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PURPOSE: To determine the effect of radiotherapy in doses 14 to 20 Gy on eradication of carcinoma-in-situ (CIS) testis and on the Leydig cell function. PATIENTS AND METHODS: Forty-eight patients presented with unilateral testicular germ cell cancer and CIS of the contralateral testis. The CIS-bearing testis was treated with daily irradiation doses of 2 Gy, 5 days a week, to a cumulative dose of 20
The aim of this study was to assess whether the TP53 Arg72Pro polymorphism is associated with an increased risk of non-small cell lung cancer (NSCLC). Additionally, in NSCLC patients, we investigated a potential association between this polymorphism and somatic TP53 gene mutations in tumour cells. The study group included 240 NSCLC patients who underwent curative pulmonary resection. The control g
Background Balloon kyphoplasty is a minimally invasive procedure for the treatment of painful vertebral fractures, which is intended to reduce pain and improve quality of life. We assessed the efficacy and safety of the procedure. Methods Adults with one to three acute vertebral fractures were eligible for enrolment in this randomised controlled trial at 21 sites in eight countries. We randomly as
The International Collaboration of Epidemiological Studies of Cervical Cancer has combined individual data on 11,161 women with invasive carcinoma, 5,402 women with cervical intraepithelial neoplasia (CIN)3/carcinoma in situ and 33,542 women without cervical carcinoma from 25 epidemiological studies. Relative risks (RRs) and 95% confidence intervals (CIs) of cervical carcinoma in relation to numbe
Aim: To explore the prevalence of atrial fibrillation in patients with hypertension and type 2 diabetes and to identify possible mechanisms for the development of atrial fibrillation. Methods: A community-based, cross-sectional observational study was conducted in the primary health care in Skara, Sweden, and 1739 subjects (798 men, 941 women) were surveyed. Patients were categorized as those wit
Comparative study of the Swedish sex education film "Kärlekens språk" (2004). Particular focus is given narration, reflexivity and sexuality.
1. We examined the temporal and spatial heterogeneity of zooplankton in lake surface waters during the spring of 3 years in Lake Washington, U.S.A., a large lake with a high production of sockeye salmon fry. 2. We show large within-season and among-year variation in the horizontal distribution of temperature, chlorophyll a concentration, and zooplankton in the lake. The main pattern, a delay in zo
The present study was undertaken to ascertain the frequency of cytogenetic polyclonality in various hematologic malignancies and to investigate whether morphologic subgroup, age, gender, or previous genotoxic exposure influences the incidence. Among 2,243 cytogenetically investigated hematologic malignancies, 10 acute myeloid leukemias (AML), 5 myelodysplastic syndromes (MDS), 2 acute lymphoblasti
BACKGROUND AND PURPOSE: The control of balance is vital in many sporting activities as well as in activities of daily life. In order to treat deficiencies properly valid and reliable methods are needed to evaluate different aspects of stability. Muscle fatigue has been proposed to cause a change in postural control strategy, and the use of different tools and variables might therefore elucidate th
Men with prostate cancer (n=25) were interviewed, focusing on experiences of micturition problems, indwelling catheter treatment and sexual life consequences. Narrations were found to be practical and technical descriptions rather than emotional, and experiences were described with reduction and negligence regarding personal well-being and the impact of problems. Phenomenological-hermeneutic analy
An integrative approach to managing host–parasite interactions that threaten species communities will benefit from identifying variation in parasite impact across host species, and host–parasite responses to annual climatic variation. We examine interannual, inter- and intraspecific variation in Philornis downsi intensity – an introduced blood sucking fly that causes high fitness costs in Darwin’s
Relapsing polychondritis ( RP) is an autoimmune disease that affects extra-articular cartilage. Matrilin-1-induced relapsing polychondritis (MIRP) is a model for RP and is useful for studies of the pathogenic mechanisms in this disease. There are indications that the major histocompatibility complex (MHC) class II plays a major role in RP, since DR4(+) patients are more commonly affected than cont
This master’s thesis in Sociology of Law aimed to examine how plural legal orders and discourses work in Myanmar and how they influence the Rohingya Muslims’ legal status and identity. The research of this thesis was conducted by analysing various documents from international and national actors involved in the processes in Rakhine. The objective of this thesis was to reach my set aim by conductin
The Sami are one of the world’s indigenous peoples that live in a land area referred to as Sápmi that extends over the north of Sweden, as well as parts of Norway, Finland and Russia. Part of the Sami population in Sweden lives according to their traditional way of life which includes reindeer husbandry, hunting, fishing, and other resource-based activities. It is internationally recognized that i
The aim of this thesis is to gain a deeper understanding of pupil participation from the perspective of psychological wellbeing through analysing school policy discourse related to the reformation of the Swedish upper secondary school in 2011 (Gy11) and interviews with Swedish upper secondary school counsellors. Participatory learning is part of a new educational paradigm and coincides with Articl
Sustainability has long been serving dominant political and economic interests under the guise of sustainable development. This political and economic co-option of sustainable development has given rise to a new slogan: “system change, not climate change”. Our crisis is no longer just an environmental one, but a structural one, in which our means of living have outdistanced the ends for which we l
Background: For most patients with end stage renal disease (ESRD) kidney transplantation is the best treatment option. Best outcomes are achieved with living donation. To increase access to living donation for patients who are not compatible with their living donors, Kidney Exchange Programs (KEPs) have evolved. By exchanging donors, compatibility can be achieved thus enabling transplantation.
This thesis focusses on three distinct unevenness’s seen within the Covid-19 pandemic. Geographical unevenness shows in an uneven spread in and between countries. Societal unevenness is seen as Covid-19 deaths mainly occur in the elderly population, or people with underlying conditions. Finally, governmental policy unevenness is seen between countries as some have imposed strict health measures, a
