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GTP-cyclohydrolase deficiency in dopa-responsive dystonia (DRD) patients impairs the biosynthesis of dopamine, but also of serotonin. The high prevalence of non-motor symptoms suggests involvement of the serotonergic pathway. Our study aimed to investigate the serotonergic system in vivo in the brain of`DRD patients and correlate this to (non-)motor symptoms. Dynamic [11C]DASB PET scans, a marker
Mänsklig aktivitet i buffertzonen på Cypern gör det nödvändigt att för det första utveckla en tydlig förståelse av detta områdes folkrättsliga status och för det andra i möjligaste mån besvara spörsmål om vem som har det folkrättsliga ansvaret där. Före-varande studie behandlar dessa frågor i tre delar: - Kapitel 2 ger en kort beskrivning av buffertzonen och dess historia, från dess inrättande
Brevmall A. Reading course in Classical anthropological theory (PhD level) A third level (PhD) “reading course” does not involve any teaching and typically only has one or a few participants taking part in the course. A reading course for 7,5 credits should cover an ambitious and demanding reading material, which exact page number can vary depending on the nature of texts (i.e., heavy dominance of
https://www.soc.lu.se/en/sites/soc.lu.se.en/files/2024-02/Classical%20anthropological%20theory.pdf - 2026-07-22
Factor I (FI) is one of the main inhibitors of complement activity, and numerous rare coding variants have been reported in patients with age-related macular degeneration, atypical hemolytic uremic syndrome and C3 glomerulopathy. Since many of these variants are of unknown clinical significance, this study aimed to determine the effect of rare coding variants in the complement factor I (CFI) gene
BACKGROUND: Hypoglycemia is one of the most common metabolic derangements in childhood. To establish the cause of hypoglycemia, fasting tolerance tests can be used. Currently available reference values for fasting tolerance tests have limitations in their use in daily practice. OBJECTIVE: The aim of this study was to determine the reference values of metabolites involved in glucose homeostasis dur
This study presents a new land cover map for the Upper Paraná River Basin (UPRB-2015), with high spatial resolution (30 m), and a high number of calibration and validation sites. To the new map, 50 Landsat-8 scenes were classified with the Support Vector Machine (SVM) algorithm and their level of agreement was assessed using overall accuracy and Kappa coefficient. The generated map was compared by
An ecological metaphor can enable transitions towards regenerative circular economies. Yet, this potential remains latent because its conceptual development, which is a prerequisite for its practical operationalization, is in its incipient phase and largely vague. To strengthen its epistemological underpinning, we propose a forward-looking interdisciplinary research agenda which brings together th
In this paper a new approach to a laser-produced plasma EUV source based on a tin target is presented. A thin layer of pure tin and composite layers consisting of Sn with Si, SiO and LiF are investigated. The target composed of several thin layers produces less debris than the other targets and provides a conversion efficiency (CE) in the 13.5-nm +/- 1% band at least comparable to the CE for the p
The aim of this study was to characterize the xylanolytic activity of Cryptococcus flavus isolate I-11. This microorganism was isolated from the Brazilian Cerrado, and enzyme plate assays showed that it also produces amylase and CMCase activity. The xylanolytic production of C. flavus isolate I-11 was improved by using a suitable combination of the carbon and nitrogen sources, reaching 130 U/mL A
80 procent av akademiker födda i Sverige har ett arbete som motsvarar deras kvalifikationer. I jämförelse så har endast 60 procent av invandrade akademiker ett kvalificerat arbete. Det är inte ovanligt att en del av dem blir tvungna att ta ett icke kvalificerat arbete för att kunna försörja sig. I den här uppsatsen diskuteras sex invandrade akademikers erfarenheter och upplevelser av hur det är a
2022 POLITICS, PUBLIC ART & PLACE BRANDING Welcome and listen to a lecture on politics and public art with Dr. Friederike Landau-Donnelly, where she is discusses questions such as 'Whose Walls, whose voices? Unpacking Vancouver's Politics of Public Art between Place Branding and Healing' The Pufendorf IAS Theme Public Art (2022), together with the CROCUS network and the Department of Service Manag
https://www.ses.lu.se/en/crocus/news-crocus/prior-events - 2026-07-21
Cancerstamceller orsak till återfall vid blodcancer – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Cancerstamceller orsak till återfall vid blodcancer 2010-10-29 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. På senare år har både exist
https://www.vetenskaphalsa.se/cancerstamceller-orsak-till-aterfall-vid-blodcancer/ - 2026-07-21
The tight junction protein claudin-4 has been reported to be overexpressed in advanced ovarian cancer. We investigated the prognostic significance of claudin-4 overexpression and whether claudin-4 expression could predict platinum response in primary ovarian carcinoma (OC). Claudin-4 expression was evaluated by immunohistochemistry in a tissue microarray of 140 OCs. Multivariable Cox-regression mo
The paper presents a study of key aspects in the design of a flexible unified data plane capable of integrating both fronthaul and backhaul transport in future 5G systems. In this study, we first review candidate access and multiplexing technologies from the state of the art and assess their capability to support legacy and new fronthaul and backhaul traffic. We then propose a new design framework
