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Correlating two methods of quantifying fungal activity: Heat production by isothermal calorimetry and ergosterol amount by gas chromatography-tandem mass spectrometry

Two methods of quantifying fungal activity have been compared and correlated: isothermal calorimetry for measuring heat production and gas chromatography-tandem mass spectrometry (GC-MS/MS) for measuring ergosterol, a proxy for biomass. The measurements were made on four different fungi: Penicillium roqueforti, Cladosporiurn cladosporioides, Neopetromyces muricatus and the dry rot fungus Serpula l

Loss of Wnt-5a protein is associated with early relapse in invasive ductal breast carcinomas.

Previous in vitro studies have implied that the Wnt-5a gene plays a role as a tumor suppressor. To explore the clinical relevance of this concept, 96 primary invasive breast carcinomas were stained with a novel anti-Wnt-5a antibody. Loss of Wnt-5a protein expression, evident in 44% of the invasive ductal carcinomas (n = 59), was significantly associated with higher histological grade (P = 0.01) an

Staples, Institutions and Growth. Competitiveness of Guatemalan Exports 1524-1945

Popular Abstract in Swedish Avhandlingen analyserar Guatemalas råvaruexport under perioden 1524-1945.In the integrated institutional-staples-‘vent for surplus’ approach, the opening of trade occurs because of initial demand. Once demand is determined, competitiveness is a function of transportation costs, entrepreneurship, capital, land and labour costs, as well as the role played by the State. When all these factors promote competitiveness within an institutional framework that decreased transac

Change in knee kinematics during gait after eccentric isokinetic training for quadriceps in subjects submitted to anterior cruciate ligament reconstruction

Knee kinematics after anterior cruciate ligament (ACL) reconstruction is of interest in studies evaluating the effect of training programs. Many studies have addressed knee flexion/extension but not valgus/varus movements. Considering that joint stability is a major concern in ACL reconstruction surgery, movements occurring in the frontal plane of the knee also deserve attention. Knee extensor tor

Renal arteries covered by aortic stents: clinical experience from endovascular grafting of aortic aneurysms

OBJECTIVES: During the endovascular repair of abdominal aortic aneurysms (AAAs), effective anchoring of the stent-graft is difficult in the presence of a short infrarenal aneurysm neck. The aim of this study was to investigate renal artery patency and renal function after deployment of graft anchoring stents across the renal arteries. DESIGN: Retrospective open study. PATIENTS: Twenty-five renal a

Nocturia: morbidity and management in adults

Nocturia is an increasingly prevalent and bothersome urinary symptom associated with considerable impact and morbidity in later life. Nocturnal frequency is associate with a number of underlying pathologies, both related and unrelated to the lower urinary tract. Following careful assessment, diagnosis and management, the condition is amenable to amelioration, if not complete cure in the majority o

A 6 hour working day - effects on health and well-being

The effect of the total amount of work hours and the benefits of a shortening is frequently debated, but very little data is available. The present study compared a group (N = 41) that obtained a 9 h reduction of the working week (to a 6 h day) with a comparison group (N = 22) that retained normal work hours. Both groups were constituted of mainly female health care and day care nursery personnel.

Ionic binding of C3 to the human pathogen Moraxella catarrhalis is a unique mechanism for combating innate immunity

Moraxella catarrhalis ubiquitous surface proteins A1 and A2 (UspA1/A2) interfere with the classical pathway of the complement system by binding C4b-binding protein. In this study we demonstrate that M. catarrhalis UspA1 and A2 noncovalently and in a dose-dependent manner bind both the third component of complement (C3) from EDTA-treated serum and methylamine-treated C3. In contrast, related Moraxe

Changes in incidence and prevalence of vertebral fractures during 30 years

The age and sex-specific incidence and prevalence of vertebral compression fractures were compared between the 1950s and 1980s in an urban population. In women over 80 years of age the incidence of symptomatic vertebral fractures has increased approximately four times; in elderly men even more. Mainly, low-energy trauma has caused these fractures. Thus, one clinical manifestation of osteoporosis--

'EUROPART'. Airborne particles in the indoor environment. A European interdisciplinary review of scientific evidence on associations between exposure to particles in buildings and health effects

The relevance of particle mass, surface area or number concentration as risk indicators for health effects in non-industrial buildings has been assessed by a European interdisciplinary group of researchers (called EUROPART) by reviewing papers identified in Medline, Toxline, and OSH. Studies dealing with dermal effects or cancer or specifically addressing environmental tobacco smoke, house dust-mi

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The effect and possible mechanisms of action of aminoguanidine (a preferential iNOS inhibitor) has been studied on cardiovascular damages and overproduction of reactive nitrogen species in streptozotocin-induced diabetic rats. MATERIALS AND METHODS: 40 rats were divided into five groups (control and diabetic, with or without aminoguanidine treatment, diabetic with insulin treatment) and oxidative

Viktigt att upptäcka ärftliga fall av kolorektal- och endometriecancer. Mutationer hos »HNPCC-individer» kan orsaka flera tumörsjukdomar

Hereditary Nonpolyposis Colorectal Cancer (HNPCC) is one of our most common hereditary cancer syndromes and confers an increased risk for several tumor types, with the greatest lifetime risks being for colorectal cancer and endometrial cancer. Hereditary mutations in one of several mismatch-repair (MMR) genes cause the syndrome, and 39 such mutations, involving the genes MLH1, MSH2 and MSH6, have

Unraveling the magnetic carriers of igneous cores from the Atlantic, Pacific, and the southern Indian oceans with rock magnetic characterization

Previous rock magnetic investigations of oceanic basement samples have been mainly restricted by single drill holes of dredge collections. In this study, we present new and published data on the rock magnetic properties of igneous rock samples recovered during seven Ocean Drilling Program (ODP) legs in the Atlantic, Pacific, and the southern Indian oceans. The recovered igneous rocks from these le

Osteoarthritis - an update

Osteoarthritis (sometimes called “arthrosis” or “osteoarthrosis”) often entails a slow and gradual deterioration of the joint that may sometimes lead to its total destruction and the need for an operation to replace it. However, for most patients with osteoarthritis, surgical treatment never becomes necessary, and their symptoms can be dealt with satisfactorily by self management, by non-pharmacol