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Negative Pressure Wound Therapy - Effects on Sternotomy Wounds and the Intrathoracic Organs

Popular Abstract in Swedish Bakgrund En till fem procent av de patienter som genomgår öppen hjärtkirurgi får en efterföljande infektion i operationssåret och bröstbenet. Infektionen kan leda till allvarliga komplikationer såsom blodförgiftning, organsvikt och i värsta fall till att patienten avlider. De traditionella metoder som används för att behandla den här typen av infektion har visat sig haNegative pressure wound therapy (NPWT) has been widely adopted for the treatment of deep sternal wound infections due to its excellent clinical outcome. However, the mechanisms of action and effects on hemodynamics have not been thoroughly elucidated. The aims of the work presented in this thesis were, therefore, to examine the effects of NPWT on sternotomy wounds and on the intrathoracic organs.

Using computed tomography and digital radiography of the human body to visualize metal fragments from bomb explosions – A preliminary report

A thoracic phantom, with embedded fragments of uranium (U) and iron (Fe) of different sizes, was imaged with digital radiography, standard-dose CT and low-dose CT and the detectable size of the fragments was recorded. U and Fe fragments were detected in diameters down to 100 mu m and 300 mu m, respectively with the standard-dose CT and digital radiography. The size limit using the low-dose CT was

Targeting human papillomavirus to reduce the burden of cervical, vulvar and vaginal cancer and pre-invasive neoplasia: establishing the baseline for surveillance.

Infection with high-risk human papillomavirus (HPV) is causally related to cervical, vulvar and vaginal pre-invasive neoplasias and cancers. Highly effective vaccines against HPV types 16/18 have been available since 2006, and are currently used in many countries in combination with cervical cancer screening to control the burden of cervical cancer. We estimated the overall and age-specific incide

Single-particle and collective excitations in Ni-63

A study of excited states in Ni-63 up to an excitation energy of 28 MeV and a probable spin of 57/2 was carried out with the Mg-26(Ca-48,2 alpha 3n gamma)Ni-63 reaction at beam energies between 275 and 320 MeV. Three collective bands, built upon states of single-particle character, were identified. For two of the three bands, the transition quadrupole moments were extracted, herewith quantifying t

Magneto-Transport Characterization of Four-Arm Nanostructure Based on Ferromagnetic (Ga,Mn)As

We report on results of magneto-transport measurements performed on four-arm nanostructure fabricated from p-type ferromagnetic Ga0.92Mn0.08As layer. The results reveal hysteresis-like behaviors of low field magneto resistance. We interpret the magnetoresistance in terms of domain walls, which are expected to be trapped inside the nanostructure at some particular positions and which contribute to

Amorphous Silica Preservation in an Anthropogenic Soil: An Explorative Study of "Plaggen" Soils

Amorphous Silica (ASi) is present in considerable amounts in most soils and serves as a (micro-)nutrient for many plants. However, our understanding of the response of this important nutrient pool to human or natural disturbances is still very limited. One of the reasons for this is the long time scales involved. This explorative study focuses on the effect of a historical agricultural system, cal

Do drug transporter (ABCB1) SNPs and P-glycoprotein function influence cyclosporine and macrolides exposure in renal transplant patients? Results of the pharmacogenomic substudy within the symphony study

The function of the efflux pump P-glycoprotein (Pgp) and ABCB1 single nucleotide polymorphisms (SNPs) should be considered as important tools to deepen knowledge of drug nephrotoxicity and disposition mechanisms. The aim of this study is to investigate the association of C3435T, G2677T, C1236T, and T129C ABCB1 SNPs with Pgp activity and exposure to different immunosuppressive drugs in renal transp

An Approach to Analyze the Movements of the Arms while Walking using Wearable Wireless Devices

Abstract—Rhythmic movement of the arms while walking is an important feature of human gait. In this paper, we present an approach to analyze the movements of the arms while walking by using three wearable wireless devices placed around the torso. One of the devices is transmitter placed at the back and the other two are symmetrically placed receivers that record the power variation due to movement

14C and 10Be around 1650 cal BC

There is a debate about the date of the Minoan eruption of Santorini as reconstructed from a branch of an olive tree that was buried alive in trephra on Santorini2 and the dating of an ice core horizon attributed to this eruption.3 The olive branch was 14C-wiggle matched to the 14C calibration curve and yielded an age range of 1627-1600 bc4 while the counting of annual layers in the Greenland ice

Oscillator strengths for lines of astrophysical interest in Rh II

Aims. This work reports oscillator strengths for transitions of astrophysical interest in singly ionized rhodium. Methods. Seventeen radiative lifetimes in Rh+ have been measured with the time-resolved laser-induced fluorescence technique and combined with theoretical branching fractions calculated using a relativistic Hartree-Fock model including core-polarization effects to obtain oscillator str

Management intensity at field and landscape levels affects the structure of generalist predator communities

Agricultural intensification is recognised as a major driver of biodiversity loss in human-modified landscapes. Several agro-environmental measures at different spatial scales have been suggested to mitigate the negative impact of intensification on biodiversity and ecosystem services. The effect of these measures on the functional structure of service-providing communities remains, however, large

Investigation of different valve geometries and valve timing strategies and their effect on regenerative efficiency for a pneumatic hybrid with variable valve actuation

In the study presented in this paper a single-cylinder Scania D12 diesel engine has been converted to work as a pneumatic hybrid. During pneumatic hybrid operation, the engine can be used as a 2-stroke compressor for generation of compressed air during vehicle deceleration and during vehicle acceleration the engine can be operated as an air-motor driven by the previously stored pressurized air. T

Influence of strut inertia on the vibrations in initially symmetric Gough-Stewart Platforms-an analytical study

Consideration of strut inertia can have significant influence on the modal behavior of a Gough-Stewart Platform (GSP). However, in the literature, the strut inertia has not yet been taken into account in its vibration study with a parametric approach. In this paper, we present a fully parametric approach to formulate the damped vibrations of GSPs taking into account the strut masses and moments of