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Hormone-sensitive lipase (HSL) is the rate-limiting enzyme in lipolysis. Stimulation of rat adipocytes with isoproterenol results in phosphorylation of HSL and a 50-fold increase in the rate of lipolysis. In this study, we used site-directed mutagenesis and two-dimensional phosphopeptide mapping to show that phosphorylation sites other than the previously identified Ser-563 are phosphorylated in H

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Seventy-three Swedish blood donors (52 men, 21 women; median age 36 years) repeatedly reactive for hepatitis C antibodies (anti-HCV C-100-3) were tested with a second-generation (2nd-gen) anti-HCV Elisa and a 4-band recombinant immunoblot assay (RIBA 2). These results were correlated to serum alanine aminotransferase (S-ALAT), liver morphology and viremia as detected by 'nested' polymerase chain r

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A search is presented for the direct pair production of a chargino and a neutralino [Formula: see text], where the chargino decays to the lightest neutralino and the [Formula: see text] boson, [Formula: see text], while the neutralino decays to the lightest neutralino and the 125 GeV Higgs boson, [Formula: see text]. The final states considered for the search have large missing transverse momentum

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Aim To investigate how the chemical composition of native organic matter of two contrasting soils varies with inputs of biochar and fresh material (including plant roots) and how these underlying changes influence microbial community structure. Methods Corn stover (CS) and CS-derived biochars produced at 350 °C and 550 °C were applied at a dose of 7.2 t C ha−1 to two contrasting soils—an Alfis

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Utilities, such as steam and cooling water, are often shared between production areas at large-scale sites. A disturbance in the supply of a utility is therefore likely to affect a large part of a site, and cause great loss of revenue. This study focuses on identifying disturbances in utilities and estimating the economical effects of such disturbances. A general method for reducing the loss of re

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The complex genetics of cancer, which allows tumours to grow and spread while bypassing the control circuitry of the cell, involves dysregulation of the genome, transcriptome and proteome. The importance of protein-coding genes such as growth factors and hormone receptors is well established. Recently, non-coding RNAs have emerged as important players in tumour development with potential to be exp

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Context: Secondary hypogonadism is common in aging men; its natural history and predisposing factors are unclear. Objectives: The objectives were 1) to identify factors that predispose eugonadal men (T >= 10.5 nmol/L) to develop biochemical secondary hypogonadism (T < 10.5 nmol/L; LH <= 9.4 U/L) and secondary hypogonadal men to recover to eugonadism; and 2) to characterize clinical features associ

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Småvatten är trots sin ringa storlek ekologiskt betydelsefulla och fungerar som habitat för många arter. För groddjur spelar de en avgörande roll för fortplantningen eftersom småvatten används som lekmiljö. Populationer av groddjur minskar idag över hela världen och två av de största hoten mot groddjur är habitatförlust och habitatfragmentering. I Sverige har många småvatten försvunnit som en effeDespite their size, small ponds are ecologically important and act as a habitat for many species. For amphibians they play a significant role for reproduction given that ponds are used as breeding sites. At present amphibian populations are decreasing worldwide and two of the biggest threats they face are habitat destruction and habitat fragmentation. In Sweden many small ponds have disappeared ov

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This thesis focuses on the exchange of experience, knowledge and strategies between local social movements resisting large scale mining projects. While the exchanges between local movements and supralocal movements, international organizations and NGOs has been studied, less attention is payed to the role of collaborations between local movements themselves. A case study based on fieldwork and int

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Sandvik SRP AB in Svedala has recently made a big investment in a completely new production facility that is called Greenfield. The facility will be ready for production in 2013 and will have eleven top modern axle lathe- and vertical boring milling machines. The machines will process casting to parts for the stone crushers Sandvik SRP in Svedala manufacture. The goal with Greenfield is to get wor

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En grundläggande målsättning i svensk rätt är att barnets bästa ska sättas i främsta rummet och det ska alltid ske utifrån barnets individuella förhållan-den. Umgänge bedöms som utgångspunkt vara bra för barnet. Barn har rätt och behov av att träffa båda sina föräldrar och umgänge ska ske under trygga former. Genom att analysera och kombinera det som anses vara bra för barnet, barnets vilja, barneA basic aim in swedish law is the ”best for the child” always should be giv-en first priority from an individual child perspective. Parental visitation rights are assessed according to what is best for the child. Children have right and also need to see both their parents under safe and secure forms. Through an analysis of what is reasonably good for the child, the child’s own will and need, the b

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Tall buildings have lately become a problem to design because of the development of light weighted steel frames and wind loads. An important task of a structure is the absorption of horizontal loads and the capacity to transfer the resulting moment down into the ground. It is the engineer’s task to make sure that the structure’s performance is sufficient when it comes to safety and serviceability.

