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Evidence is presented for a new pathway participating in anterior neural development. It was found that IGF binding protein 5 (IGFBP-5), as well as three IGFs expressed in early embryos, promoted anterior development by increasing the head region at the expense of the trunk in mRNA-injected Xenopus embryos. A secreted dominant-negative type I IGF receptor (DN-IGFR) had the opposite effect. IGF mRN
A black box in the study of representation in European democracies is our knowledge about elected but also unelected candidates. What is their background? How are they recruited? What are their campaign aims, strategies, resources and tools? How do they relate to their (constituency and central) party and their voters? How do they consider democratic governance at national and European levels? Thi
The Eigenfactor™ is a journal metric, which was developed by Bergstrom and his colleagues at the University of Washington. They invented the Eigenfactor as a response to the criticism against the use of simple citation counts. The Eigenfactor makes use of the network structure of citations, i.e. citations between journals, and establishes the importance, influence or impact of a journal based on i
National apologies are offered by a political representative of the state to members of a minority group for the historic wrongs they suffered within that state. They are used as a reparation measure to further reconciliation, to build mutual confidence and to create a shared identity in a society divided by historic human rights violations. They are a part of the right to remedy for victims of gr
One of the main contributors in the immune system are T cells. The exact molecular mechanisms behind T cell activation are not yet fully understood but it starts through the contact between the T cell and an infected cell. In order to study such interaction, supported lipid bilayers (SLBs) are used to mimic cell membranes and to reduce its complexity but still retaining the fundamental property of
The main aim of this study is to contribute to the existing gap regarding the combination of green marketing and B2B marketing. Building on this, the focus of this paper is to investigate critically the relevance of sustainability labels for products in industrial markets and to find alternative practices that companies can implemented to build up trust and obtain credibility. The choice of the in
Our problem considered was whether a virtual environment could be used for development of visual servoing control algorithms.
We have used a virtual environment for the comparison of several kinds of controllers. The virtual environment is done in Java, and it consists of two industrial robots, IRB 2000 and IRB 6, a camera stereo system with two cameras mounted on the end-effector of the IRB 6,
In this report the preparation of colloidal molecules through electrostatically driven self-assembly of spherical, thermoresponsive microgel building blocks is investigated. Colloidal molecules are of interest to the scientific community because, unlike spherical colloids, they account for anisotropic interactions that can also be found in atomic molecules. The added benet of using thermoresponsiv
The Tröger’s base molecule has a unique V-shaped cavity and can be fused together in a linear fashion to create either tubular structures or zigzag structures. These structures could be applicable in for example catalysis. The Tröger’s base scaffold is easily functionalised with different side-groups and therefore has a wide range of applications. Previous research in the Wärnmark group had led to
The genetic regulation of hematopoietic stem and progenitor cells (HSPCs) plays a vital role in the development and function of the immune and circulatory systems. Genetic variants can lead to significant differences in HSPC-related phenotypes, and pathogenic variants can cause blood disorders and other maladies. Discovering these variants and understanding the mechanisms by which they affect an i
