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As well as contributing to society, corporate social responsibility (CSR) initiatives have frequently been utilized by businesses to gain a competitive edge. Nevertheless, despite companies’ endeavors to leverage their CSR initiatives, limited stakeholder awareness of these efforts poses challenges to fully realize the strategic value of CSR. Hence, the primary objective of this study was to exami
By introducing the concept of high-reach AI, this paper focuses on AI systems whose widespread use may generate significant risks for both individuals and societies. While some of those risks have been recognised under the AI Act, we are analysing the rules laid down by the Digital Services Act (DSA) for recommender systems used by dominant social media platforms, as a prominent example of high-re
Relatively little is known about the relationship between socio-demographic factors and the chemical exposome in adolescent populations. This knowledge gap hampers global efforts to meet certain UN sustainability goals. The present work addresses this problem in Swedish adolescents by discerning patterns within the chemical exposome and identify demographic groups susceptible to heightened exposur
In “Selling luxury” perfume and cosmetics stores are approached as mediated physical experiences of luxury. The elusive character of smell has forced perfume brands to invoke guides to explain how their products should be experienced. These guides may be human, in the form of sales assistants, or non-human, in the form of visual marketing materials, packaging and store displays. In the context of
We present a method that allows enabling matrix element corrections (MECs) in Pythia8 with MC@NLO matching, without incurring double counting. MECs are an interesting feature that may contribute to the accuracy of theoretical predictions, alongside matching and merging. We directly compare our method to a specific choice of settings in Pythia8, which can remove double-counting for MECs in certain
Tetrodotoxin (TTX) is a marine toxin responsible for many intoxications around the world. Its presence in some pufferfish species and, as recently reported, in shellfish, poses a serious health concern. Although TTX is not routinely monitored, there is a need for fast, sensitive, reliable, and simple methods for its detection and quantification. In this work, we describe the use of an automated pa
Objective: Emerging research suggests that rheumatoid arthritis (RA) is associated with intestinal dysbiosis. This prospective pilot study evaluates changes in intestinal microbial composition in patients with RA initiating treatment with either methotrexate (MTX) or a tumor necrosis factor inhibitor (TNFi). Methods: Consecutive patients, fulfilling the 2010 American College of Rheumatology/EULAR
Inference and simulation in the context of high-dimensional dynamical systems remain computationally challenging problems. Some form of dimensionality reduction is required to make the problem tractable in general. In this paper, we propose a novel approximate Gaussian filtering and smoothing method which propagates low-rank approximations of the covariance matrices. This is accomplished by projec
Environmental degradation is one of the most significant challenges faced by humanity, yet current global politics struggle to implement collective solutions. Previous research has suggested that the EU has a leadership role in the international climate change regime complex, which refer to a set of overlapping institutions that address different aspects of climate governance. Moreover, within the
Overall health relies on features of skeletal muscle that generally decline with age, partly due to mechanisms associated with mitochondrial redox imbalance and bioenergetic dysfunction. Previously, aged mice genetically devoid of the mitochondrial NAD(P)+ transhydrogenase (NNT, encoded by the nicotinamide nucleotide transhydrogenase gene), an enzyme involved in mitochondrial NADPH supply, were sh
Ethics and politics in a new materialist framework are key issues in current debates and spark research in a wide array of fields from matters of sex and gender to ecology and art theory. However, a definition of politics, and how it relates to democracy, is often left out of these discussions. This article addresses that issue through the theory of radical democracy and politics as rupture from J
The mythology of the European Union (EU) in world politics can be told and untold in many different ways. This article focuses on the lore or stories of who did what to whom, the ideological projection of the past onto the present and the escapist pleasure of storytelling in looking at the mythology of ‘global Europa’– the EU in the world. It concludes with a reflection on the way in which the man
LINE-1 (L1) retrotransposons are a noted source of genetic diversity and disease in mammals. To expand its genomic footprint, L1 must mobilize in cells that will contribute their genetic material to subsequent generations. Heritable L1 insertions may therefore arise in germ cells and in pluripotent embryonic cells, prior to germline specification, yet the frequency and predominant developmental ti
The mouse genome is replete with retrotransposon sequences, from evolutionarily young elements with mutagenic potential that must be controlled, to inactive molecular fossils whose sequences can be domesticated over evolutionary time to benefit the host genome. In an exciting new study, de la Rica and colleagues have uncovered a complex relationship between ten-eleven translocation (TET) proteins
The reversal of the hydrolytic activity of α-mannosidase from jack bean has been studied in high concentrations of mannose. From an initial concentration of 85% mannose (w/w), a maximum yield of 70% (w/w) di- and oligosaccharides was obtained. The products were separated by gel chromatography and high-performance liquid chromatography, and characterized by gas-liquid chromatographymass spectrometr
The procedural and institutional rights granted by the EU Charter of Fundamental Rights have an important impact at national level in the application and interpretation of competition law by national courts and national authorities. In Sweden, the situation is particularly fascinating since the principle of openness – which affords a maximum standard of human right protection – may conflict with t