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Swedish buildings, which were built in the early 60: s to mid 70: s are in great need of a restoration. Not least in view of the considerable quantities of energy that the buildings consume, this is partly due to the end of life in building components. Energy which in the worst case is obtained from non-renewable energy sources, which in turn generates significant carbon dioxide emissions worldwid

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China is a mega-diversity country with abundant natural resources, and the richness of these resources is demonstrated to be relevant with the local people’s historical interactions between biophysical and sociocultural systems. If we are to maintain biodiversity and strike a balance between human well-being and ecosystem service, it is important to incorporate the local people and their tradition

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Gräsrotsfinansiering är en finansieringsform som växer i omfattning och popularitet. Kortfattat handlar det om att bolag söker kapital från den stora massan istället för de mer traditionella källorna. Det finns flera varianter av gräsrotsfinansiering, den som vållar de största juridiska spörsmålen är den delägarbaserade varianten. Denna innebär att investerare erbjuds aktier eller andra värdepappeCrowdfunding is a form of financing that grows in scope and popularity. In short, it is about companies seeking capital from the crowd instead of the more traditional sources. There are several different forms of crowdfunding. The one who mainly causes the legal questions is the equity form. This means that companies offer shares or other securities in, usually private, limited liability companies

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Rättsläget kring implementeringen av IPRED-direktivet har varit osäkert och omtvistat. Förhållandet mellan upphovsrätt och integritet är invecklat och skyddet för de ekonomiska rättigheterna har varit i behov av förbättring samtidigt som att säkrandet av tryggheten för personlig information i ett växande informationssamhälle blivit allt större. Genom domen i ePhone-målet har det fastslagits att dThe legal position regarding the implementation of the IPRED directive has been uncertain and controversial. The relationship between copyright and privacy is complex and protection of the economic rights has been in need of improvement, while the same thing can be argue for safeguarding of the security of personal information in the growing information society. The ruling in the Ephone case has

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Uppsatsen undersöker frågan samebyars avtalsrätt. Frågan är intressant eftersom samebyar i viss mån kan jämföras med ekonomiska föreningar. Juridiska personer har vanligtvis avtalsfrihet, men samebyars möjligheter är begränsade. Enligt ren-näringslagen får samebyarna inte ingå avtal om upplåtelse, och det är endast rege-ringen som får förordna om ett upphörande av renskötselrätten. År 2020 medde-lThis essay examines the contractual capacity of Sámi villages. While these villages are, in legal terms, comparable to economic association and thus possess legal personality, their ability to enter into agreements is subject to legal constraints. Unlike typical legal entities Sámi villages are not free to contract as they wish. Under the Reindeer Husbandry Act, Sámi villages are prohibited from g

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The situation for the environment is in many ways dire. However, amidst all the negative environmental developments it is easy to neglect the successes that have actually happened. With the aim of better understanding what factors facilitated such a success this thesis analyses one such case, namely emissions of dioxins and chlorinated waste from the pulp and paper industry in Sweden. Dioxins were

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Syftet med studien var att undersöka förhållandet mellan självförverkligande, socialt jämförande och motivation. För socialt jämförande mättes både en generell benägenhet och benägenhet att jämföra i olika riktningar (uppåt eller nedåt). Den operationella definitionen för motivation utgick ifrån de kausalitetsorienteringar som återfinns inom self-determination theory. Datainsamling skedde i form aThe purpose of this study was to investigate the relationship between self actualization, social comparison, including upward and downward comparison, and different types of motivation as defined by the proposed causality orientations within self determination theory. Data was acquired through a survey distribution. The sample consisted of a convenience sample (N=131). The results, from a correlat