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EU and Regulatory Autonomy on the Digital Trade Frontier

Amid the rapid expansion of the global digital economy, the European Union faces a fundamental tension between promoting digital trade liberalisation and safeguarding its regulatory autonomy. This thesis examines how policy space provisions within the EU's new, standalone Digital Trade Agreements (DTAs) with Singapore and South Korea relate to this strategic challenge. Using a legal doctri-nal

Dimensionality reduction and prioritized exploration for policy search

Black-box policy optimization is a class of reinforcement learning algorithms that explores and updates the policies at the parameter level. This class of algorithms is widely applied in robotics with movement primitives or non-differentiable policies. Furthermore, these approaches are particularly relevant where exploration at the action level could cause actuator damage or other safety issues. H

Tousled-like kinases stabilize replication forks and show synthetic lethality with checkpoint and PARP inhibitors

DNA sequence and epigenetic information embedded in chromatin must be faithfully duplicated and transmitted to daughter cells during cell division. However, how chromatin assembly and DNA replication are integrated remains unclear. We examined the contribution of the Tousled-like kinases 1 and 2 (TLK1/TLK2) to chromatin assembly and maintenance of replication fork integrity. We show that TLK activ

Cloning, expression and production of Vicia faba Leghemoglobin B

Hemoglobin är ett viktigt protein. Det återfinns i röda blodkroppar och dess huvudfunktion är att transportera syre genom kroppen. Hemoglobin är komplext till sin struktur, till exempel består proteinet av fyra subenheter. I människor återfinns två varianter: vuxet och fetalt. Förmågan att binda syre, affiniteten, skiljer sig åt mellan dessa. I fetalt hemoglobin är syreaffiniteten högre än i vuxetIn this thesis a preliminary evaluation of the potential of a leghemoglobin (Lb) for the development of a blood substitute in humans, resembling hemoglobin (Hb) in red blood cells, was conducted. Leghemoglobin B (VfLbB), a gene from Vicia faba, was cloned into a pET-DEST42 vector, using the Gateway™ recombination technology. The recombinant vector containing VfLbB was sequenced and confirmed. Then

Encoding contexts are incidentally reinstated during competitive retrieval and track the temporal dynamics of memory interference

The ability to remember an episode from our past is often hindered by competition from similar events. For example, if we want to remember the article a colleague recommended during the last lab-meeting, we may need to resolve interference from other article recommendations from the same colleague. This study investigates if the contextual features specifying the encoding episodes are incidentally

Film as Autobiographical Essay; Mirror, Reenactments and Voice in The Beaches of Agnès (2008) by Agnès Varda

This thesis provides a formal analysis of Agnès Varda’s documentary The Beaches of Agnès (2008), focusing on how the formal elements in the film such as voice-over, reenactments and the use of mirrors create a sense of self-awareness in the film. Through Agnès Varda’s extensive body of work it is possible to see the historical movement of the essay film, from its relation to the French Cinema fro

Selective privatisation and changing civic spaces in India : The government takeover of an erstwhile NGO-run child helpline

Much scholarship has critiqued the fact that non-governmental organisations (NGOs), as a result of global neoliberalism and consequential state retreat, have become private service providers of children’s protection rights. But how can we explain the situation when neoliberal states also undergo autocratisation and take back service provision from NGOs, while at the same time preserving the privat

Tumour-infiltrating immune cells in tonsillar cancer : no tissue-level signs of inflammageing in the elderly

Background: Age-related immunosenescence, also known as ‘inflammageing’, may impact the elderly’s ability to mount immune responses against cancers and compromise the effectiveness of immune checkpoint inhibition (ICI). In this context, data on tonsillar cancer (TC), a subset of head and neck squamous cell cancer (HNSCC), are lacking. Aims/objectives: To compare the presence/distribution and featu

Prototype of Image Preprocessing and Analysis System Supporting UAV Camera Guidance

This work presents the architecture of a prototype software system for image preprocessing and analysis designed to support the guidance of an auxiliary UAV camera. The study begins with an overview of typical UAV onboard elec-tronics, highlighting the electro-optical equipment, which includes a navigation camera and an auxiliary camera with a narrower field of view. Automatic image analysis from

Covalent Stabilization of Collagen Mimetic Triple Helices and Assemblies by Dopa Crosslinking

Creating thermally stable collagen mimetic peptides (CMPs) is a persistent challenge. Nature leverages covalent crosslinkings to stabilize collagen's signature triple helical tertiary structure and higher-order assemblies. Herein, crosslinkings between levodopa (Dopa) and lysine can covalently stabilize the triple helix in CMPs is demonstrated. Since alkaline conditions catalyze the oxidation of t

Camp : a modular metagenomics analysis system for integrated multistep data exploration

Computational analysis of large-scale metagenomics sequencing datasets provides valuable isolate-level taxonomic and functional insights from complex microbial communities. However, the ever-expanding ecosystem of metagenomics-specific methods and file formats makes designing scalable workflows and seamlessly exploring output data increasingly challenging. Although one-click bioinformatics pipelin

Conflictualization : Theorizing how relations, societies, and issues come to be formed by the logic of conflict

This article presents a Luhmann-inspired theory of conflictualization, that is, how objects, relations, and societies come to be defined by the logic of conflict. This article presents a Galtung- and Luhmann-inspired theory of conflictualization, that is, how objects, relations, and societies come to be defined by the logic of conflict. The article conceptualizes conflictualization as a threefold

Det "upphävbara" gynnande förvaltningsbeslutet - En analys av lagförslaget om att återkalla det svenska medborgarskapet i relation till gynnande förvaltningsbesluts orubblighet

Uppsatsen behandlar och analyserar delar av lagförslaget om återkallelse av svenskt medborgarskap som presenteras i 2023-års fri- och rättighetskommittés betänkande Några frågor om grundläggande fri- och rättigheter (SOU 2025:2). Fokus ligger på förhållandet mellan orubblighetsprincipen hos gynnande förvaltningsbeslut och den föreslagna återkallelsemöjligheten, samt på tolkningen av rekvisiten ”or

Exploring optimal expression conditions for low-degraded and low chaperone-contaminated recombinant silk protein

Spider silk is a highly attractive biomaterial with exceptional strength and versatility, offering potential applications across numerous industries. However, large-scale production remains a significant challenge. Harvesting silk directly from spiders has proven impractical, making recombinant protein production a promising alternative. Spider silk has been studied at Lund University for several