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Electron bunch compressors formed of achromat arcs have a natural advantage over the more commonly used chicane compressors in that linearization of the longitudinal phase space is of the correct sign to compensate for the curvature imprinted by rf acceleration. Here we extend the utility of arc compressors to enable variation of the longitudinal compaction within a fixed footprint. We also show t
Crystals, nanoparticles, and fibrils catalyze the generation of new aggregates on their surface from the same type of monomeric building blocks as the parent assemblies. This secondary nucleation process can be many orders of magnitude faster than primary nucleation. In the case of amyloid fibrils associated with Alzheimer's disease, this process leads to the multiplication and propagation of aggr
The 2030 Agenda for Sustainable Development and its seventeen Sustainable Development Goals were adopted by the United Nations General Assembly in 2015. It is a bold agenda for global social, environmental and economic development, with human health as a central theme. Even though substantial improvements in health have been achieved during the last decades, every year over 5 million children die,
Context. Several new multi-object spectrographs are currently planned or under construction that are capable of observing thousands of Galactic and extragalactic objects simultaneously. Aims. In this paper we present a probabilistic fibre-to-target assignment algorithm that takes spectrograph targeting constraints into account and is capable of dealing with multiple concurrent surveys. We present
Background: Imbalances in the gut microbial community (dysbiosis) of vertebrates have been associated with several gastrointestinal and autoimmune diseases. However, it is unclear which taxa are associated with gut dysbiosis, and if particular gut regions or specific time periods during ontogeny are more susceptible. We also know very little of this process in non-model organisms, despite an incre
Recent studies have shown that magnetic fields in the solar corona are strong enough to significantly mix the two 3p43d 4D5/2,7/2 levels in Cl-like Fe X. This mixing gives rise to a magnetically induced transition (MIT) component in the bright Fe X 257.3 Å line, commonly observed by current instrumentation, that can be used for coronal magnetic field diagnostics. This line, commonly observed by th
Background: Traumatic brain injury (TBI) is a major cause of disabilities and mortality worldwide, with higher prevalence in offender populations than in the general population. Previous research has strongly advocated increased awareness of TBI in offender populations. The aim of this study was to explore the prevalence and characteristics of TBI, and to investigate associations and interactions
Background: Postnatal insulin-like growth factor-1 (IGF-1) replacement with recombinant human (rh)IGF-1 and IGF binding protein-3 (rhIGF-1/rhIGFBP-3) is being studied as a potential treatment to reduce comorbidities of prematurity. We have recently reported on a phase II, multicenter, randomized, controlled trial comparing postnatal rhIGF-1/rhIGFBP-3 replacement with standard of care (SOC) in extr
The Eurasian (née European) Modern Pollen Database (EMPD) was established in 2013 to provide a public database of high-quality modern pollen surface samples to help support studies of past climate, land cover, and land use using fossil pollen. The EMPD is part of, and complementary to, the European Pollen Database (EPD) which contains data on fossil pollen found in Late Quaternary sedimentary arch
Antimicrobial peptides are important players of the innate host defence against invading microorganisms. The aim of this study was to evaluate the activity of airway antimicrobial peptides against the common cystic fibrosis (CF) pathogen Pseudomonas aeruginosa, and to compare it to the emerging multi-drug resistant CF pathogens Achromobacter xylosoxidans and Stenotrophomonas maltophilia. Clinical
Objective: Neurological outcome prediction is crucial early after cardiac arrest. Serum biomarkers released from brain cells after hypoxic-ischaemic injury may aid in outcome prediction. The only serum biomarker presently recommended in the European Resuscitation Council prognostication guidelines is neuron-specific enolase (NSE), but NSE has limitations. In this study, we therefore analyzed the o
Weather influences both the distribution and life-history strategies of birds. Temperature ranks amongst the more important weather parameters in this regard since warming springs in temperate and high latitudes and more frequent heat-waves globally have caused major changes in breeding phenology and negatively affected adult and juvenile survival, respectively. Both long-term and stochastic chang
Purpose: To assess the performance of a 4-step algorithm for neurological prognostication after cardiac arrest recommended by the European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM). Methods: Retrospective descriptive analysis with data from the Target Temperature Management (TTM) Trial. Associations between predicted and actual neurological outcome wer
This work is a part of the evaluation of a novel technique for carbon capture that can be used for CCS (carbon capture and storage) in industry. The technique is based on chemical amine absorption and involve the sterically hindered amine 2-amino-2-methyl-1-propanol (AMP) in an organic solvent, N-methyl-2-pyrrolidone (NMP). The systems have shown promising potential for carbon dioxide removal beca
International Journal of Molecular Medicine ISSN 1107-3756
INTRODUCTION: Using Swedish nationwide registry data, we investigated the contribution of genetic and environmental risk factors to the etiology of smoking status across stages of pregnancy with increasing degrees of social and psychological pressure to reduce or quit smoking, by twin and sibling modeling. AIMS AND METHODS: Smoking status was available before, and during early and late pregnancy f
By a combination of Monte Carlo simulations and analytical calculations, we investigate the effective interactions between highly charged planar interfaces, neutralized by mobile counterions (salt-free system). While most previous analysis have focused on pointlike counterions, we treat them as charged hard spheres. We thus work out the fate of like-charge attraction when steric effects are at wor
Climate change and increased urban population are two major concerns for society. Moving towards more sustainable energy solutions in the urban context by integrating renewable energy technologies supports decarbonizing the energy sector and climate change mitigation. A successful transition also needs adequate consideration of climate change including extreme events to ensure the reliable perform
