used. Content validity was assessed through interviews with 11 people with SSc and 10 healthcare professionals. Construct validity, internal consistency, test–retest re

Development of alginate and gelatin-based pleural and tracheal sealants

Pleural and tracheal injuries remain significant problems, and an easy to use, effective pleural or tracheal sealant would be a significant advance. The major challenges are requirements for adherence, high strength and elasticity, dynamic durability, appropriate biodegradability, and lack of cell or systemic toxicity. We designed and evaluated two sealant materials comprised respectively of algin

Extracellular fluid, cerebrospinal fluid and plasma biomarkers of axonal and neuronal injury following intracerebral hemorrhage

Spontaneous intracerebral hemorrhage (ICH) is the most devastating form of stroke. To refine treatments, improved understanding of the secondary injury processes is needed. We compared energy metabolic, amyloid and neuroaxonal injury biomarkers in extracellular fluid (ECF) from the perihemorrhagic zone (PHZ) and non-injured (NCX) brain tissue, cerebrospinal fluid (CSF) and plasma. Patients (n = 11