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Popular Abstract in Swedish Avhandlingens huvudsyfte är att försöka utreda hur man kommer till förståelse av det historiska huset och att diskutera vilken roll den historiska dokumentationen spelar i restaureringsprojekteringen. I restaurering som i allt annat arbete med arkitektur är förståelse ett nyckelord. Förståelse för de särskilda förutsättningar som ligger i uppgiften, i objektet, i skapanThe principal aim of the thesis is to evaluate the significance of the documentation of a building’s history for the work of restoring it and caring for it. Thus it may be said to address restoration as a hermeneutical problem, besides considering the relationships between the work of documentation; analyses of the resulting data; and the creative process in which the ideology of restoration is im

SCFA are important end products formed during colonic fermentation of dietary fibre (DF). It has been suggested that propionic and butyric acids affect metabolic parameters, low-grade systemic inflammation, insulin resistance and obesity. The aim of the present study was to investigate whether the various SCFA profiles observed after fermentation in the caecum of rats fed pectin, guar gum and fruc

Treatment of the electronically unsaturated cluster Os-3(CO)(8)(mu(3)-eta(2)-Ph2PCH2P(Ph)C6H4)(mu-H) (1) with benzothiophene in refluxing m-xylene afforded Os-3(CO)(7)(mu-PPh2)(mu-PMePh)(mu(3)-eta(2)-C6H4) (2), Os-3(CO)(7)(mu(3)-eta(2)-PPh(C6H4)CH2PPh)(mu(3)-eta(3)-SC8H5)(mu-H) (3), and Os-3(CO)(8)(mu-CO)(mu(3)-eta(2)-PPh(C6H4)CH2PPh) (4). Thermolysis of 1 in refluxing toluene for 35 h afforded on

Background: Chromosomal translocations t(11;22) (q24;q12) are characteristic of about 80-90% of Ewing's sarcoma family of tumors [bone and soft tissue Ewing's sarcoma and peripheral neuroectodermal tumors (PNET)]. They generate ews/fli1 rearrangements showing great diversity in breakpoint exon combination. In about 5% of Ewing's tumors, ews is fused to the erg gene at 21q22. The various chimeric p

Two hundred one consecutive, primary, noninfected Charnley (Thackray, Leeds) hip arthroplasties, implanted from 1968 to 1985 due to adult-onset rheumatoid arthritis, were matched in pairs with respect to year of operation, age, and sex with 201 Charnley prostheses implanted due to osteoarthritis. The 10-year survival estimate for nonrevisions was 95% in the rheumatoid group and 89% in the osteoart

Large clinical studies describing the typical clinical presentation of diabetic foot ulcers are limited and most studies were performed in single centres with the possibility of selection of specific subgroups. The aim of this study was to investigate the characteristics of diabetic patients with a foot ulcer in 14 European hospitals in ten countries. The study population included 1,229 consecutiv

objective Leptin and growth hormone-binding protein (GHBP) both show gender differences that might be explained by sex hormones. To study the potential relevance of oestradiol and testosterone, we have examined 80-year-old subjects in whom oestradiol is higher in men than in women. The interrelationships between leptin, insulin, GHBP and fat mass in this age group were also investigated. design a

PURPOSE: In order to increase the theoretical understanding of the concept of accessibility, this paper reports the results from an exploration of methodological difficulties inherent in systematic accessibility assessments of single persons' travel chains in urban public bus transport. In addition, Special Transport Service (STS) travellers' perception of environmental demands in public transport

Background Dietary fibre is thought to protect against colorectal cancer but this view has been challenged by recent prospective and intervention studies that showed no protective effect. Methods We prospectively examined the association between dietary fibre intake and incidence of colorectal cancer in 519 978 individuals aged 25-70 years taking part in the EPIC study, recruited from ten European

Human islet amyloid polypeptide (hIAPP), a pancreatic islet protein of 37 amino acids, is the main component of islet amyloid, seen at autopsy in patients with type 2 diabetes mellitus (DM2). To investigate the roles of hIAPP and islet amyloid in DM2, we generated transgenic mice expressing hIAPP in their islet beta cells. In this study, we found that after a long-term, high-fat diet challenge isl

A study to determine and compare the sensitivities and specificities of the comparative cervical tuberculin (CCT) and gamma-interferon (IFN-gamma) tests for the diagnosis of bovine tuberculosis was conducted on 30 zebu oxen. The results of the tests were compared with the presence of acid-fast bacilli found by bacteriological culturing and histopathological examinations. The sensitivity and specif

Popular Abstract in Swedish Målsättningen med avhandlingen är att analysera vilken roll småskaligt entreprenörskap som alternativ överlevnadsstrategi har spelat i Sierra Leone under den ekonomiska kris som drabbade landet efter självständighet på 1960-talet. Avhandlingen baseras på nätverksteori, snowball metod och det empiriska underlaget utgörs av en studie av utvecklingen i Sierra Leone, med avSierra Leone is a small country with rich mineral resources such as diamonds, bauxite, gold and iron ore. Other resources include fishing, forestry and fertile agricultural land, which enable people to farm without any sophisticated methods of mechanization. Nevertheless, with all its wealth in resources, the country is relatively poor and is one of the least developed countries in the Sub-Saharan

In this study we present a new aqueous two-phase system where both polymers are thermoseparating. In this system it is possible to recycle both polymers by temperature induced phase separation, which is an improvement of the aqueous two-phase system previously reported where one of the polymers was thermoseparating and the other polymer was dextran or a starch derivative. The polymers used in this

Pharmacological experiments were carried out on isolated basilar arteries (BA) from the brain vasculature of guinea-pig and rat in order to characterize post-junctional serotonergic receptors mediating contraction by the use of selective agonists and antagonists. The sensitivity to 5-HT was higher, but the intrinsic activity lower, in guinea-pig compared to rat vessels. The contractile potency of

Sixteen young patients with type 1 diabetes mellitus and rapidly progressive severe retinopathy were examined regarding serum levels of growth hormone before and after the i.v. administration of 200 micrograms thyrotropin-releasing hormone (TRH). Serum IGF I, HbA1c, blood pressure, urinary albumin, and serum creatinine levels were also measured. The control group consisted of type 1 diabetic patie

This dissertation focuses on the medieval nobility and its manors in the inland of Småland. The problems tackled in the dissertation may be divided into two major complexes. One concerns the emergence and growth of the Småland nobility in a long-term perspective, the second concerns the spatial conditions in which the nobles established their manors in the landscape. An important question concerns

Human embryonic skin fibroblasts were pretreated with transforming growth factor-beta (TGF-beta) for 6 h and then labeled with [35S]sulphate and [3H]leucine for 24 h. Radiolabeled proteoglycans from the culture medium and the cell layer were isolated and separated by isopycnic density-gradient centrifugation, followed by gel, ion-exchange and hydrophobic-interaction chromatography. The major prote

The plant- specific insert ( PSI) of cypro11 gene- encoding cyprosin, an aspartic proteinase from Cynara cardunculus, has been cloned by polymerase chain reaction ( PCR) into a bacterial expression vector. A rearranged form of this PSI in which the N- and C- terminal sequences were permutated to make it more similar to the structural arrangement observed in saposins was also cloned and expressed i