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Writing as dusk fell on the mid-Republic, Ennius (238–169 BCE) purportedly remarked, ‘Kings throughout their kingship are in quest of statues and sepulchres; they build up a name and strain with all their might and main’. A poet whose verse mediated between the Greek and Roman worlds, he knew the weight of his words, and they usefully highlight the political presence of a tomb. Not that this is un
This Letter presents the first direct investigation of the p–Σ0 interaction, using the femtoscopy technique in high-multiplicity pp collisions at s=13 TeV measured by the ALICE detector. The Σ0 is reconstructed via the decay channel to Λγ, and the subsequent decay of Λ to pπ−. The photon is detected via the conversion in material to e+e− pairs exploiting the capability of the ALICE detector to mea
The aim of the article is to present a model of causal relations that is based on what is known about human causal reasoning and that forms guidelines for implementations in robots. I argue for two theses concerning human cognition. The first is that human causal cognition, in contrast to that of other animals, is based on the understanding of the forces that are involved. The second thesis is tha
The cooperative interplay between the functional devices of a preorganized active site is fundamental to enzyme catalysis. An in-depth understanding of this phenomenon is central to elucidating the remarkable efficiency of natural enzymes and provides an essential benchmark for enzyme design and engineering. Here, we study the functional interconnectedness of the catalytic nucleophile (His18) in a
The enzymes that facilitate phosphate and sulfate hydrolysis are among the most proficient natural catalysts known to date. Interestingly, a large number of these enzymes are promiscuous catalysts that exhibit both phosphatase and sulfatase activities in the same active site and, on top of that, have also been demonstrated to efficiently catalyze the hydrolysis of other additional substrates with
Potato epoxide hydrolase 1 exhibits rich enantio- and regioselectivity in the hydrolysis of a broad range of substrates. The enzyme can be engineered to increase the yield of optically pure products as a result of changes in both enantio- and regioselectivity. It is thus highly attractive in biocatalysis, particularly for the generation of enantiopure fine chemicals and pharmaceuticals. The presen
Evolutionary biologists today debate whether it is convenient to revise the standard theory of evolution, or if an Extended Evolutionary Synthesis is necessary. However, the conceptual relationship between the standard theory of evolution (also known as the Modern Synthesis) and a putative Extended Evolutionary Synthesis is not clear. One concept in philosophy of science that has traditionally bee
The book is a comparative study in the status of international human rights norms in the domestic law of all the Nordic countries and the three Baltic states: Estonia, Latvia and Lithuania. An amazingly rapid development towards direct applicability of international human rights treaties has taken place in recent years in all the countries in question. This book provides in-depth analysis of the s
High-order harmonic generation (HHG) in gases is inherently inefficient, prompting ongoing efforts to enhance the output of coherent table-top XUV sources. In this study, we investigate the influence of the laser pulse duration on HHG using a compact post-compression method featuring a bulk multi-pass cell. This setup enables tunable Fourier-limited pulse durations as short as 42 fs. We examine th
Creatinine is a widely used clinical biomarker in adult and pediatric patients to estimate kidney function and glomerular filtration rate. There are however few recent studies that have addressed method performance in the creatinine range relevant for children. This study aimed to describe measurement performance in the pediatric concentration range by comparing commonly used enzymatic methods on
This work presents a statistical approach for estimating and analyzing the downward transport pattern and distribution of soil water by the use of pattern analysis of space-time correlation structures. This approach, called the Space-time Correlation Field, is mainly based on the analyses of correlation functions simultaneously in the space and time domain.The overall purpose of this work is to de
This editorial introduces the Special Section on 'The Borders Within: Socio-Economic Rights and Non-discrimination in EU Law' whose purpose is to provide a comprehensive and non-fragmented understanding of socio-economic rights, the right to non-discrimination and their meaning for welfare in EU Member States. Under EU law the boundaries between national socio-economic policies and the enjoyment o
Health is multifaceted, with divergent interpretations in diverse cultures and groups of individuals. The ways individuals understand health might aid in developing future interventions. There is scant knowledge on how adolescents with depression conceptualise health. A descriptive qualitative design with a phenomenographic approach was used to describe the different ways adolescents with depressi
In this paper we explore cyber security practices in Swedish manufacturing firms. Manufacturing is being trans- formed by new technologies under the label of smart industry or industry 4.0. Most of these technologies are either digital themselves or depend on digital connectivity. Their use is made possible by electronic sensors, actuators, and other devices as well as by data-driven analysis. Thi
This article is based on the creation of sports heritage as having strong roots in the Anthropocene. It particularly discusses listed building declarations of the built heritage of sport, from a Swedish perspective, as well as the feelings of nostalgia associated with such activities. Two contemporary examples of preserved sports heritage sites, Hindås Ski Jumping Hill in Hindås and the stand at V
