Effects of phosphorylation on the ADP-ribosylation activity of PARP16
PARP16/ARTD15 is an intracellular mono-ADP-ribosyltransferase that catalyzes auto- and heteromodification by transfer of a single ADP-ribose moiety. It belongs to the ADP-ribosyltransferase (ART) superfamily. ADP-ribosylation of amino acids on protein targets is critical in the regulation of cellular pathways in eukaryotes, especially involved in physiological functions, cell stress responses and