Filtyp
A Palaeolithic diet is an efficacious dietary approach for glycaemic control in type 2 diabetes. Causal mechanisms are body weight loss and glucometabolic effects from differences in included food groups, macronutrient composition, fibre content, and glycaemic load. The aim was to test the hypothesis that characteristic food group differences between a Palaeolithic and a diabetes diet would cause
BACKGROUND: Brain-derived neurotrophic factor (BDNF) plays a critical role in neuronal development and neural connectivity, and has been implicated in the pathophysiology of Major Depressive Disorder (MDD). However, its predictive value for MDD onset remains unclear. This study examined whether baseline BDNF levels are associated with incident MDD in middle-aged women.MATERIAL AND METHODS: In this
Pedagogical development programmes (PDPs) are important for developing teaching skills for university teaching staff. Due to participants’ different teaching roles, their professional development needs and interests may also be different. However, little is known regarding the immediate needs of university teaching staff when they enter PDPs and how these may differ according to their roles. This
Smart city control rooms are prominent components of the smart city discourse. They embody a long- standing dream to visualize and manage multiple urban processes in real time through the collation of data flows. Previous research has produced important insights into the design, construction and operation of these facilities. However, this research has largely overlooked the fundamental changes t
Lost Farm Festival forvandlede en nedlagt gård til et globalt samlingspunkt for sorg, vrede og skaberkraft – hvor koncerter, ritualer og installationer gjorde Sjællands Odde til et nyt midtpunkt for verden.Lost Farm Festival transformed an abandoned farm into a global gathering point for grief, anger and creativity – where concerts, rituals and installations turned Sjællands Odde into a new center of the world.
BackgroundThe purpose was to evaluate the prognostic impact of aryl hydrocarbon receptor (AHR) genotypes in relation to lifestyle and adjuvant treatments in breast cancer.MethodsAHR genotyping was performed on genomic DNA from 1701 patients included 2002–2016 in Lund, Sweden, and followed for up to 15 years. Eight AHR polymorphisms and eight haplotypes were analysed using survival and interaction
Disruptions in circadian rhythm, partly controlled by the hormone melatonin, increase the risk of type 2 diabetes (T2D). Accordingly, a variant of the gene encoding the melatonin receptor 1B (MTNR1B) is robustly associated with increased risk of T2D. This single-nucleotide polymorphism (SNP; rs10830963; G-allele) is an expression quantitative trait locus (eQTL) in human pancreatic islets, conferri
Background: Prolactin receptor (PRLR) signaling affects breastfeeding and potentially breast cancer treatment response. Methods: The prognostic impact of 20 PRLR single nucleotide polymorphisms (SNPs) in relation to adjuvant treatment groups in patients with primary breast cancer (n = 1701, 2002–2016, Sweden) was evaluated. Genomic DNA was genotyped on Illumina OncoArray, and survival analyses wit
The effects of high hydrostatic pressure (up to 8 kbar) on bacteriochlorophyll a Qy electronic absorption bands of LH2 photosynthetic antenna complexes have been studied at ambient temperature. A variety of samples were studied, including intact membranes and isolated complexes from wild type and mutant photosynthetic bacteria Rhodobacter sphaeroides, Rhodopseudomonas acidophila, and Rhodospirillu
The ultrafast energy transfer among the pigments of the B800-850 membrane antenna pigment-protein complex of the photosynthetic purple bacteria Rhodobacter sphaeroides and Rhodopseudomonas palustris LL has been studied with ≈ 100 fs tunable infrared pulses at room temperature and 77 K. It is shown that the B800→B850 transfer time is similar in both species and occurs with a characteristic time con
Previous work has suggested that the βArg-10 residue forms part of the binding site for the B800 bacteriochlorophyll in the LH2 complex of Rhodobacter sphaeroides [Crielaard, W., Visschers, R. W., Fowler, G. J. S., van Grondelle, R., Hellingwerf, K. J., Hunter, C. N. (1994) Biochim. Biophys. Acta 1183, 473−482], and this is consistent with the X-ray crystallographic data that have been subsequen
In order to understand the origin of ultrafast carotenoid bandshifts upon photoexcitation of bacteriochlorophyll (BChl) molecules in antenna complexes of photosynthetic purple bacteria, we have performed sa-CASSCF(8,7)/6-31G (and 6-31G*) calculations for the low-lying excited states of the carotenoid rhodopin glucoside (RG). The LH2 environment was simulated via atomic point charges to represent t
The picosecond time-domain incoherent singlet excitation transfer and trapping kinetics in core antenna of photosynthetic bacteria are studied in case of low excitation intensities by numerical integration of the appropriate master equation in a wide temperature range of 4–300 K. The essential features of our two-dimensional-lattice model are as follows: Förster excitation transfer theory, spectra
The excitation annihilation and anisotropy kinetics in the B850 ring were studied. As a result, a new insight into the problem of exciton coherence in photosynthetic light harvesting was obtained.
A central function of human cognition is the ability to perceive, understand, and remember life experiences as meaningful sequences of discrete events. This process, known as event segmentation, allows individuals to spontaneously construct and update event models and has been shown to engage a distributed network of brain regions that transiently increase in activity at event boundaries (e.g., Za
We review concepts and recent work related to creating light-matter interfaces for future quantum networks based on rare-earth ion-doped crystals. More precisely, we explore their unique suitability for creating photon sources, optical quantum memories for light, and qubits that allow quantum information processing. In addition, we review the state-of-the-art of elementary quantum repeater links,
This thesis investigates the spectral properties of magnetic and nonmagnetic Schrödinger operators, which haveapplications in the distribution of superconductivity in type II superconductors and wave theory. The thesis beginswith an introduction to the main results in the field, giving a more detailed presentation for clarity. Next, we focuson the original research articles conducted by the author
We develop a framework for categorization in games, applicable both to multistagegames of complete information and static games of incomplete information.Players use categories to form coarse beliefs about their opponents’behavior. Players best-respond given these beliefs, as in analogy-based expectationsequilibria. Categories are related to strategies via the requirementsthat categories contain a
Objective: To overview and summarise the Swedish National Guidelines on Urothelial Carcinoma 2024. Methods: A narrative review of the updated guidelines was performed, highlighting new treatment recommendations for advanced and metastasized disease. Results: Compared to the previous guideline version, the current update includes recommendations for standardised radiological reporting when urotheli
Spectral imaging allows for the simultaneous visualization of multiple different spectral bands of a scene, and is a powerful tool used in a range of contexts - from the color cameras in smart phones, to scientific imaging applications such as remote sensing and fluorescence microscopy. The progress within these fields of research is therefore intrinsically linked to the advances made for more eff
