En av de sjukdomar som påverkar flest människor årligen är malaria. Malaria sprids av myggor som bär på parasiten och när de biter en människa överförs parasiten till människan. Vanliga symptom vid en malariainfektion är lätt feber, frossa och huvudvärk. Dessa symptom kan bli allvarligare om personen är gravid, ett barn mindre än fem år gammalt, eller har HIV eller AIDS, eftersom sådana personer tMalaria is a well-known disease and affects large regions around the world. Medicines used for treatment already exist, but due to increasing resistance and unpleasant side effects it has become critical to develop new drug candidates. Several palladium complexes were synthesised and studied to understand their properties for treating malaria. The ligands and the complexes were synthesised and cha

The higher education sector has been massively disrupted by COVID-19. The technological changes of the past two decades have enabled a ‘blended learning’ approach. Nonetheless, most academics were not prepared to become fully online teachers with very short notice (nor were most students prepared to learn online) in 2020. Our aim was to investigate and document changes in teaching from the perspec

Contemporary research observes how foreign information influence present a governing challenge for liberal democratic states. Less attention has been paid to how this governing dilemma emerged in its present form. This article outlines a genealogy of the longstanding Swedish strategy of psychological defence with the aim of tracing historical trajectories of liberal democratic thinking about infor

This paper examines seasonal migrant farmworkers in Turkey, focusing on the intersection of relations of production and social reproduction under rapidly shifting land and labour regimes. The workers are predominantly Kurds and Arabs of Turkey and Syrian refugees, and experience the intersecting crises of neoliberalism, rural-urban migration and conflict/disaster displacement in amplified ways. Wi

In this thesis, we study modeling approaches for the Cahn-Hilliard equations utilizing the Eyre approximation for first and second order in time accuracy. We first considered the Cahn-Hilliard equations and then expand our study by adding the Navier-Stokes coupling. We begin with a study concerning preconditioners, grid size options, mobility functions, energy density discretization, and time-step

Traumatic brain injury (TBI) often leads to impaired regulation of cerebral blood flow, which may be caused by pathological changes of the vascular smooth muscle cells (VSMCs) in the arterial wall. Moreover, these cerebrovascular changes may contribute to the development of various neurodegenerative disorders such as Alzheimer’s-like pathologies that include amyloid beta aggregation. Despite its i

Denna studie undersökte sambandet mellan altruism, extraversion och motivation. Ett av personlighetsdragen i femfaktorsmodellen är extraversion. Detta personlighetsdrag testades som en möjlig prediktor för altruistiskt beteende. Dessutom undersöktes motivation som en ytterligare faktor bakom altruism. Deltagarna (N = 68) besvarade en enkät från online bestående av tre självskattningsskalor. ExtravThis study examined the relationship between altruism, extraversion, and motivation. One of the personality traits in the five-factor model is extraversion. This personality trait was tested as a potential predictor of altruistic behavior. Additionally, motivation was investigated as another factor contributing to altruism. Participants (N = 68) completed a questionnaire from online consisting of

Accumulating research shows that maternal mental health during pregnancy is linked to early neurodevelopmental changes in the offspring. Yet, there is a gap in examining how multiple prenatal risk and resilience factors are associated with early brain development. Therefore, this study explored multiple maternal and paternal psychosocial factors during pregnancy, and their link to neonatal brain s

Rhythmicity is a composite competence that spans perceptual, motor, and socio-cognitive abilities. This is highly salient when adopting a developmental perspective, as we do in this chapter that reviews data from humans and other singing primate taxa with a close (gibbons) or remote (indri lemurs) phylogenetic relatedness to our species. The findings we review show that rhythmicity develops as an

We report on the influence of selected components and their mixtures on the development of the morphology during drying of single droplets and extend the results to the morphology of whole milk powder particles. Sessile single droplet drying and acoustic levitation methods were employed to study single droplet drying. The influence of carbohydrates (lactose and maltodextrin DE12) and proteins (mic

Liquid crystalline nanoparticles (LCNPs), e.g. cubosomes and hexosomes, are receiving more and more attraction as drug delivery vehicles. Dry powder formulation that forms LCNPs upon hydration can be advantageous to make new routes of administration accessible. In this work, we investigate use of three disaccharides (lactose, trehalose and sucrose) as protective matrices for glycerol monooleate ba

Preprocessing of pharmaceutical powders is a common procedure to condition the materials for a better manufacturing performance. However, such operations may induce undesired material properties modifications when conditioning particle size through milling, for example. Modification of both surface and bulk material structure will change the material properties, thus affecting the processability o

Dissolved organic carbon (DOC) affects the acidity in soil and lake waters and buffers both against acidification and against recovery from acidification. Current acidification assessments, based on the widely used MAGIC (Model of Acidification of Groundwater In Catchments) model, often assume constant DOC concentrations through time, but observations suggest this assumption may not be warranted.

Adhesion of the powders to the punches is a common issue during tableting. This phenomenon is known as sticking and affects the quality of the manufactured tablets. Defective tablets increase the cost of the manufacturing process. Thus, the ability to predict the tableting performance of the formulation blend before the process is scaled-up is important. The adhesive propensity of the powder to th

Two different food grade functionalised porous calcium carbonates (FCC), with different pore size and pore size distributions, were characterised and used as carrier materials to increase the dissolution rate of poorly soluble flavouring compounds in aqueous solution. The loading level was varied between 1.3% by weight (wt%) and 35 wt%, where the upper limit of 35 wt% was the total maximum loading

The nature of the surfaces of particles of pharmaceutical ingredients, food powders, and polymers is a determining factor for their performance in for example tableting, powder handling, or mixing. Changes on the surface structure of the material will impact the flow properties, dissolution rate, and tabletability of the powder blend. For crystalline materials, surface amorphization is a phenomeno