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Association of the calpain-10 gene with type 2 diabetes in Europeans: Results of pooled and meta-analyses

We conducted pooled and meta-analyses of the association of the calpain-10 gene (CAPN10) polymorphisms SNP-43, Indel-19 and SNP-63 individually and as haplotypes with type 2 diabetes (T2D) in 3237 patients and 2935 controls of European ancestry. In the pooled analyses, the common SNP-43*G allele was associated with modest but statistically significant increased risk of T2D (odds ratio (OR) = 1.11

Injury markers predict time to dementia in subjects with MCI and amyloid pathology.

OBJECTIVES: Alzheimer disease (AD) can now be diagnosed in subjects with mild cognitive impairment (MCI) using biomarkers. However, little is known about the rate of decline in those subjects. In this cohort study, we aimed to assess the conversion rate to dementia and identify prognostic markers in subjects with MCI and evidence of amyloid pathology. METHODS: We pooled subjects from the VU Un

Weight-change as a prognostic marker in 12 550 patients following acute myocardial infarction or with stable coronary artery disease.

Aims To examine the prognostic importance of weight-change in patients with coronary artery disease (CAD), especially following acute myocardial infarction (AMI). Methods and results In 4360 AMI patients (OPTIMAAL trial) without baseline oedema, we assessed 3-month weight-change, baseline body mass index (BMI), demographics, patient history, medication, physical examination, and biochemical analys

Continuous amplitude-integrated electroencephalogram predicts outcome in hypothermia-treated cardiac arrest patients.

OBJECTIVE:: To assess the prognostic value of continuous amplitude-integrated electroencephalogram in comatose survivors after cardiac arrest and treated with hypothermia. DESIGN:: Prospective observational study. SETTING:: General intensive care unit at a university hospital. PATIENTS:: Comatose patients after cardiac arrest and treated with hypothermia. INTERVENTIONS:: Patients were sedated and

Clinically Assessed Mediolateral Knee Motion: Impact on Gait.

OBJECTIVE: Mediolateral knee movement can be assessed visually with clinical tests. A knee-medial-to-foot position is associated with an increased risk of knee injuries and pathologies. However, the implications of such findings on daily tasks are not well understood. The aim of this study was to investigate if a knee-medial-to-foot position assessed during a clinical test was associated with alte

Social Class in Science Class

Abstract in Chinese 概述 学校教学最重要目的之一是赋予每个孩子同等的教育. 尽管如此, 学校再创造了社会差异. 先前的研究表明,学生的低下社会经济情况背景与自然学科成绩低下有一定联系. 这样, 不少学生在未来就被排斥在社会高端学科的教育和职业之外. 本篇论文在Bourdieu和Bernstein的理论基础上, 以自然学科课堂的社会阶级为中心, 旨在对小 学生所受的教育存在不等现象提供更多方位描述和更深层的分析. 在人种民族学的启发下, 本论文的数据取自瑞典义务小学八年级物理教室里的观察, 记录, 采访和统计调查. 1. 对教室里现象的描述和分析揭示了知识难度的下降. 这一现象的发生通常是因为自然学科的教学所具有的社会历史传统因素, 学生, 老师和教室里的谈话社交之间有无形的默契, 或被称为隐蔽的磋商, (出发点往往是善良的愿望),教室里形成了对所有学生都不利的知识难度的The overall aim of this thesis was to contribute to a more complex and multi-faceted description and analysis of inequalities in education, focusing on social class in the science classroom. Inspired by an ethnographic approach, the data was produced through observations, field notes, interviews, and a questionnaire in a Swedish compulsory school. The students aged fourteen and fifteen, were follo

Handläggningsordning Vid JF 2020-05-27

Handläggningsordning Juridiska fakulteten 2020 BESLUT 2020-05-27 Dnr STYR 2020/783 Juridiska fakultetsstyrelsen Postadress Box 207 221 00 Lund Besöksadress Lilla Gråbrödersgatan 4 Telefon dir 046-222 10 00, växel 046-222 00 00 Telefax 046- 222 11 61 E-post info@jur.lu.se Internet http://www.jur.lu.se Handläggningsordning vid Juridiska fakulteten avseende Lunds universitets anställningsordning Denn

https://www.jur.lu.se/sites/jur.lu.se/files/2023-03/Handl%C3%A4ggningsordning%20vid%20JF%202020-05-27.pdf - 2026-05-09

