Filtyp
Brexit and the ensuing uncertainty about the United Kingdom’s (UK’s) future relationship with the European Union (EU) have brought the participation of non-EU Member States in the internal market to the centre of academic attention. The latter phenomenon is not novel and many of the existing frameworks for cooperation between the EU and its neighbourhood countries have been used as models for a po
AIMS: Improved risk stratification is of value for decision making in pulmonary arterial hypertension (PAH). Right heart catheterization combined with quantitative tricuspid regurgitation (TR) by cardiovascular magnetic resonance (CMR) may provide this. The aims were to study: (i) to what extent quantitative TR is associated with event-free survival; (ii) how quantitative TR is related to known pr
Mutations in the FMS-like tyrosine kinase 3 (FLT3) gene in 13q12.2 are among the most common driver events in acute leukemia, leading to increased cell proliferation and survival through activation of the PI3K/AKT, RAS/MAPK and STAT5 signaling pathways. In this study, we examine the pathogenetic impact of somatic hemizygous 13q12.2 microdeletions in B-cell precursor acute lymphoblastic leukemia (B
In this chapter we will describe applications of latent semantic analysis to assess semantic linguistic maturity in children and how well the method can predict whether a child has developmental language disorder (DLD), based on orally produced narratives. Assessment of narrative ability in preschool years captures important cognitive, linguistic and socio-pragmatic skills and is an important prog
The function of proteins is influenced not only by the atomic structure but also by the detailed structure of the solvent surrounding it. Computational studies of protein structure also critically depend on the water structure around the protein. Herein we compare the water structure obtained from molecular dynamics (MD) simulations of galectin-3 in complex with two ligands to crystallographic wat
Analytical-scale extraction and chromatography of oils, fats and other liposoluble compounds can be achieved by using supercritical carbon dioxide as a solvent. Since the 90's when supercritical fluid chromatography (SFC) was a hot topic, this technology has developed into a robust, modern analytical technique that uses any proportions of compressed CO2 mixed with an organic solvent. Supercritical
Human language involves combining items into meaningful, syntactically structured wholes. The evolutionary origin of syntactic abilities has been investigated by testing pattern perception capacities in nonhuman animals. New World primates can respond spontaneously to structural changes in acoustic sequences and songbirds can learn to discriminate between various patterns in operant tasks. However
Dietary fiber residues were prepared from the cooked seeds of eleven legume varieties, following the AOAC enzymatic method. Resistant starch associated to fiber, i.e. retrograded resistant starch (RS), was assessed after alkaline dispersion of the indigestible residues. All legumes contained significant amounts of RS, ranging between 3.0% (g per 100g cooked seed on dry matter basis) in red cowpeas
Purpose: The objective was to investigate if the gonadotropin receptor variants N680S (N: asparagine, S: serine, rs6166) in the follicle-stimulating hormone receptor (FSHR) and N312S (rs2293275) in the luteinizing hormone/human chorionic gonadotropin receptor (LHCGR) predicted cumulative live birth rate after in vitro fertilization (IVF). Methods: A total of 665 women were consecutively enrolled f
Hydropower is a major energy source in Sweden, and proper reservoir management prior to the spring-flood onset is crucial for optimal production. This requires accurate forecasts of the accumulated discharge in the spring-flood period (i.e. the spring-flood volume, SFV). Today's SFV forecasts are generated using a model-based climatological ensemble approach, where time series of precipitation and
The ambition of this two-part article is to argue for immanent critique as a research strategy in sustainability studies. We do this by picking up and developing two central, cross-cutting themes in sustainability research, namely interdisciplinarity and normativity. It is widely suggested that the problem-driven and solution-focused orientation in sustainability studies necessitates interdiscipli
Innovation is essential in the complex and fluid social environment of tourism; for the practitioner, the essential capability is that of being able to learn and innovate, and to do so often. One must therefore reflect on how present methods of university education might equip tourism students (or indeed students in any social science) to develop the necessary innovation capability so as to meet t
As climate change research becomes increasingly applied, the need for actionable information is growing rapidly. A key aspect of this requirement is the representation of uncertainties. The conventional approach to representing uncertainty in physical aspects of climate change is probabilistic, based on ensembles of climate model simulations. In the face of deep uncertainties, the known limitation
For memory retrieval, pattern completion is a crucial process that restores memories from partial or degraded cues. Neurocognitive aging models suggest that the aged memory system is biased toward pattern completion, resulting in a behavioral preference for retrieval over encoding of memories. Here, we built on our previously developed behavioral recognition memory paradigm—the Memory Image Comple
AIM: To describe how women smokers with newly diagnosed breast cancer experienced brief preoperative smoking cessation intervention in relation to breast cancer surgery. BACKGROUND: Preoperative smoking cessation intervention is relevant for short- and long-term risk reduction in newly diagnosed cancer patients. Our knowledge of how patients with malignant diagnoses experience preoperative smoking
The first step of handling health promotion (HP) in Diagnosis Related Groups (DRGs) is a systematic documentation and registration of the activities in the medical records. So far the possibility and tradition for systematic registration of clinical HP activities in the medical records and in patient administrative systems have been sparse. Therefore, the activities are mostly invisible in the reg
OBJECTIVE: Depression has been associated with diabetic retinopathy and increased plasma levels of galectin-3, a lectin expressed in activated macrophages. Increased levels of sCD163, the soluble form of a macrophage expressed scavenger receptor involved in several inflammatory processes, have been demonstrated in the vitreous of the eye in type 1 diabetes (T1D) patients with severe diabetic retin
Objective: ACTH is considered a weak marker for autonomous cortisol secretion (ACS) in patients with adrenal incidentalomas (AIs). Our aim was to investigate suppressed basal ACTH as a marker of ACS and to elucidate why this criterion is of limited value. Methods: Basal ACTH and cortisol after overnight dexamethasone suppression test (cortisolONDST) were measured in 198 patients with unilateral AI
We used the nation-wide Swedish Family-Cancer Database to examine the risk for testicular cancer in offspring through parental and sibling probands. Among 0-68-year-old offspring, 4082 patients had testicular cancer in years 1961-2000, among whom 68 (1.67%) had an affected father/brother. Standardized incidence ratios (SIRs) for familial risk were four-fold when a father and nine-fold when a broth
High or low ambient temperatures pose a risk factor for the worsening or onset of psychiatric disorders. The aim of this study was to investigate the association between ambient temperature and psychiatric emergency visits in an urban region in a temperate climate. The daily number of visits to a psychiatric emergency room (PEVs) at Sahlgrenska University Hospital, Gothenburg, Sweden and the daily
