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The ability to detect and quantitate biomolecules in complex solutions has always been highly sought-after within natural science; being usedfor the detection of biomarkers, contaminants, and other molecules of interest. A commonly used technique for this purpose is the Enzyme-linked Immunosorbent Assay (ELISA), where often one antibody is directed towards a specific target molecule, and a second

When applying conventional immunological assays involving the use of a labeled moiety, sensitivity is gained at the expense of time since equilibrium conditions are a prerequisite for such assays. Since an analysis in this sense may take from several hours to a few days,1,2 much effort has been made lately to shorten the time of assay. This has also (as will be discussed later in the chapter) been

Meristem Wall is a prototype for a 3D-printed building envelope, featuring a dynamically controllable network of integrated air channels that allow a fluid and adaptive relationship between inside and outside. The wall integrates functional lighting and electricity, windows, and a custom CNC-knitted textile interior. It is fabricated through binder-jet sand 3D printing and points towards a climati

Gastrointestinal motility disorders are common in childhood and in this thesis we look at two of them, i.e. Hirschsprung´s Disease (HD) and gastroesophageal reflux disease (GERD) in five different studies. HD is a congenital disease characterized by an abscence of ganglion cells in myenteric and submucous ganglia, most commonly in the distal part of the large bowel. In Paper I, we have studied th

Popular Abstract in Swedish Den här avhandlingen har behandlingsresultaten av permanent djupelektrod stimulering i hjärnan (Deep Brain Stimulation, DBS) undersökts ur såväl symptomminsknings som patients och närståendes perspektiv. DBS behandling innebär att en elektrod med fyra poler opereras in i hjärnan genom ett litet hål i skallbenet, och den kopplas till pulsgivardosa. Hela systemet är doltThe treatment related effects and personalized goal fulfilment of Deep Brain Stimulation (DBS) have been assessed in studies with different designs. The brain targets included the thalamus for medically intractable tremor in Parkinson's disease (PD) or essential tremor (ET) and the subthalamicus for reducing hypo-, bradykinesia, tremor, rigidity and dystonia in PD. A Swedish multi-center study sh

A calibration model was developed for a non-invasive blood glucose sensor, to determine how the blood glucose data measured by this sensor is related to blood glucose data measured with laboratory capillary finger sticks and to corrupting noise. The variability of calibration models for different patients was analyzed as well as the dynamics of the non-invasive blood glucose sensor according to re

Gambling and the national gambling markets has so far not been harmonised through any Community law regulation or directive. Instead gambling is covered by the general principles of Community provisions for the free movement of services article 49, and the closely connected article 43 regulating the freedom of establishment. This has been established through the case law of the ECJ. The Member Sta

Helicobacter pylori is able to utilize several lectin-like, protein-carbohydrate interactions for binding to mucins, cell surfaces, and extracellular matrix proteins. As determined by hemagglutination assays and binding of radiolabeled bacteria to glycosphingolipids on thin-layer chromatograms, strains of gastric helicobacters and enterohepatic helicobacters, including Helicobacter canis, Helicoba