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Collaboration across disciplines and stakeholders is important in handling complex societal problems. Even if collaborating is acknowledged as contributing towards societal change and innovation, collaborators’ emotional experiences during development, consolidation and completion of a given project are underexplored. This article discusses emotional labour in three cross-sectoral collaborations u
The projected ocean acidification (OA) associated with increasing atmospheric CO2 alters seawater chemistry and hence the bio-toxicity of metal ions. However, it is still unclear how OA might affect the long-term resilience of globally important marine microalgae to anthropogenic metal stress. To explore the effect of increasing pCO2 on copper metabolism in the diatom Thalassiosira pseudonana (CCM
The rescript of 1688 granted the bishop and superintendent Theodorus Thorlacius (Latinised form of Þórður Þorláksson) permission to print Norwegian and Icelandic historical and antiquarian works, demonstrating the growing interest in Old Norse culture in the Scandinavian countries in the seventeenth century. The printing of Icelandic histories illustrates not only the growth and importance of prin
The anisotropic optical absorption edge of β-Ga2O3 follows a modified Beer-Lambert law having two effective absorption coefficients. The absorption coefficient of linearly polarized light reduces to the least absorbing direction beyond a critical penetration depth, which itself depends on polarization and wavelength. To understand this behavior, a Stokes vector analysis is performed to track the p
RNA medicines represent a paradigm shift in treatment and prevention of critical diseases of global significance, e.g., infectious diseases. The highly successful messenger RNA (mRNA) vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were developed at record speed during the coronavirus disease 2019 pandemic. A consequence of this is exceptionally shortened vaccine deve
Quality requirements are critical for successful software engineering, with maintainability being a key internal quality. Despite significant attention in software metrics research, maintainability has attracted surprisingly little focus in the Requirements Engineering (RE) community. This position paper proposes a synergistic approach, combining code-oriented research with RE expertise, to create
The future of AIS conferences, thrown into sharp relief by virtual innovations during the pandemic and the subsequent return to face-to-face conferences, is debated in this special issue. This editorial introduces the seven papers contained in the special issue and provides the context for the debate on the future of conferences in the AIS Community as well as pinpointing key contributions made by
Background: Variation in residual volume between peritoneal dialysis dwells creates uncertainty in ultrafiltration determination, dialysis efficiency, and poses a risk of overfill if the residual volume is large. Measuring the dilution of a marker molecule during fluid fill offers a convenient approach, however, estimation accuracy depends on the choice of dilution marker. We here evaluate the fea
The emergence of autonomous learning has revolutionized educational systems, offering new pathways to enhance higher education. Across most Swedish universities, Bachelor's and Master's theses (final projects) represent an important part of students' academic journey. Embracing technology as a tool, rather than an end in itself, has become imperative in contemporary higher education and thesis pro
Four directional and positional variants of sulfonamide-derivatized galactopyranosides were synthesized and evaluated against human galectin-1, -3, -4C (C-terminal), -7, -8N (N-terminal), -8C (C-terminal), -9N (N-terminal), and -9C (C-terminal), which revealed that one of the sulfonamide positions and directionalities (methyl 3-{4-[2-(phenylsulfonylamino)-phenyl]-triazolyl}-3-deoxy-α-D-galactopyra
The PARP-3 protein is closely related to the PARP-1 and PARP-2 proteins, which are involved in DNA repair and genome maintenance. Here, we characterized the biochemical properties of human PARP-3. PARP-3 is able to ADP-ribosylate itself as well as histone H1, a previously unknown substrate for PARP-3. PARP-3 is not activated upon binding to DNA and is a mono-ADP-ribosylase, in contrast to PARP-1 a
The 494 km long Latvian coast consists of sandy sediments, which serve as an excellent proxy for past coastal events and environment. Our study explores these understudied sediments along the western coast of the Gulf of Riga and combines two sand quartz-wise methods: optically stimulated luminescence (OSL) dating and grain microtextures. We provide a new chronology and microsedimentary results to
Glioblastoma (GBM) is the most aggressive form of glioma with a high rate of relapse despite intensive treatment. Tumor recurrence is tightly linked to radio-resistance, which in turn is associated with hypoxia. Here, we discovered a strong link between hypoxia and local complement signaling using publicly available bulk, single-cell, and spatially resolved transcriptomic data from patients with G
This paper aims to contribute to the field of policy enactment studies with a deepened understanding of the significance of the students when a pedagogical vision is enacted. The paper is based on a single case study using observations, surveys, interviews, and document studies. Informed by policy enactment theory, we analyse the students’ role in enacting the vision at the newly established Newsc
Att ställa om från fossila bränslen inom sjöfartssektorn kommer att bli ännu svårare än att vända en oljetanker. Det övergripande syftet med denna avhandling, som är förankrad i sustainability transitions-litteraturen, är att öka den nuvarande förståelsen för hur multiskalära uppifrån-och-ner- samt nerifrån-och-upp-processer påverkar sociotekniska förändringar som bidrar till minskade koldioxidutsShifting away from fossil fuels in the maritime shipping sector promises to be even more difficult than turning an oil tanker. Anchored in the sustainability transitions literature, the overall aim of this thesis is to advance the current understanding of how multi-scalar top-down and bottom-up processes influence socio-technical change towards decarbonisation of the global maritime shipping secto
