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Surface Chemistry of Alanine on Ni{111}

The adsorption of l-alanine on Ni{111} has been studied as a model of enantioselective heterogeneous catalysts. Synchrotron-based X-ray photoelectron spectroscopy and near-edge X-ray absorption fine structure (NEXAFS) spectroscopy were used to determine the chemical state, bond coordination, and out-of-plane orientation of the molecule on the surface. Alanine adsorbs in anionic and zwitterionic fo

No specific effect of whole-body vibration training in chronic stroke: a double-blind randomized controlled study.

OBJECTIVE: To evaluate the effects of whole-body vibration (WBV) training in individuals after stroke. DESIGN: A double-blind randomized controlled study with assessments pre- and posttraining. SETTING: A university hospital rehabilitation department. PARTICIPANTS: Participants (N=31; mean age ± SD, 62±7y; 6-101mo poststroke) were randomized to an intervention group or a control group. INTERVE

Thrombin generation in abdominal sepsis is Rho-kinase-dependent.

Sepsis causes severe derangements of the coagulation system. However, the signaling mechanisms regulating sepsis-induced thrombin generation remain elusive. Herein, we hypothesized that Rho-kinase might be an important regulator of thrombin generation in abdominal sepsis. Abdominal sepsis was induced by cecal ligation and puncture (CLP) in C57Bl/6 mice. Thrombin generation, coagulation factors, lu

Accuracy of a Panel of 5 Cerebrospinal Fluid Biomarkers in the Differential Diagnosis of Patients With Dementia and/or Parkinsonian Disorders

Objective: To assess the ability of 5 cerebrospinal fluid (CSF) biomarkers to differentiate between common dementia and parkinsonian disorders. Design: A cross-sectional, clinic-based study. Participants: Cerebrospinal fluid samples (N=453) were obtained from healthy individuals serving as controls and from patients with Parkinson disease (PD), PD with dementia (PDD), dementia with Lewy bodies (DL

Polymer Adsorption from Bulk Solution onto Planar Surfaces: Effect of Polymer Flexibility and Surface Attraction in Good Solvent

Adsorption of uncharged homopolymers of various flexibilities in good solvent onto planar surfaces Lit various polymer-surface interaction strengths have been investigated by employing a coarse-grained bead-spring polymer model using simulation techniques. The polymer flexibility ranged from fully flexible to rod-like polymers, and the adsorption strength varied from weak to strong adsorption. Equ

Long-term Results of Cardiac Resynchronization Therapy; A Comparison Between CRT-Pacemakers Versus Primary Prophylactic CRT-Defibrillators.

Cardiac resynchronization Therapy (CRT) with or without a defibrillator has a positive effect on mortality and morbidity for patients with heart failure. However, comparisons between CRT-Defibrillators (CRT-D) and CRT-Pacemakers (CRT-P) are relatively scarce outside the clinical trial setting. This study aimed to assess baseline characteristics in relation to long-term prognosis in patients treate

Having to focus on doing rather than being-Nurse assistants' experience of palliative care in municipal residential care settings.

BACKGROUND: Palliative care should be provided, irrespective of setting to all patients facing a life-threatening illness and to their families. The situation and needs of older people differ from those of younger people since they often have several co-existing diseases and health complaints. This implies an extensive need for care and for longer periods of palliative care. The main providers of

Soot reference materials for instrument calibration and intercomparisons: a workshop summary with recommendations

Soot, which is produced from biomass burning and the incomplete combustion of fossil and biomass fuels, has been linked to regional and global climate change and to negative health problems. Scientists measure the properties of soot using a variety of methods in order to quantify source emissions and understand its atmospheric chemistry, reactivity under emission conditions, interaction with solar

Distinct structural and optical regimes in natural silk spinning

This study investigates the relationship between birefringence and mechanical properties in the dragline silk of the gold orb weaving spider Nephila edulis. Using a custom birefringence-tensile testing device, we probed the orientation and water-induced swelling of fibers spun at variety of drawing rates ranging from 0.003 to 400 mm s-1. Our results indicate that based upon drawing rate, silk fibe

