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A folding variant of human alpha-lactalbumin induces mitochondrial permeability transition in isolated mitochondria

A human milk fraction containing multimeric alpha-lactalbumin (MAL) is able to kill cells via apoptosis. MAL is a protein complex of a folding variant of alpha-lactalbumin and lipids. Previous results have shown that upon treatment of transformed cells, MAL localizes to the mitochondria and cytochrome c is released into the cytosol. This is followed by activation of the caspase cascade. In this st

Certain humans, certain animals : attitudes in the long term

Do certain humans and animals have greater value than other humans and animals? The question will be discussed using some examples from pre-Christian burial practices and other depositions of human and animal bones in Scandinavia. During the pre-Christian period it seems that certain humans and certain animals were buried in graves made for the purpose, while other humans and animals were deposite

Ad Experimentum - En observation och analys av Andra Vatikankonciliets diakonatreform med särskild hänsyn till det förnyade diakonatets identitets- och legitimitetsproblematik.

This dissertation examines the renewal of the diaconate since the Second Vatican Council 1962 to 1965, focusing on the problem of the new diaconate to establish an identity within the ministry and to gain legitimacy both from the priesthood and the laity. The thesis brings forth the idea that the fathers of the Council decided to carry out the reform as an experiment after receiving a proposal to

Mannose-binding lectin as a risk factor for acute coronary syndromes.

Background. Mannose-binding lectin (MBL) is a multifunctional protein involved in innate immunity. We tested whether MBL and elevated viral and bacterial antibodies were risk factors for acute coronary events. Design. Controlled cohort study. Methods. A total of 354 patients with unstable angina pectoris (UA) or acute myocardial infarction (AMI) were compared with 334 paired controls. Results. Ent

Fully integrated wireless inductive tongue computer interface for disabled people

This work describes a novel fully integrated inductive tongue computer interface for disabled people. The interface consists of an oral unit placed in the mouth, including inductive sensors, related electronics, a system for wireless transmission and a rechargeable battery. The system is activated using an activation unit placed on the tongue, and incorporates 18 inductive sensors, arranged in bot

Standardization and Innovation within the Green Buildings field: Insights from Europe

A research project was conducted by the two PhD students Markus Arnez Wegelius and Philip Hedestad from the Standardisation Research Centre, within the Institute of Economic Research at Lund University, Sweden, and with the supervision of Mr. Daniele Gerundino, Strategic Adviser to the Secretary-General (ISO). The project was sponsored by ISO (The International Organization for Standardization), N

Managing human fear of bears and wolves

Decision-makers and managers spend substantial amounts of funding everyday on various interventions aimed at management of the large carnivores, for example different measures to mitigate depredation on livestock, e.g., removal of carnivores and fencing of livestock (see Linnell et al. 1996 for an extensive review). Management of species that occur in low numbers is challenging as relatively small

Topography, hydrology and Spartina alterniflora growth range for restored salt marsh Elders Point East, Jamaica Bay, New York

Restored salt marsh; topography, hydrology and vegetation Coastal salt marshes are shaped through a combination of physical (i.e., sediment accumulation/erosion) and biological (i.e., vegetation) processes. They are characterized by fine sediments and halophytic vegetation. The accretion rate and elevation change has been indicated as one of the most important factors in ecology of the marshes. T

The role of P fimbriae for Escherichia coli establishment and mucosal inflammation in the human urinary tract

Popular Abstract in Swedish Infektioner i urinvägar, tarm och luftvägar orsakas av bakterier som speciellt anpassats till respektive vävnad. Infektionen börjar med att bakterien binder till slemhinneytan, och därmed sätter igång inflammation och försvar. Urinvägsinfektioner (UVI) är en värdefull modell för att förstå de molekylära detaljerna som avgör balansen mellan värd och bakterie. UVI orsakaBacterial adhesion to the bladder mucosa is a critical step for the establishment of Escherichia coli bacteriuria. The P-fimbriae, encoded by the pap gene cluster, are considered as virulence factors but the mechanisms have been debated. This study defined the roles for P fimbriation during the early colonization of the human urinary tract. Patients with recurrent UTI were first subjected to deli

