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BACKGROUND: Normal cell division is coordinated by a bipolar mitotic spindle, ensuring symmetrical segregation of chromosomes. Cancer cells, however, occasionally divide into three or more directions. Such multipolar mitoses have been proposed to generate genetic diversity and thereby contribute to clonal evolution. However, this notion has been little validated experimentally. PRINCIPAL FINDINGS:
Metabolic and psychiatric disturbances occur early on in the clinical manifestation of Huntington's disease (HD), a neurodegenerative disorder caused by an expanded CAG repeat in the huntingtin (HTT) gene. Hypothalamus has emerged as an important site of pathology and alterations in this area and its neuroendocrine circuits may play a role in causing early non-motor symptoms and signs in HD. Lepti
The Internet provides a space for new interpretations and conversations concerning religious practices to take place without the direct interference of religious authorities. The intention of this article is to highlight one vivid aspect of this development, Islamic themed hip-hop video clips distributed online. The visual aesthetics, the selection of pictures (or no pictures), themes and storylin
This aim of this article is to critically examine how the concept of culture is used in Sweden to explain the “failure” or the difficulties that Muslim immigrant families are experiencing with regards to their integration into the dominant society. Whereas, the Swedish society is often represented as ‘modern’, ‘progressive’, and ‘democratic’, immigrants with Muslim backgrounds are predominately de
Studies on the prevalence of symptoms in the general population and its' relation to LS in the oldest-old are to our knowledge non-existent. The aim of this study was to describe the frequency and experienced severity of elderly subjects' reported symptoms and how symptoms are related to LS. The study population consisted of 681 individuals aged 78-93 years, drawn from the longitudinal population
