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Genetic variation in the cluster on chromosome 15, encoding the nicotinic acetylcholine receptor subunits (CHRNA5-CHRNA3-CHRNB4), has shown strong associations with tobacco consumption and an additional risk increase in smoking-related diseases such as chronic obstructive pulmonary disease (COPD), peripheral artery disease and lung cancer.
A high-performance and flexible analog-to-digital converter (ADC), that can be integrated in deep-submicron CMOS technology, is a key building block for reduced size, cost and power consumption of digital communication systems. This dissertation concerns the investigation of particular problems associated with the design of such ADCs. The problem of increased clock jitter sensitivity of low-pass
This article aims to contribute to the understanding concerning the introduction of crisis psychotherapy in the 1970s in psychiatric clinics in Sweden. The article discusses how this psychotherapy became central in the work of the clinics in supporting patients to well-being and inner growth. The ambition was that patients in an acute crisis-situation would be offered care immediately, aiming at a
BACKGROUND: Amplification of the oncogene MYCN in double minutes (DMs) is a common finding in neuroblastoma (NB). Because DMs lack centromeric sequences it has been unclear how NB cells retain and amplify extrachromosomal MYCN copies during tumour development. PRINCIPAL FINDINGS: We show that MYCN-carrying DMs in NB cells translocate from the nuclear interior to the periphery of the condensing chr
During 1972–1975, the breeding waterfowl populations of the northern parts of Fennoscandia (south to 65° N in Sweden) were surveyed for the first time. In 2009, a new survey was undertaken in the Swedish part of the mountain chain. Censuses were performed from the air in transects of 5×5 km squares and in special areas. The distribution of the different species was largely similar between the two
Abstract Aim: To investigate trends in mortality and morbidity in very preterm infants. Methods: Population-based perinatal register; liveborn infants 22 + 0 to 31 + 6 gestational weeks were investigated (time period 1995-2004). Time trends for mortality and common morbidities were explored using logistic regression analyses. Results: Data from 1614 liveborn infants were included. There was an inc
Data concerning the persistent reduction of flow velocities measured by transcranial color-coded sonography (TCCS) in relation to the clinical and radiological outcome among patients with ischemic events in middle cerebral artery (MCA) territory is scarce. Patients with > or = 50% reduction of peak systolic velocities (PSV-MCA) as compared to the contralateral MCA were prospectively included in fo
This article studies continued childbearing and union stability among "power couples," or dual-career couples. The determinants of these events are analysed multivariately using longitudinal data on couples from population registers in Sweden, 1991–2005. Power couples are identified using their levels and fields of education, and their sectors of employment. Income and other variables are controll
Abstract is not available
An in-house written software package was used to generate templates of QRS complexes and T waves using self-similarity techniques, and leave a residual signal representing only atrial activity. The templating performance differences between individual ECG leads were tested. The mean number of templates in each of the 3 ECG leads was 8±4, 2±1, 7±5 for the QRS complexes, and 11±5, 11±8, 10±5 for the
In this chapter a technology for the enhancement of video data obtained at low light levels is presented. The method was inspired by the way in which nocturnal animals adaptively sum intensities, spatially and temporally, to improve vision at night. Due to the low photon count under these conditions the visual input is dark and unreliable, which leads to noisy low contrast images. The noise become
Popular Abstract in Swedish Hjärtkärlsjukdomar brukar definieras som ateriosklerotiska och tromboemboliska förändringar i hjärta, hjärna och i den arteriella blodcirkulationen. Dessa sjukdomar är mycket vanliga, och i Sverige insjuknar ca 40 000 personer i hjärtinfarkt och c 35 000 i hjärnblödning per år. Trots att det skett en sänkning av både incidens och dödlighet för dessa sjukdomar i västvärlThe Cardiovascular Risk Factor Study in Southern Sweden, CRISS, was initiated to explore if men at increased risk at developing CVD risk factors can be identified already before age 40. Starting in 1990 two birth cohorts of men residing in Helsingborg, Sweden, were surveyed at age 37 (n=991, participation rate 68%), at age 40 (n=770) and age 43 (n=702), respectively. A study questionnaire, a physi
We study the interplay between money market development and changes in monetary policy operating procedures in 11 European countries from c. 1980 up to the launch of EMU. Aspects of money market development such as the size and structure of different market segments, and institutional and regulatory changes, are addressed. We recount and empirically examine the extent of reorientation of monetary
