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The future of AIS conferences, thrown into sharp relief by virtual innovations during the pandemic and the subsequent return to face-to-face conferences, is debated in this special issue. This editorial introduces the seven papers contained in the special issue and provides the context for the debate on the future of conferences in the AIS Community as well as pinpointing key contributions made by
Background: Variation in residual volume between peritoneal dialysis dwells creates uncertainty in ultrafiltration determination, dialysis efficiency, and poses a risk of overfill if the residual volume is large. Measuring the dilution of a marker molecule during fluid fill offers a convenient approach, however, estimation accuracy depends on the choice of dilution marker. We here evaluate the fea
The emergence of autonomous learning has revolutionized educational systems, offering new pathways to enhance higher education. Across most Swedish universities, Bachelor's and Master's theses (final projects) represent an important part of students' academic journey. Embracing technology as a tool, rather than an end in itself, has become imperative in contemporary higher education and thesis pro
Microplastics (MP) have emerged as significant global pollutants, garnering considerable attention from both the scientific community and the public. The significance of microplastic research lies in its capacity to inform effective pollution control strategies and mitigate associated environmental and health risks. The review illuminated the complexities and challenges inherent in analyzing micro
Heavy metal (HM) pollution remains a pressing global concern, affecting soil regarding food safety, and negatively influencing the UN Sustainable Development Goals (SDGs). We investigated the efficacy of untreated cypress biochar (UCB) and Ca-modified cypress biochar (MCB) in mitigating HM contamination and enhancing growth across native and contaminated soils (40 mg/kg) in carrot pot experiments.
Groundwater is becoming increasingly important as surface water is decreasing and becoming more and more polluted. In particular, rural areas in the arid region of Central Asia face problems with both water quantity and quality. In view of this, we investigated the drinking water quality in the Maysky district in the Pavlodar region, Kazakhstan. The organoleptic properties, together with microbiol
Four directional and positional variants of sulfonamide-derivatized galactopyranosides were synthesized and evaluated against human galectin-1, -3, -4C (C-terminal), -7, -8N (N-terminal), -8C (C-terminal), -9N (N-terminal), and -9C (C-terminal), which revealed that one of the sulfonamide positions and directionalities (methyl 3-{4-[2-(phenylsulfonylamino)-phenyl]-triazolyl}-3-deoxy-α-D-galactopyra
The PARP-3 protein is closely related to the PARP-1 and PARP-2 proteins, which are involved in DNA repair and genome maintenance. Here, we characterized the biochemical properties of human PARP-3. PARP-3 is able to ADP-ribosylate itself as well as histone H1, a previously unknown substrate for PARP-3. PARP-3 is not activated upon binding to DNA and is a mono-ADP-ribosylase, in contrast to PARP-1 a
The 494 km long Latvian coast consists of sandy sediments, which serve as an excellent proxy for past coastal events and environment. Our study explores these understudied sediments along the western coast of the Gulf of Riga and combines two sand quartz-wise methods: optically stimulated luminescence (OSL) dating and grain microtextures. We provide a new chronology and microsedimentary results to
Glioblastoma (GBM) is the most aggressive form of glioma with a high rate of relapse despite intensive treatment. Tumor recurrence is tightly linked to radio-resistance, which in turn is associated with hypoxia. Here, we discovered a strong link between hypoxia and local complement signaling using publicly available bulk, single-cell, and spatially resolved transcriptomic data from patients with G
This paper aims to contribute to the field of policy enactment studies with a deepened understanding of the significance of the students when a pedagogical vision is enacted. The paper is based on a single case study using observations, surveys, interviews, and document studies. Informed by policy enactment theory, we analyse the students’ role in enacting the vision at the newly established Newsc
Att ställa om från fossila bränslen inom sjöfartssektorn kommer att bli ännu svårare än att vända en oljetanker. Det övergripande syftet med denna avhandling, som är förankrad i sustainability transitions-litteraturen, är att öka den nuvarande förståelsen för hur multiskalära uppifrån-och-ner- samt nerifrån-och-upp-processer påverkar sociotekniska förändringar som bidrar till minskade koldioxidutsShifting away from fossil fuels in the maritime shipping sector promises to be even more difficult than turning an oil tanker. Anchored in the sustainability transitions literature, the overall aim of this thesis is to advance the current understanding of how multi-scalar top-down and bottom-up processes influence socio-technical change towards decarbonisation of the global maritime shipping secto
Predictions of total dissolved solids (TDS) in water bodies including rivers and lakes are challenging but essential for the effective management of water resources in agricultural and drinking water sectors. This study developed a hybrid model combining Grey Wolf Optimization (GWO) and Kernel Extreme Learning Machine (KELM) called GWO-KELM to model TDS in water bodies. Time series data for TDS an
A comprehensive study of the local and nonlocal amplitudes contributing to the decay B0 → K*0(→ K+π−)μ+μ− is performed by analysing the phase-space distribution of the decay products. The analysis is based on pp collision data corresponding to an integrated luminosity of 8.4 fb−1 collected by the LHCb experiment. This measurement employs for the first time a model of both one-particle and two-part
Significant groundwater (GW) head decline due to excessive withdrawal is an essential hydrological concern in several major plains of Iran. The capacity of an aquifer to retain GW can be described through the storativity parameters. Traditional methods to define these parameters are costly, time-consuming, and sometimes ineffective. The storativity of an aquifer, irrespective of its confinement ty
Improper utilization of water resources has the potential to result in reduced availability of high-quality water and adverse effects on societal development. In fact, what appears to be a serious gap in comprehensive water resources studies is the lack of a coherent approach that can link different social, economic and environmental parts within the framework of the integrated water management pa
Pressure-induced polymorphism has recently been demonstrated in several high entropy alloys. This offers a new window into the much-debated issue of phase selection and stability in these systems. Here, we examine the effect of cryogenic temperatures on the pressure-induced transition from face centered cubic to hexagonal close-packed structures of the prototype CoCrFeMnNi (Cantor) alloy. We obser
