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5-Azacitidine (AZA) therapy is used in high-risk myelodysplastic syndrome (MDS) patients who often show abnormalities in their immunophenotype. We explored the potential impact of AZA on these immunophenotypic abnormalities in serial bone marrow studies performed in 81 patients from five centers. We compared the immunophenotypic features before and after therapy with AZA, established definitions c

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A hybrid sodium heat pipe receiver has been developed within the project HYHPIRE, funded 50% by the European Commission. The hybrid receiver was designed for the SBP/LCS 10-kWel dish/Stirling system with the SOLO-161 Stirling engine. Design of the heat pipe receiver and combustion system are described in this paper The system has been tested successfully in all operation modes. Results and experie

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Functionalities of clay-polymer nanocomposites (CPN) are related to the degree of clay particle exfoliation and orientation within the polymer matrix. Exploration of new physical methods for such CPN processing is currently an active field of research. In the present work, organoclay polypropylene nanocomposites were prepared by melt intercalation and subsequently exposed to an electric field (E)

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SLF’s vårexkursion gick till trakterna av Kumla och Örebro med Mikael Hagström som arrangör. En god skara människor hade slutit upp och trotsade de initialt urusla vädret, men som tur var bättrade det sig. Med på exkursionen var Martin Westberg, Samantha Fernandez Brime, Ulf Arup, Emil Persson, Sten Svantesson, Stefan Ekman, Linnea Eide-Ekman, Måns Svensson, Lovisa Fogelberg, Ola Hammarström, Jesp

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EU criminal justice is a fast developing and challenging area of EU law and policy that requires scholars from different disciplines to join forces. This book is a first attempt to establish such synergies. Coming from different angles, the authors deal with questions in the area of EU substantive criminal law, such as when criminalisation of conduct is an appropriate choice; how the process of (d

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Tau protein neurofibrillary tangles are closely linked to neuronal/synaptic loss and cognitive decline in Alzheimer's disease and related dementias. Our knowledge of the pattern of neurofibrillary tangle progression in the human brain, critical to the development of imaging biomarkers and interpretation of in vivo imaging studies in Alzheimer's disease, is based on conventional two-dimensional his

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Since vitamin B6 is essential for normal functioning of the central nervous system, there is growing need for sensitive analysis of B6 vitamers in cerebrospinal fluid (CSF). This manuscript describes the development and validation of a rapid, sensitive and accurate method for quantification of the vitamin B6 vitamers pyridoxal (PL), pyridoxamine (PM), pyridoxine (PN), pyridoxic acid (PA), pyridoxa

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A plethora of methods exist to aid decision-making in mitigating disaster risk, many of which fall into the categories of risk, vulnerability and/or resilience assessment methods. The objective of the present study is to provide an overview of these methods, with a particular focus on evidence that supports their practical implementation. A scoping study of scientific literature reveal 97 distinct