Do genetic risk profiles for drug use disorder (DUD), major depression (MD), and attention-deficit hyperactivity disorder (ADHD) differ substantially as a function of sex, age at onset (AAO), recurrence, mode of ascertainment, and treatment? Methods Family genetic risk scores (FGRS) for MD, anxiety disorders, bipolar disorder, schizophrenia, alcohol use disorder, DUD, ADHD, and autism-spectrum dis

This article discusses the phenomenon of normative resilience, with a focus on evaluative resilience. An object can become more or less valuable. In addition to this change in an object's value, the object's value can become more or less resilient. If it is less resilient, it cannot withstand as much evaluative change without its degree of value changing, as compared to an object with more resilie

Sensory feedback plays an important role in speech motor control. One of the main sources of evidence for this is studies in which online auditory feedback is perturbed during ongoing speech. In motor control, it is therefore crucial to distinguish between sensory feedback and externally generated sensory events. This is called source monitoring. Previous altered feedback studies have taken non-co

This paper proposes an iterative algorithm to reconstruct missing samples from non-stationary signals. The proposed algorithm is based on the well-known amplitude-modulation frequency-modulation model for non-stationary signals. The method initially estimates the instantaneous frequencies of the observed multi-component signal. The estimated IFs are then used to de-chirp the corresponding componen

The present study aims to describe accelerometer-assessed physical activity (PA) patterns and fulfillment of PA recommendations in a large sample of middle-aged men and women, and to study differences between subgroups of socio-demographic, socio-economic, and lifestyle-related variables. A total of 27 890 (92.5% of total participants, 52% women, aged 50–64 years) middle-aged men and women with at

Issues of sustainability, resilience, and risk management are linked to how the tourism industry and researchers respond to future ICT risk, known as “the year 2038 problem” (Y2K38). The tourism industry coped with similar but smaller risk, the Y2K “millennium bug” but lessons have not been learned. The paper presents an account of the lack of preparedness to ICT bugs and concludes that a cycle of

The term “the value of the child” was coined by economists in the context of demographic transition and fertility, emphasizing economic and cultural aspects. However, the scope of the value of the child was confined to a cost-benefit analysis. The “social value of the child” is a comprehensive concept that encompasses the economic, psychological, social, and cultural value of the child. Contextual

Introduction: Allergen exposure worsens viral-triggered asthma exacerbations and could predispose the host to secondary bacterial infections. We have previously demonstrated that exposure to house dust mite (HDM) reduced TLR-3-induced IFN-β in human bronchial epithelial cells (HBECs) from healthy donors. We hypothesize that HDM sensitization in different ways may be involved in both viral and bact

To increase the reliability and comparability of vocal loading studies, this paper proposes the use of a standardized approach with experiments that are [1] grounded on consistent definitions of terms related to vocal fatigue (vocal effort, vocal demand, and vocal demand response), and [2] designed to reduce uncertainty and increase repeatability. In the approach, a semi-automated vocal loading ta

Nicotine users are at greater risk of developing alcohol dependence. Conversely, alcohol is often consumed when young people test tobacco. The prevalence of smokers is high among alcohol dependent individuals and people who overconsume alcohol get more nicotine withdrawal symptoms when trying to quit tobacco and are less likely to succeed. Alcohol as well as smoking provides a high burden of disea

Begreppet hållbarhet har vuxit fram och etablerats sedan 90-talet. Eftersom näringslivet står för lejonparten av teknologiutvecklingen och investeringarna i ekonomin sägs ofta att företagens hållbarhetsarbete är centralt för att minska klimatpåverkan och för att kunna uppnå FN:s miljömål. I denna studie undersöks hur representationer av hållbarhet vuxit fram i svenska företag genom analyser av års

Artikeln behandlar ett återkommande språkligt mönster i idrottstränares instruktioner och återkoppling till tränande barn. Mönstret utgörs av ett tvåledat yttrande där ett instruerande led föregås av ett orienterande led med lägre informationsvärde och en delvis annan funktion. I artikeln beskrivs detta orienterande led som scene-setting, vilket syftar på att den orientering som föregår och förber

The ripeness of fruits is commonly assessed by the visual appearance, but this method is not very accurate and there can be a large variability. We have developed a hand-held sensor based on laser-induced fluorescence to provide more objective guidance. The instrument incorporates a 412 nm continuous wave semiconductor laser and a miniature spectrometer. It was used for monitoring of tropical frui

Kubernetes (K8s) is one of the best options available to deploy applications in large-scale infrastructures. Security has been a big concern for all practitioners in the K8s eco-system. Almost all cloud vendors have their security solution for K8s cluster, pods, workloads, etc. In recent years, a large number of open-source tools and projects related to K8s security have emerged to meet the increa

Leucism, broadly defined as the lack of melanin pigmentation, occurs in many animal species. Most studies on leucism and other colour aberrations are based on opportunistic observations or small cross-sectional samples, thus limiting our ability to produce reliable results and test theoretical predictions. This study combines cross-sectional and longitudinal data collected in 2016–2020 from a popu

Background/Objective: The frequencies of non-susceptibility against common antibiotics among pneumococci vary greatly across the globe. When compared to other European countries antibiotic resistance against penicillin and macrolides has been uncommon in Sweden in recent years. Multidrug resistance (MDR) is, however, of high importance since relevant treatment options are scarce. The purpose of th