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Ad4BP/SF-1 (Adrenal4 Binding Protein/Steroidogenic Factor-1 (NR5A1)) is a factor important for animal reproduction and endocrine regulation, and its expression is tightly regulated in the gonad, adrenal gland, ventromedial hypothalamic nucleus (VMH), and pituitary gonadotrope. Despite its functional significance in the pituitary, the mechanisms underlying pituitary-specific expression of the gene
A DNA variation in the coding region of the human cystatin C gene has been detected by direct sequencing. The polymorphism, a G/A transition, leads to an Ala/Thr variation in the penultimate amino acid of the signal peptide. The base substitution results in the loss of a SstII restriction site, thus allowing the design of a rapid polymerase chain reaction assay for analysis of this polymorphism in
Girls take up smoking at least as frequently as boys. Few studies have focused on gender differences in the impact of adolescent smoking. We evaluated the sex-specific effect of adolescent smoking on respiratory symptoms and lung function. All students in junior high and high schools in Nord-Trondelag County Norway, 1995-97, were invited to participate in a cross-sectional study. Information on sm
På senare år har den finansiella marknaden vuxit enormt mycket. I samband med värdepappershandel utsätts banker och andra finansiella aktörer för risker. För att få en kontroll på lönsamheten och inte utsättas för likviditetsproblem, har insikt om riskkontroller förbättrats. Value at Risk (VaR) är ett mycket erkänt och användbart mått vid riskmätningar. VaR definieras som ”den med viss sannolikhet
The trademark term has grown and evolved with time. Promoting phrases, i.e. slogans, are one type of mark that may be protected through trademark law. However, this process has not been simple. The inherent characteristics of slogans have caused great hesitation regarding their protection. Slogans consist of a number of words, sometimes full sentences, and often, include advertising messages. Can
This thesis seeks to examine the relationship between authenticity and co-creation in regards to tourism experiences. In order to explore the relationship between the two phenomena, the visitor/host interaction facilitated through CouchSurfing, an international online hospitality network, is used. This thesis focuses on the analyses of tourist experiences, drawing from narratives provided by inter
International roaming has been a frequently debated subject in the European telecom sector lately. While prices on most other mobile services have been reduced by half during the past few years, roaming charges have remained fairly static since the service was first introduced with the birth of GSM. While generating large profits for Europe’s dominating operators, the situation constitutes a restr
Introduction To achieve any possible positive effect on the intestinal mucosa cells it is important that probiotics adhere tightly onto the intestinal mucosa. It has been shown in healthy volunteers that Lactobacillus plantarum 299v (Lp 299v) (DSM 9843), a probiotic bacterium, given orally in a fermented oatmeal formula adheres onto the intestinal mucosa, but whether this also occurs in critically
Angle-resolved resonant Auger-electron spectroscopy has been carried out on the nitrogen molecule at selected photon energies around 419 eV, where a 1s core electron and two valence electrons are promoted into the lowest unoccupied molecular orbital 1pi(g). Significant enhancement of a specific band, which cannot be disentangled in direct photoionization, is observed at a binding energy of 37.6 eV
Ro 25-1553 is a metabolically stable analogue of endogenous vasoactive intestinal polypeptide (VIP). This compound is a potent bronchodilator in vitro as well as in vivo. Moreover, Ro 25-1553 has been shown to be highly selective of the VPAC2 receptor. We assessed the effect of Ro 25-1553 on isolated human bronchi and pulmonary arteries in vitro. Macroscopically normal human airways and pulmonary
Although there is a high degree of homology in the M2 transmembrane segments of alpha1 and beta1 subunits, subunit-specific effects were observed in alpha1beta1 GABA(A) receptors expressed in Spodoptera frugipedra (Sf9) cells when the conserved 13' threonine residue in the M2 transmembrane region was mutated to alanine. When threonine 263 (13') was mutated to alanine in the beta1 subunit, high-aff
Cytochrome (CYP) 4A11 and CYP4F2 are responsible for renal production of 20-hydroxyeicosatetraenoic acid, a vasoconstrictor and natriuretic substance. The CYP4A11 F434S and CYP4F2 V433M polymorphisms reduce 20-hydroxyeicosatetraenoic acid production in vitro. The aim of the present study was to evaluate the effect of these polymorphisms on blood pressure (BP) levels, hypertension prevalence, and r
Studies on the prevalence of symptoms in the general population and its' relation to LS in the oldest-old are to our knowledge non-existent. The aim of this study was to describe the frequency and experienced severity of elderly subjects' reported symptoms and how symptoms are related to LS. The study population consisted of 681 individuals aged 78-93 years, drawn from the longitudinal population
Purpose: To investigate the effect of Individual Placement and Support (IPS) according to diagnoses of schizophrenia, bipolar disorder, major depression, substance use disorders, or forensic psychiatric conditions. Methods: A systematic search of the literature was conducted in June 2017 and repeated in December 2020. The systematic review included 13 studies. Analyses of pooled original data were
Long time series of satellite remotely sensed Normalized Difference Vegetation Index (NDVI) as an indicator of vegetation greenness can be used in a broad range of research topics such as climate change, vegetation dynamics and desertification monitoring. The first phase of this study tests a practical method using Hyperion imagery onboard on Earth Observing-1 (EO1) spacecraft for simulation of MO
In 2001 the Doha Round Talks was initiated by the World Trade Organization. Development was the overarching goal. For several developing countries with a comparative advantage in agriculture, trade with such products is seen as essential to economic growth and thus development. In order to spur this development it appears to be particularly important that developing countries have increased access
