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Type 2 diabetes (T2D) is a global public health challenge. Whilst the advent of genome-wide association studies has identified >400 genetic variants associated with T2D, our understanding of its biological mechanisms and translational insights is still limited. The EPIC-InterAct project, centred in 8 countries in the European Prospective Investigations into Cancer and Nutrition study, is one of th
Why do large differences in fiscal capacity exist between states in the Global South? We constructa comprehensive new dataset of tax and revenue collection for 46 African polities from 1900 to2015. Descriptive analyses show that many polities in Africa have been characterized by stronggrowth in real tax collection. As a next step, we employ these data to test theories of fiscal capac-ity in a lon
The small intestine is a specialised organ, essential for nutrient digestion and absorption. It is lined with a complex epithelial cell layer. Intestinal epithelial cells can be cultured in three-dimensional (3D) scaffolds as self-organising entities with distinct domains containing stem cells and differentiated cells. Recent developments in bioengineering provide new possibilities for directing t
Previous studies on sustainability support the idea that the introduction of specific projects and certifications on sustainability increase the quality of wine production while specific requirements enhance environmental biodiversity and efficiency considering several aspects, such as water consumption and fertilizer use. These studies are mainly based on case studies and focus in part
Better understanding and reducing gender gaps in the labor market remains an important policy goal. We study the role of advice in sustaining these gender gaps using a laboratory experiment. In the experiment, “advisers” advise “workers” to choose between a more ambitious and a less ambitious task based on the worker’s subjective self-assessment. We expected female workers to be less confident and
There is no doubt that COVID-19 will have a substantial impact on access to biologics and biosimilar uptake, as well as on the related ethical, legal, and social dimensions of prioritization decisions. This holds especially true for Denmark and European markets, where governments are expected to cover most of the pharmaceutical needs of their citizens and where the crisis has been leading to an im
This chapter presents the theory of ecologically unequal exchange (EUE). The theory explains asymmetric transfers of non-monetary, biophysical resources and environmental harms between different countries or regions. The chapter provides a cursory review of the literature on methods for empirically identifying such asymmetries and testing hypotheses derived from the theory. To identify EUE require
We describe recent developments of the public computer code HiggsBounds. In particular, these include the incorporation of LHC Higgs search results from Run 2 at a center-of-mass energy of 13 TeV, and an updated and extended framework for the theoretical input that accounts for improved Higgs cross section and branching ratio predictions and new search channels. We furthermore discuss an improved
A microcalorimetric vessel for monitoring the initial phases of cytotoxic reactions in the micro-submicrowatt region has been designed and tested. The vessel is intended to be used witha multichannel microcalorimetric system from Thermometric, Järfälla, Sweden and can be built up stepwise in a modular way. The different functions of perfusion, stirring and addition of small amounts of soluble immu
Abstract in UndeterminedSmall-scale distributed generators connected tothe low voltage network are generally operated with unitypower factor. However, controlling their reactive powerinjection would have an impact on the voltage at theirconnection point, if the network is sufficiently weak andinductive. The purpose of this paper is to investigate how asmall-scale distributed generator connected to
A decomposition of the field of the wave equation in three dimensions is suggested. This wave splitting decomposes the field into two components such that in free space simple propagation properties are obtained. The inhomogeneous region is assumed to have a phase velocity variation that varies only in the radial coordinate r from the origin. The suggested wave splitting is a generalization of the
In traditional diffusion MRI, short pulsed field gradients (PFG) are used for the diffusion encoding. The standard Stejskal-Tanner sequence uses one single pair of such gradients, known as single-PFG (sPFG). In this work we describe how trajectories in q-space can be used for diffusion encoding. We discuss how such encoding enables the extension of the well-known scalar b-value to a tensor-valued
