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Background: Seasonal variation in glucose metabolism might be driven by changes in daylight. Melatonin entrains circadian regulation and is directly associated with daylight. The relationship between melatonin receptor 1B gene variants with glycemic traits and type 2 diabetes is well established. We studied if daylight length was associated with glycemic traits and if it modified the relationship

As the dimensions of a structure are decreased towards the nanometer scale, the mechanical response to loading deviates from what is observed macroscopically. This is due to a change in material properties stemming from the relative increase in number of surface atoms as compared to bulk atoms. Surface atoms lack some of their neighboring atoms, leading to a reorganization of the electron clouds a

A comprehensive coarse grain model (CGM) is applied to simulation of biomass steam gasification in bubbling fluidized bed reactor. The CGM was evaluated by comparing the hydrodynamic behavior and heat transfer prediction with the results predicted using the discrete element method (DEM) and experimental data in a lab-scale fluidized bed furnace. CGM shows good performance and the computational ti

CONCLUSIONS: The blood group antigen Vel has been one of immunohematology's greatest enigmas: the variation in antigen strength from one individual to another, the property of anti-Vel to readily hemolyze Vel+ red blood cells (RBCs), and the difficulty to screen for sufficient numbers of Vel- blood donors had made Vel a tough nut to crack. In 2013, a small, previously unknown protein called small

One challenge to synthetic biology is to design functional machines from natural building blocks, from individual amino acids up to larger motifs such as the coiled coil. Here we investigate a novel bipedal motor concept, the Bar-Hinge Motor (BHM), a peptide-based motor capable of executing directed motion via externally controlled conformational switching between a straight bar and a V-shaped hin

This study applies a systematic literature review and qualitative content analysis to identify and synthesize key factors that enable collaborative innovation between industry and universities. Using a keyword search in the Web of Science database, the review identified 40 papers that were frequently cited on the topic. Results were summarized into seven main themes or central factors stimulating

Although experimental evidence indicates that certain organochlorine insecticides are hepatocarcinogens, epidemiologic evidence for most of these chemicals is very limited. We estimated associations, using prospectively collected sera, between organochlorine insecticide concentrations and cancer registry-identified primary liver cancer in two cohorts, one from the United States and one from Norway

Context: Chronic breathlessness is a cardinal symptom in cardiopulmonary disease where both overall intensity or severity (S) and unpleasantness (U) are commonly quantified. Objective: We aimed to evaluate agreement between breathlessness severity and unpleasantness over eight days in patients with chronic breathlessness. Methods: Longitudinal analysis of 265 patients with chronic breathlessness w

An experimental test system including the oil circulation system and the gas circuit system has been designed and built to explore the effects of the lubricating oil flow rate on the performance of a single-screw compressor, used in a portable natural gas liquefaction process. Outlet pressure, outlet volumetric flow rate, volumetric efficiency, and specific power rate are the parameters for evalua

This paper summarizes the state-of-the-art of the lattice matched GaInP/Ga(In)As/Ge triple-junction solar cell developed at the Solar Energy Institute of UPM (IES-UPM). Different research topics tackled over the last years about this structure are described. As result of this work, an efficiency of ∼ 40% at ∼ 415 × is presented.

We present a low-temperature electrical transport study on four-terminal ballistic InAs nanowire cross-junctions in magnetic fields aligned perpendicular to the cross-plane. Two-terminal longitudinal conductance measurements between opposing contact terminals reveal typical 1D conductance quantization at zero magnetic field. As the magnetic field is applied, the 1D bands evolve into hybrid magneto

This article deals with an essential problem in the metal cutting industry, the problem of predicting tool wear and tool life. This is also a problem that has been studied by academia for the last century, often with very little added knowledge. The possibility to replace a large number of systematic wear tests with only a few specially designed tests provides new potentials for rapid information