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Blood coagulation has a Janus-faced role in infectious diseases. When systemically activated, it can cause serious complications associated with high morbidity and mortality. However, coagulation is also part of the innate immune system and its local activation has been found to play an important role in the early host response to infection. Though the latter aspect has been less investigated, phy
Investigation of optimized spatial precision for surface temperature measurements is performed. The temperature is measured by means of two-color ratio imaging with ICCD cameras, using the thermographic phosphor BAM. The precision in temperature is put in relation to the spatial resolution, two quantities which involve a trade-off in this case: the more spatial smoothing the better precision, but
Huntington's disease is an inherited neurodegenerative disorder characterised by motor, cognitive and psychiatric disturbances. Patients exhibit other symptoms including sleep and mood disturbances, muscle atrophy and weight loss which may be linked to hypothalamic pathology and dysfunction of hypothalamo-pituitary axes.
The iterative quasiparticle random-phase approximation (QRPA) method we previously developed [Phys. Rev. C 81, 034312 (2010); 86, 024303 (2012); 86, 014307 (2012)] to accurately calculate properties of individual nuclear states is extended so that it can be applied for nuclei with odd numbers of neutrons and protons. The approach is based on the proton-neutron QRPA (pnQRPA) and uses an iterative n
We performed transient absorption (TA) measurements on CP29 minor light-harvesting complexes that were reconstituted in vitro with either violaxanthin (Vio) or zeaxanthin (Zea) and demonstrate that the Zea-bound CP29 complexes exhibit charge-transfer (CT) quenching that has been correlated with the energy-dependent quenching (qE) in higher plants. Simulations of the difference TA kinetics reveal t
Smooth muscle cells in the urinary bladder are involved in the control of urine filling and emptying. We have used mice to study the contractile regulation of urinary bladder smooth muscle during the fetal period. We found that nerve-induced contractions are mainly dependent on muscarinic receptor activation in the newborn whereas adult bladders are equally dependent on muscarinic and purinergic r
High-spin states have been studied in Pr-135(59), populated through the Cd-116(Na-23,4n) reaction at 115 MeV, using the Gammasphere gamma-ray spectrometer. The negative-parity yrast band has been significantly extended to spin similar to 45 (h) over bar and excitation energy 21.5 MeV, showing evidence for several rotational alignments. The positive-parity yrast band of Ce-135(58), populated throug
Microbial forensics is an important part of a strengthened capability to respond to biocrime and bioterrorism incidents to aid in the complex task of distinguishing between natural outbreaks and deliberate acts. The goal of a microbial forensic investigation is to identify and criminally prosecute those responsible for a biological attack, and it involves a detailed analysis of the weapon-that is,
The article relates the concept of God's "plan" in Job 38:2 and 42:3 to similar concepts in earlier Ancient Near Eastern mythological literature, especially the term niklātu ("wise, ingenious things") used in the Babylonian Enuma Elish to describe the actions of Marduk - both the battle against the chaos monster Tiamat and the creation of the earthly world. Parallels are also drawn to expressions
The honeycomb lattice material Li2RuO3 undergoes a dimerization of Ru4+ cations on cooling below 270 degrees C, where the magnetic susceptibility vanishes. We use density functional theory calculations to show that this reflects the formation of a valence bond crystal, with a strong structural bond disproportionation. On warming, x-ray diffraction shows that discrete threefold symmetry is regained
Coeliac disease (CD) is becoming a model for understanding the pathogenesis of autoimmune disorders. In CD, antibodies against transglutaminase 2 (TG2) and specific glutamine residues of gliadins have been identified. A similar situation is seen in rheumatoid arthritis with both anticitrullinated protein antibodies (ACPA) and auto-antibodies against the citrullinating enzyme, peptidylarginine deim
The collection examines the view of the holiness in the "Holy Land" through the writings of pilgrims, travelers, and missionaries. The period extends from 1517, the Ottoman conquest of Syria and Palestine, to the Franco-British treaty of Utrecht in 1713 and the consolidation of European hegemony over the Mediterranean. The writers in the collection include Christians (Orthodox, Protestant, and Cat
One of the major symptoms of the neurodegenerative condition Parkinson's disease (PD) is a slowness or loss of voluntary movement, yet frustratingly therapeutic strategies designed to restore movement can result in the development of excessive abnormal movements known as dyskinesia. These dyskinesias commonly develop as a result of pharmacotherapy in the form of L-DOPA administration, but have als
This paper investigates the distribution of embedded verb second in Faroese, Icelandic, Norwegian, and Swedish. Two conclusions can be drawn from the study. First, none of the Scandinavian languages can be said to display generalized embedded verb second across the board. There are varieties of Faroese and Icelandic that display restrictions of the kind found in the other Scandinavian languages. I
Let mu be a finite positive measure on the closed disk (D) over bar in the complex plane, let 1 <= t < infinity, and let P-t(mu) denote the closure of the analytic polynomials in L-t(mu). We suppose that D is the set of analytic bounded point evaluations for P-t(mu), and that P-t(mu) contains no nontrivial characteristic functions. It is then known that the restriction of mu to partial derivative
Pseudocoordination is a construction where two verbs or VPs appear to be conjoined by what looks like the conjunction och ‘and’. In my paper I focus on pseudocoordination with gå ‘walk, go’ as Verb 1, in particular cases where this has been claimed to give rise to a “surprise effect” (Wiklund 2005, 2008). I set out from the assumption that Verb 1 in pseudocoordination is a light verb, which, follo
Background: Resource allocation in public health care principally involves politicians, administrators, and physicians. They all have their different roles, agendas and ambitions when it comes to how public health care resources should be spent. Previous studies on attitudes among health-care stakeholders have mainly focused on views and preferences among clinical decision-makers, while less atten
Sperm performance is likely to be an important determinant of male reproductive success, especially when females copulate with multiple males. Understanding sperm performance is therefore crucial to fully understand the evolution of male reproductive strategies. In this study, we examined the repeatability of sperm morphology and motility measures over three breeding seasons, and we studied relati
Compared with the effect of invaders on the native terrestrial fauna of New Zealand, interactions between native fishes and introduced trout (sports fish in the genera Salmo, Oncorhynchus and Salvelinus) are less well known and there have been fewer efforts to remedy their effects. Trout have caused widespread reductions in the distribution and abundance of native galaxiid fishes, a family dominat
