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We have examined the effect of geometry optimisation on energies calculated with the quantum-mechanical (QM) cluster, the combined QM and molecular-mechanics (QM/MM), the big-QM approaches (very large single-point QM calculations taken from QM/MM-optimised structures, including all atoms within 4.5 Å of the minimal active site, all buried charged groups in the protein, and truncations moved at lea
In Sweden there are laws and recommendations from The National Board of Health and Welfare about the importance of a user's involvement in and possibility of influencing services directed at them. Even with such good intentions the same board reports that it is hard to know if people experience that they do. The purpose of my study was to examine how professionals can use their knowledge to he
I Sverige har särkullbarn en rätt att få ut sitt arv efter en förälder direkt efter förälderns bortgång. Samtidigt kan man i Sverige inte göra sina bröstarvingar arvlösa, utan ett barn har alltid rätt till sin laglott. Möjligheten att göra sina barn arvlösa ges inte heller genom testamenten eller gåvor. I Sverige har vi ett förstärkt laglottsskydd som fångar upp de fall olovliga överföringar av egIn Sweden, children from a previous relationship has a right to receive their inheritance from a parent directly after the parent's death. At the same time, is it not possible to make your children disinherited in Sweden. The opportunity to make your children disinherited is neither possible through gifts or will. In Sweden, we have a protection of the lawful share that captures illegal transf
Degrowth is an academic concept and activists' niche project in Europe and other early-industrialized parts of the world aiming to reframe the current sustainability challenge of declining environmental and unjust social conditions. Its emphasis is on the radical transformation of the current societal-economic structure in order to achieve inherently sustainable conditions. There are various d
The aim of this thesis was to expand the knowledge regarding the use and need of assistive devices, in particular mobility devices, and to investigate how, from a European perspective, the use of them changed during the ageing process. An additional aim was to explore the use of mobility devices in everyday life among very old Swedish women during a five-year period. Further, the aim was to contri
This thesis consists of an introduction and four self-contained chapters that address issues of how organizations and institutions should be designed in order to provide adequate incentives and enable coordination. The first essay uses a multi-task principal-agent model to examine two reasons why coordination problems are common when public sector organizations share responsibilities: the incenti
Debates of whether Z=114 and N=184 are the next magic numbers in nuclear physics have existed since the earliest predictions made in the 1960s. Until these days they have not been firmly established. To get a better understanding of the magic numbers, it is of key importance to study the nuclei in the vicinity of established and anticipated shell closures. Above shell closures, fast alpha-decaying
Introduction: Narasin is a feed additive for animals to treat the parasitic disease Coccidiosis. The antibiotic is deadly to humans when consumed in large amounts. Studies has shown that Narasin can transfer on Vancomycin resistant E. Faecium (VRE). Vancomycin is an antibiotic used to treat bacterial infections in humans. The resistance could be passed on to humans from the chicken and contribute
Observations of the ultra-sharp-lined HgMn star chi Lupi made with the Goddard High Resolution Spectrograph after the Hubble Space Telescope First Servicing Mission display the effect of COSTAR corrective optics upon the spectral resolution of several observing modes. The resolution is restored to levels expected in the absence of the telescope spherical aberration for all observations made throug
AIMS: Although the epidemiological association between Type 2 diabetes and congestive heart failure (CHF) as well as cardiovascular disease (CVD) is well established, associations between diabetes-related single-nucleotide polymorphisms (SNPs), CHF, and CVD have been surprisingly inconclusive. Our aim is to examine if 43 diabetes-related SNPs were associated with prevalent diastolic dysfunction as
Objective: The aims of this study are to validate infant vaccination data in the Swedish Vaccination Register (SVR) to the Swedish administrative coverage reports, and to assess differences in register-based vaccination coverage estimates between providers using different data reporting methods. Methods: The study population included all infants born in Sweden with a Swedish Personal Identity Numb
dc120111_pap 1..5 Performance of HbA1c as an Early Diagnostic Indicator of Type 1 Diabetes in Children and Youth KENDRA VEHIK, PHD 1 DAVID CUTHBERTSON, MS 1 DAVID BOULWARE, MS 1 CRAIG A. BEAM, PHD 1 HENRY RODRIGUEZ, MD 2 LAURENT LEGAULT, MD 3 MILA HYYTINEN, PHD 4 MARIAN J. REWERS, MD, PHD 5 DESMOND A. SCHATZ, MD 6 JEFFREY P. KRISCHER, PHD 1 THE TEDDY, TRIGR, DIABETES PREVENTION TRIAL-TYPE 1, AND T
https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/20%2006032016_679_20_Vehik_Diab%20Care_2012.pdf - 2026-07-04
Purpose: Dronedarone may increase digoxin plasma levels through inhibition of P-glycoprotein. Using real-world data, we evaluated the risk of digitalis intoxication in concomitant users of dronedarone and digoxin compared digoxin-alone users. Methods: We used the Clinformatics DataMart, a US claims database, to identify adult patients with atrial fibrillation (AF) or atrial flutter (AFL) who conco
OBJECTIVE: To investigate the association between long term residential exposure to road traffic and railway noise and risk of incident dementia.DESIGN: Nationwide prospective register based cohort study.SETTING: Denmark.PARTICIPANTS: 1 938 994 adults aged ≥60 years living in Denmark between 1 January 2004 and 31 December 2017.MAIN OUTCOME MEASURES: Incident cases of all cause dementia and dementi
Objective: To assess the mid-term outcomes and feasibility of branched endovascular repair (b-EVAR) of ruptured thoracoabdominal aortic aneurysms (rTAAAs). Methods: All patients undergoing b-EVAR of rTAAAs between 2011 and 2016 were included. Pre-, intra and postoperative imaging was reviewed to assess technical success, outcomes, and feasibility of b-EVAR in the emergent setting. Results: Eleven
BACKGROUND: Some per- and polyfluoroalkyl substances (PFAS) such as perfluorohexane sulfonic acid (PFHxS), perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) are very long-lived in humans, with serum half-lives of several years. In PFAS hot spots, such as Ronneby, Sweden, high exposures over time have led to markedly elevated serum PFAS levels, which may result in health risks
Molecular blood biomarkers are lacking for high-grade (HG) gastroenteropancreatic (GEP) neuroendocrine neoplasms (NEN). To histologically distinguish between neuroendocrine carcinoma (NEC), neuroendocrine tumors G3 (NET G3), adenocarcinoma and MINEN is often challenging. The mRNA-based NETest has diagnostic, prognostic and predictive value in neuroendocrine tumors G1-2 but has not been studied in
Postadress Box 117, 221 00 Lund Besöksadress Sandgatan 13, hus R Gamla Kirurgen Telefon, växel, 046-222 00 00 E-post jenny.egidius@sam.lu.se Webbadress www.sam.lu.se Lokalpro jek t Campus He ls ingborg 2030 Robert Holmberg, pro jek t ledare Verksamhetsbeskrivning för Campus Helsingborg vid Lunds universitet 1. Beskrivning av verksamheten Vid Campus Helsingborg bedriver Lunds universitet sedan 2000
La Repubblica - 07.11.2014 la Repubblica 31VENERDÌ 7 NOVEMBRE 2014CRONACA PER SAPERNE DI PIÙ www.giornataparkinson.it www.parkinson.it L’ IPOTESI di rimpiazzare i neuroni persi in una specifica malattia neurodege- nerativa, il morbo di Parkinson, con nuovi neuroni preparati in laboratorio, è da oggi più vicina. Su Cell Stem Cell, i colleghi dell’Università di Lund, in Svezia, guidati dalla giovane
