Sökresultat

Abstract is not available

Secretory lysosomes of natural killer (NK) cells combine storage, regulated secretion and lysosomal activity. We asked whether one could target exogenous proteins to the secretory lysosomes of NK-cells for final delivery into a tumor site upon degranulation. cDNAs for both soluble and transmembrane (tm) proteins were expressed in the human YT-Indy NK-cell line. Targeting of a soluble TNF receptor

Popular Abstract in Swedish Vi kan inte avslöja innehållet i våra tankar direkt, så hur kan vi närma oss de underliggande kognitiva processerna? Om vi vill lära oss mer om vad som försiggår i vår tankevärld, måste vi göra det indirekt, med hjälp av tankarnas yttre manifestationer. Det finns olika metoder som man kan ta till sin hjälp. I min avhandling kopplar jag ihop två ämnesområden, lingvistik In this thesis, I connect two disciplines, linguistics and vision research, and combine two methods, spoken language protocols and eye movement protocols, in order to cast light on the underlying cognitive processes. In a series of studies, I investigate the processual aspects of picture viewing and picture description. On the one hand, eye movements reflect human thought processes. It is easy to

We describe a test which uses the ability of viable cells to reduce 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) to detect resistance to a bactericidal drug, rifampin, in in vitro-cultured Mycobacterium tuberculosis. The assay shows a linear relationship between the number of viable bacteria and the ability to reduce MTT. Dead mycobacteria were unable to reduce MTT. Rifampin

In the absence of irradiation or other cytoreductive conditioning, endogenous hematopoietic stem cells (HSCs) are thought to fill the unique niches within the bone marrow that allow maintenance of full hematopoietic potential and thus prevent productive engraftment of transplanted donor HSCs. By transplantation of purified exogenous HSCs into unconditioned congenic histocompatible strains of mice,

The coagulation system is characterized by the sequential and highly localized activation of a series of serine proteases, culminating in the conversion of fibrinogen into fibrin, and formation of a fibrin clot. Here we show that C-terminal peptides of thrombin, a key enzyme in the coagulation cascade, constitute a novel class of host defense peptides, released upon proteolysis of thrombin in vitr

The purpose of Experimentation in Software Engineering: An Introduction is to introduce students, teachers, researchers, and practitioners to experimentation and experimental evaluation with a focus on software engineering. The objective is, in particular, to provide guidelines for performing experiments evaluating methods, techniques and tools in software engineering. The introduction is provided

Purpose: The purpose of the paper is to explore how knowledge contributes to value adding activities within real estate organisations. More specifically, the study aims to investigate; (1) how knowledge sharing activities are perceived in real estate organisations, (2) what motivates individuals to share knowledge and what incentives are used to support them, and (3) if employees in these organisa

We wanted to investigate if plasma levels of antimicrobial polypeptides (AMPs) are increased in severe sepsis and if they correlate with severity and mortality. Samples were collected from 31 sepsis patients at the intensive care unit. The Sequential Organ Failure Assessment (SOFA) score and 90-day mortality were registered, and inflammatory markers and AMP levels were measured by ELISA. A median