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The goal of this research is to use hematopoietic cells as vehicles for targeting transgenic immunomodulators to the inflammatory sites. The work presented was focused on the anti-inflammatory soluble TNF receptor. A transmembrane soluble TNF receptor (sTNFR1) construct was expressed in hematopoietic cell lines. ER export was facilitated by addition of a transmembrane (tm) sequence, and constituti

Education is the foundation for achieving sustainable development. The United Nations Decade of Education for Sustainable Development declared from January 2005 to December 2014 demands a concerted effort to expand environmental education around the world. The Young Masters Program is an international education course, which utilises the internet to connect students, teachers, and tutors in differ

The aim of this study was to investigate determinants of help from informal or formal caregivers or a combination of both among people aged 75 or more and living at home, and the characteristics of the recipients, the help they received and their quality of life (QoL). The sample for this study was 448 elderly people, 75-99 years of age, living at home and receiving help with activities for daily

In hydrological models for water resources management and planning, the model output or design quantities are functions of the input data and a number of parameters that are essentially stochastic processes or random variables. The task of uncertainty analysis is to estimate the uncertainty characteristics of the model output in terms of the uncertainties in the input, model parameters and initial

Women younger than 50 have a lower age-specific incidence of CVD than men. With advancing age this difference gradually disappears. These well-established facts provide the rationale for numerous primary and a few secondary intervention studies with ERT. With increasing sophistication and longer observation periods, both case-control and cohort studies agree on a cardioprotective effect by estroge

Popular Abstract in Swedish Avhandlingen består av tre uppsatser som behandlar empiriska tillämpningar av makroekonomiska teorier. Uppsatserna är fristående från varandra, men knyts samman genom att kointegrationsanalys används i de empiriska analyserna. Kointegrationsanalys är en statistisk metod som syftar till att hitta långsiktiga samband mellan olika variabler i ett empiriskt datamaterial. EfThis thesis focuses on empirical applications and tests of macroeconomic theories. It consists of three fairly distinct essays, bound together by the common theme of the use of cointegration analysis in the empirical macroeconomic analysis. The first chapter is an introductory chapter, while chapter two, three and four contain the three essays. The first essay, Wage Formation and the Relation bet

A 14C-dated magnetostratigraphy of absolute declination and inclination between 12500 and 10000 14C yr BP was recently developed for southern Sweden. Recently also the Swedish geochronological time-scale, based on c. 11 500 annually deposited clay-varves, was connected with the present. It should therefore be possible to compare the two chronologies with a reliable magnetostratigraphic record in a

Popular Abstract in Swedish Yrsel är ett mycket vanligt symtom bland patienter inom olika specialiteter inom sjukvården. Orsaken bakom symtomen kan ligga i neurologiska sjukdomar, sjukdomar i innerörats balansorgan samt i psykiatriska sjukdomar, framför allt ångestsjukdomar. Medicinska undersökningar leder inte alltid till att orsaken till yrseln konstateras i en specifik sjukdom och ibland kan maDizziness is a common problem and it often co-exists with anxiety. Level of anxiety is the best predictor of handicap for dizzy patients. There is diagnostic controversy and few treatment programs for such patients. These patients can be labeled as panic disorder with agoraphobia or by the concept of Phobic Postural Vertigo which is characterized by dizziness or imbalance in standing or walking de

During pregnancy and lactation, changes occur in a variety of factors which have great potential to influence bone mineral density (BMD). Smoking habits, the level of alcohol consumption, the level of physical activity, body weight, soft tissue composition and hormone levels are all factors that change during the course of these conditions. Some of these factors are capable of increasing BMD, and