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The endangered São Tomé Grosbeak Neospiza concolor is the world's largest canary

The São Tomé Grosbeak Neospiza concolor, endemic to the island of São Tomé (Gulf of Guinea), is one of the least known birds in the world. Formerly considered to be an aberrant weaver (Ploceidae), it is currently placed in a monotypic genus within the true finches (Fringillidae). Phylogenetic inference based on mitochondrial and nuclear sequences confidently identifies N. concolor as an Old World

The importance of benthic-pelagic coupling for marine ecosystem functioning in a changing world

Benthic-pelagic coupling is manifested as the exchange of energy, mass, or nutrients between benthic and pelagic habitats. It plays a prominent role in aquatic ecosystems, and it is crucial to functions from nutrient cycling to energy transfer in food webs. Coastal and estuarine ecosystem structure and function are strongly affected by anthropogenic pressures; however, there are large gaps in our

The association between health utility and joint status among people with severe haemophilia A : findings from the KAPPA register

INTRODUCTION: People with severe haemophilia A have reportedly impaired health related quality of life (utility) mainly due to recurrent bleeding, arthropathy and treatment burden.AIM: To estimate utilities and evaluate their potential correlates - most importantly the joint status - among people with severe haemophilia A.METHODS: In this cross-sectional study, eligible participants had severe hae

Don't forget to look down - collaborative approaches to predator conservation

ABSTRACT: Finding effective ways of conserving large carnivores is widely recognised as a priority in conservation. However, there is disagreement about the most effective way to do this, with some favouring top-down 'command and control' approaches and others favouring collaboration. Arguments for coercive top-down approaches have been presented elsewhere; here we present arguments for collaborat

Comparative burden of arthropathy in mild haemophilia : a register-based study in Sweden

INTRODUCTION: Mild haemophilia is a congenital bleeding disorder affecting males. The burden of arthropathy in mild haemophilia has not been comprehensively described.AIM: The aim of this study was to compare the incidence, age at diagnosis and surgery for arthropathy and related hospitalizations between people with mild haemophilia and the general population in Sweden.METHODS: This was a register

Psychometric properties of the Swedish version of the Functional Disability Inventory

Chronic or recurrent pain is a common experience in children and adolescents. One questionnaire that is frequently used to assess pain-related disability is the Functional Disability Inventory (FDI). The aim of this study was to evaluate the psychometric properties of the Swedish version of the FDI. The patient group consisted of 30 patients, 8-17 years old. The comparison group consisted of 78 pu

Radially resolved simulations of collapsing pebble clouds in protoplanetary discs

In the Solar System, asteroids and Kuiper belt objects as well as comets are remnant planetesimals from the time of planet formation. Interactions between solids and gas inside a protoplanetary disc can, e.g. through the streaming instability, form gravitationally bound planetesimal-mass clouds of pebbles. Such clouds will inevitably have inelastic collisions between pebbles, lose energy and exper

Formation of Pebble-Pile Planetesimals and the Interior Structure of Comets

Bildandet av planeter äger rum i skivor av gas, stoft och is runt nybildade stjärnor. Den här processen är inte helt förstådd men det första steget tros vara växten från mikrometer-stora stoftkorn till mm-cm-stora småstenar genom sammanväxande kollisioner. Vid de här storlekarna studsar stenarna eller går sönder snarare än fastnar i varandra när de kolliderar så tillväxten avstannar. Dessutom kännPlanets form in protoplanetary discs of gas, dust and ice around newborn stars. In the Solar System, not only planets are found as a result from the time of planet formation, but also remnant planetesimals in the form of asteroids, Kuiper belt objects and comets. Recent observations, e.g. by the space mission Rosetta, have found that comets are porous objects barely able to hold themselves togethe

Distributed Approach to the Holistic Resource Management of a Mobile Cloud Network

The Mobile Cloud Network is an emerging cost and capacity heterogeneous distributed cloud topological paradigm that aims to remedy the application performance constraints imposed by centralised cloud infrastructures. A centralised cloud infrastructure and the adjoining Telecom network will struggle to accommodate the exploding amount of traffic generated by forthcoming highly interactive applicati

Fundamental bounds on MIMO antennas

Antenna current optimization is often used to analyze the optimal perfor-mance of antennas. Antenna performance can be quantied in e.g., minimumQ-factor and maximal gain over Q-factor ratio. The performance of MIMOantennas is more involved and a single parameter is, in general, not sucientto quantify it. Here, the capacity of an idealized channel is used as the mainperformance quantity. An optimiz

A note on EFSA’s ongoing efforts to increase transparency of uncertainty in scientific opinions

This is a comment on Lofstedt and Bouder?s paper, which explores the prospects of evidence based uncertainty analysis in Europe, focusing on the ongoing development on uncertainty analysis at the European Food Safety Authority (EFSA). We very much welcome a discussion on the need to develop better treatment and communication of uncertainty in risk analysis, as we believe that such discussion is loThis is a comment on Lofstedt and Bouder’s paper, which explores the prospects of evidence based uncertainty analysis in Europe, focusing on the ongoing development on uncertainty analysis at the European Food Safety Authority (EFSA). We very much welcome a discussion on the need to develop better treatment and communication of uncertainty in risk analysis, as we believe that such discussion is lo

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In the normal case, a reflexive pronoun is bound within its containing clause. More exceptionally, a reflexive is instead related to a binder in a higher clause – a phenomenon known as long distance binding. Long distance binding can be found in Norwegian, but as I will show here, with considerable variation between speakers. Quite a few speakers accept long distance binding only across indefinite

Effect of mergers and acquisitions on drug discovery : perspective from a case study of a Japanese pharmaceutical company

The pharmaceutical industry has experienced intermittent waves of mergers and acquisitions (M&As) since the 1980s and recently appeared to be in yet another wave. Previous studies indicated rather negative impacts of consolidation on research and development, suggesting that they do not necessarily lead to long-term reinforcement of research capabilities, although they may enrich the drug pipe

Contribution of structural biology to clinically validated target proteins

We identified six groups of diseases expected to cause serious future health issues on the basis of a WHO report. Approved drugs for these diseases were associated with 409 target proteins; however, the percentage of selected proteins with full-length structural information deposited in the Protein Data Bank (PDB) was only 9.8%. The reason for the low percentage may be as a result of a disproporti