Adm Guide 2022 Svenska

Guide 2022 in Swedish Guide 2022 CEC 2022/01/28 Ekonomi Budget i ansökan Görs i samråd med ekonom (Eva.stengard@cec.lu.se) Upprättande av fullkostnadskalkyl (fkk) vid ansökan Innan ansökan skickas iväg ska fullkostnadskalkyl upprättas och skrivas under av prefekt och ekonom. Görs i samråd med ekonom (Eva.stengard@cec.lu.se) Länk till information om ansökansprocessen: CEC-Medarbetare - ansöka om fo

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/2022-01/Adm%20Guide%202022%20Svenska.xlsx - 2025-10-17

Styrelsen 2022-05-17 Protokoll

CAMPUS HELSINGBORG PROTOKOLL Sammanträdesdatum 2022-05-17 Sida 1 av 5 Diarienummer sTYR2022lt243LuNos UNIVERSITET Utveckl i ngsen hete n Protokoll Campus Helsingborgs styrelse Närvarande ledamöter Lena Eskilsson Charlotta Johnsson Christofer Edling, lämnade vid punkt l2 Annika Olsson Patrik Lindskoug Kristina Åkesson, digitalt Olof Sundin Mattias Wengelin Mozghan Zachrison anslöt vid punkt 8 Peter

https://www.ch.lu.se/internt/sites/ch.lu.se.internt/files/2023-11/Styrelsen%202022-05-17%20protokoll.pdf - 2025-10-17

Immunological aspects of latent tuberculosis infection during pregnancy

Pregnancy-induced immune modulation might lead to reactivation of latent tuberculosis infection (LTBI). This thesis explores aspects of immune-based LTBI diagnostics and how pregnancy affects the immune control of Mycobacterium tuberculosis (Mtb) infection. We studied a prospective cohort of women recruited during pregnancy in Ethiopia. LTBI testing was performed by quantification of interferon-γ

The skåne emergency medicine (SEM) cohort

BACKGROUND: In the European Union alone, more than 100 million people present to the emergency department (ED) each year, and this has increased steadily year-on-year by 2-3%. Better patient management decisions have the potential to reduce ED crowding, the number of diagnostic tests, the use of inpatient beds, and healthcare costs.METHODS: We have established the Skåne Emergency Medicine (SEM) co

Meristem wall : an exploration of 3d-printed architecture

Meristem Wall is a prototype for a 3D-printed building envelope, featuring a dynamically controllable network of integrated air channels that allow a fluid and adaptive relationship between inside and outside. The wall integrates functional lighting and electricity, windows, and a custom CNC-knitted textile interior. It is fabricated through binder-jet sand 3D printing and points towards a climati

The Maternal Group B Streptococcus Alpha-Like Protein Subunit Vaccine GBS-NN Targets Homotypic and Heterotypic Strains, Confers Opsonophagocytic Killing and Prevents in vitro Invasion of Human Epithelial Cells

Maternal vaccination, resulting in transfer of protective IgG across the placenta, represents a promising strategy to prevent neonatal disease caused by group B Streptococcus (GBS). The prototype vaccine GBS-NN, a fusion protein consisting of the N-terminal domains of the alpha-like protein (Alp) family members AlphaC and Rib, has been shown to display a good safety profile and to elicit a strong

Direct activation of a bacterial innate immune system by a viral capsid protein

Bacteria have evolved diverse immunity mechanisms to protect themselves against the constant onslaught of bacteriophages1-3. Similar to how eukaryotic innate immune systems sense foreign invaders through pathogen-associated molecular patterns4 (PAMPs), many bacterial immune systems that respond to bacteriophage infection require phage-specific triggers to be activated. However, the identities of s