[F-18]Fluorodeoxyglucose - positron emission tomography/computed tomography improves staging in patients with high-risk muscle-invasive bladder cancer scheduled for radical cystectomy

Objective. The aim of this study was to evaluate the clinical use of [F-18]-fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) in addition to conventional preoperative radiological investigations in a defined group of patients with high-risk muscle-invasive bladder cancer. Materials and methods. In total, 103 patients with high-risk muscle-invasive bladder cancer defi

Determining PPN gamma with Gaia's astrometric core solution

The ESA space astrometry mission Gala, due for launch in early 2012, will in addition to its huge output of fundamental astrometric and astrophysical data also provide stringent tests of general relativity. In this paper we present an updated analysis of Gaia's capacity to measure the PPN parameter gamma as part of its core astrometric solution. The analysis is based on small-scale astrometric sol

Population size of lions in Yankari Game Reserve as revealed by faecal DNA sampling

Studies have shown that lion (Panthera leo) populations in West Africa are small, isolated and fragmented. In Nigeria, lions have disappeared from unprotected areas and are nowadays found only in parks and reserves where these populations may still decline. It is therefore urgent to obtain reliable estimates of population sizes at different localities. Direct observational surveys may either fail

VOF MODELING AND ANALYSIS OF FILMWISE CONDENSATION BETWEEN VERTICAL PARALLEL PLATES

In this study, a computational model has been developed to predict condensation heat transfer between vertical parallel plates. Transient simulations of filmwise condensation in a small two-dimensional parallel plate passage are performed. The Volume of Fluid (VOF) method is used to track the vapor liquid interface. The Geometric Reconstruction Scheme, which is a Piecewise Linear Interface Calcula

Regional differences in levels of chlorinated and brominated pollutants in mother's milk from primiparous women in Sweden

Early life exposure to halogenated persistent organic pollutants, such as polychlorinated biphenyls (PCBs), the DDT metabolite p,p'-dichlorodiphenyldichloroethane (p,p'-DDE), polybrominated diphenylethers (PBDEs), and hexabromocyclododecane (HBCD), may affect human health. We determined if there are regional differences in mother's milk levels of these compounds in Sweden. In year 2000-2004, milk

Reversal of stroke induced lymphocytopenia by levodopa/benserazide treatment.

Evidences exist that dopamine is involved in T-cell homeostasis. Here, we investigated if daily treatment with levodopa (20mg/kg)/benserazide (15mg/kg) regulates the number of T-cells in the blood of Sprague Dawley rats subjected to transient occlusion of the middle cerebral artery (tMCAO). T-cells and associated inflammatory cytokines were analyzed in the blood one week after tMCAO. Treatment wit

Passenger strand loading in overexpression experiments using microRNA mimics.

MicroRNAs (miRNAs) are important regulators of gene function and manipulation of miRNAs is a central component of basic research. Modulation of gene expression by miRNA gain-of-function can be based on different approaches including transfection with miRNA mimics; artificial, chemically modified miRNA-like small RNAs. These molecules are intended to mimic the function of a miRNA guide strand while

Proteomic analysis and discovery using affinity proteomics and mass spectrometry.

Antibody-based microarrays are a rapidly evolving affinity-proteomic methodology that recently has shown great promise in clinical applications. The resolution of these proteomic analyses is, however, directly related to the number of data-points, i.e. antibodies, included on the array. Currently, this is a key bottleneck due to limited availability of numerous highly-characterized antibodies. Her

Low prevalence of irritable bowel syndrome in primary health care in four Swedish counties.

Abstract Objective. Few large-scale studies have examined the prevalence of irritable bowel syndrome (IBS) and the number of visits among IBS patients in a primary health care setting. The aim of this study was to assess the prevalence of IBS in primary health care in four Swedish counties. Another aim was to study the number of visits among the IBS patients. Design. A register-based study. Settin