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Popular Abstract in Swedish Nätverk av nervtrådar påvisades kring koronara artärer och vener från marsvin och människa. Medelst immunhistokemiska metoder demonstrerades olika signalsubstanser i anknytning till dessa nervtrådar och i olika delar av kärlväggen (endotelet, media, adventitia), och det påvisades hur vissa av dessa substanser var lokaliserade i samma vesikler av ovan nämnda nervtrådar. A network of perivascular nerve fibres was demonstrated in coronary arteries and veins from guinea-pig and man. Nerve fibres displaying immunoreactivity to neuropeptide Y (NPY) had a distribution pattern similar to those containing immunoreactivity to tyrosine hydroxylase. Immunoreactivity to substance P and calcitonin gene-related peptide (CGRP) occurred in the same varicose nerve fibres, which w

OBJECTIVE: 5-azacytidine (azacytidine), a DNA hypomethylating agent, was recently approved as the first therapeutic agent for the treatment of myelodysplastic syndromes. The present subcutaneous dosing schedule, 75 mg/m(2) for 7/28 days, is based on early clinical studies and may constitute a practical problem for patients. The present in vitro study aimed at evaluating the pharmacodynamics of aza

The phylogeny of the Patagonian-Antarctic genus Himantormia is investigated with nuclear ITS rDNA sequences in PAUP. The monotypic genus Nimisia is synonymized with Himantormia, and the new combination H. deusta is proposed. The secondary chemistry was investigated using HPLC; protocetraric, stictic, succinprotocetraric and confumarprotocetraric acids were detected in H. deusta for the first time,

We present a polynomial time method for identifying the maximal set in excess demand at a given payoff vector. This set can be used in "large" partnership formation problems to identify the minimum element in the set of individually rational payoff vectors at which there is no overdemanded set of agents. This minimum element corresponds to the minimum Walrasian equilibrium price vector in a specia

Student–industry activities are often heralded as win–win–win activities in which students gain knowledge of their future professional fields, companies access student knowledge, and universities both offer students stimulating learning opportunities and strengthen ties with industry. Student–industry projects can be defined as an active learning methodology characterized by pedagogical values suc

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A negative attitude to a construction project by stakeholders can severely obstruct its implementation. Such obstruction will cause cost overruns and exceeded time schedules due to conflicts and controversies concerning project design and implementation. A case study consisting of two projects has been undertaken to investigate how the problems of managing the concerns of stakeholders present them

The management of construction tolerances is a necessary and routine part of the construction activity and is normally brought to our attention only when failures are reported. In a study of tolerance management, the authors found widespread evidence of the same failures and the reasons for them. There seems to be no shortage of experience of the effects of failures in tolerances or of knowledge a

As scientific knowledge grows, it often engenders controversy. The aim of the particular case of controversy studied here, in a series of letters exchanged between two phoneticians, is to capture vacillations of a discipline (phonetics) and its “actants” (phoneticians and their equipment), described at a key moment in the history of the discipline (an historical “turning point”), i.e. when phoneti

In recent decades, the development of technology that aids in documenting, analysing and communicating information regarding archaeological sites has affected the way that historical information is transmitted and perceived by the community. Digital technologies have affected archaeology at all levels; for example, novel investigation methods have highlighted new and unknown aspects of archaeologi