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Aim: The Swedish Renal Registry (SRR) is a unique national quality registry that monitors the clinical trajectory of patients with chronic kidney disease (CKD). We have validated the biopsy data registered in the SRR for IgA Nephropathy (IgAN) diagnosis. Methods: In total 25% of all patients (n = 142), registered with IgAN in the SRR after having performed a kidney biopsy during 2015–2019, were ra
A data-driven method combined with the formulations of boundary integral equations is developed for the frequency-domain analysis of parametrized acoustic systems, arising from the spatial discretization of the linear Helmholtz equation. The method derives surrogate models for the approximation of frequency response functions at selected field points via the construction of neural networks with ra
The MAX IV Laboratory, inaugurated in 2016, hosts a 3 GeV ultra-low emittance storage ring, a 1.5 GeV storage ring and a linear accelerator driven Short Pulse Facility to deliver synchrotron radiation to scientific users. A Stability Task Force has been assigned to ensure the delivery of stable beams since early on in the design phase of the laboratory and is continuing its work in an ongoing and
This chapter assess the state of brass instruments and their associated repertoire and performance practices in the early twenty-first century. Technological innovations and manufacturing developments from recent decades are outlined, as well an examination of how performance techniques have evolved and adapted to meet the demands of modern musicians. Finally, an overview is given of contemporary
Animal migration has fascinated scientists and the public alike for centuries, yet migratory animals are facing diverse threats that could lead to their demise. The Anthropocene is characterised by the reality that humans are the dominant force on Earth, having manifold negative effects on biodiversity and ecosystem function. Considerable research focus has been given to assessing anthropogenic im
In this talk recent progress in studying the short-distance properties of the hadronic light-by-light contribution to the muon g−2 is described. The intermediate and short-distance part contributes a large part of the error of the theoretical prediction as described in the white paper [1]. We showed that the massless quark-loop is the first term in a systematic expansion at short-distances, a resu
Inflammation and autoimmunity are known as central processes in many skin diseases, including psoriasis. It is therefore important to develop pre-clinical models that describe disease-related aspects to enable testing of pharmaceutical drug candidates and formulations. A widely accepted pre-clinical model of psoriasis is the imiquimod (IMQ)-induced skin inflammation mouse model, where topically ap
The recent history of Sudan, as is evident from the strict international relevance and the tragic events linked with the birth of South Sudan in July 2011, has been punctuated by an endless series of abuses, inter-ethnic tensions and sectarian conflicts. The multi-ethnic composition and the evident religious disparities among the populations residing in the northern and southern regions of Sudan h
Abstract Ten-a is one of the two Drosophila proteins that belong to the Ten M protein family. This protein is a type II transmembrane protein and is expressed mainly in the embryonic CNS, in the larval eye imaginal disc and in the compound eye of the pupa. Here, we investigate the role of ten-a during development of the compound eye by using the Gal4/UAS system to induce ten-a overexpression in th
The formalism developed in molecular theory for calculation of local electronic-structure characteristics in a nonorthogonal atomic basis is generalized to systems with translational symmetry. Expressions have been derived to describe the bond orders, covalency, and valence in a crystal for restricted and unrestricted Hartree-Fock methods. Nonempirical electronic-structure calculations and an anal
A new quantum-chemical definition is given of the full atomic valence taking into account both the covalent and ionic parts of the chemical bonds formed by an atom in molecules and crystals. Full valence is close to formal ("classical") valence of an atom in a wide row of compounds. The theoretical consideration and the CNDO calculations of molecules and crystals are made to justify the validity o
Chyle and chylomicrons, obtained after feeding thoracic duct cannulated rats [3H]arachidonic (20:4) and [14C]linoleic acid (18:2) in cream, were injected i.v. into recipient animals. 7.5-15 min after injection, the 14C/3H ratio of the triacylglycerols remaining in plasma was about half of that in the injected chylomicrons, indicating that the chylomicron remnants formed retained relatively more [3
[3H]retinal- or [3h]cholesterol- and [14C]fatty acid-labeled chylomicrons and chylomicron remnants were injected intravenously into normal rats and rats subjected to partial or total obstruction of the bile duct 8 or 48 h earlier. The clearance from plasma of the [3H]retinyl and the [3H]cholesteryl esters in 30-120 min was markedly decreased in rats with total obstruction, and the uptake of 3H by