Geon06 course analysis ht2019

Course analysis GeoN06, autumn 2019 Course leader: Anne Birgitte Nielsen GeoN06 is a master’s level course open to students from geology, archaeology, geography, biology and related subjects. The course is built around a project work running through the course and a series of lectures by different teachers, with different specializations within paleoecology and related methodologies. All seven stu

https://www.geology.lu.se/sites/geology.lu.se/files/geon06_course_analysis_ht2019.pdf - 2026-05-09

Prevalence of depression, anxiety, fatigue, and headache before and after long COVID onset : a case-control study in the total population of Region Stockholm

BACKGROUND: Post-acute sequelae of SARS-CoV-2 infection, or long COVID, include diverse symptoms and remain a major concern worldwide. This study investigates the occurrence of depression, anxiety, fatigue, and headache 1 year prior to the COVID-19 pandemic (2019), 12 months prior to, and 6 months after long COVID diagnosis in individuals diagnosed with long COVID and matched population-based cont

Eighteen-year follow-up of the Göteborg Randomized Population-based Prostate Cancer Screening Trial : effect of sociodemographic variables on participation, prostate cancer incidence and mortality

Objective: This study examined whether previously reported results, indicating that prostate-specific antigen (PSA) screening can reduce prostate cancer (PC) mortality regardless of sociodemographic inequality, could be corroborated in an 18 year follow-up. Materials and methods: In 1994, 20,000 men aged 50–64 years were randomized from the Göteborg population register to PSA screening or control

Otillbörlig förmån - En undersökning av lagstiftningen beträffande mut- och bestickningsbrotten med fokus mot otillbörlighetsrekvisitet

Sveriges självbild som länge varit lyckligt befriad från svågerpolitik, maktmissbruk och pengar under bordet har under det senaste decenniet fått sig en törn. Stora svarta rubriker på löpsedlar har uppmärksammat oss på att korruption och mutor även förekommer i vårt trygga demokratiska samhälle. För att på ett effektivt sätt komma åt detta krävs ett fungerande regelverk, något som haltar då det koThe Swedish Bribery Legislation in use today was written in 1977 and is consequently neither completely modern nor crystal clear. There are no legal definitions on what constitutes a bribe or what is giving rise to corruption and the verdicts are instead made on a case by case basis. The Swedish Bribery Legislation has over the years received a lot of criticism as it is seen as unpredictable and d

Manual for individual-study-plan

Manual för ISP-system_ENG   Introduction to the system This system is somewhat different from the previous one, even if the basic structure is similar. As before, the plan itself consists of a continuous form with open text fields and fields with pre- defined choices. A new feature is that the whole system uses Lucat for login and identification. This means e.g. that you can only access the plans

https://www.science.lu.se/internal/sites/science.lu.se.internal/files/manual_for_individual-study-plan.pdf - 2026-05-09

Severe α1-Antitrypsin Deficiency and Increased Risk of Gastrointestinal Diseases

ObjectiveTo determine whether the genetic disorder severe α1-antitrypsin deficiency, which has a known association with increased risk for development of lung and liver diseases, is also associated with increased risk for development of gastrointestinal diseases.Patients and MethodsWe conducted a national, longitudinal, registry-based study of individuals with severe α1-antitrypsin deficiency (phe

Association of reduced REM sleep with mortality in adults with coronary artery disease and obstructive sleep apnea in the RICCADSA cohort

Purpose: Reduced rapid-eye movement (REM) sleep has been linked to increased mortality in the general population. We investigated whether diminished REM sleep is associated with higher mortality in adults with coronary artery disease (CAD) and obstructive sleep apnea (OSA). Methods: This secondary analysis of the RICCADSA trial included 356 revascularized CAD patients with OSA (apnea–hypopnea inde

Helicobacter pylori, Inflammation, and Long-Term Outcome in Patients With Acute Myocardial Infarction : A Prospective Cohort Study

Background: Helicobacter pylori (Hp) and its virulence factor Cytotoxin-associated gene A (CagA) have been linked to myocardial infarction (MI), but the mechanisms are unknown. This study aims to test if Hp infection and CagA are associated with pre-specified inflammatory and vascular biomarkers in patients with MI and to explore whether a broader biomarker panel can predict infection. Furthermore

It's a Long Walk: Lasting Effects of the Openings of Maternity Wards on Labour Market Performance

Studies showing that large-scale public health interventions in early life have lastingconsequences are still scarce and rarely disclose the mechanisms. In 1931–1946, the Swedishstate reformed the childbirth institutional system that led to the openings of the new maternitywards and to the gradual decline in home deliveries assisted by midwives. Maternity wardsoffered improved conditions for a mot

Advances in the monitoring and forecasting of urban extreme meteorological events : a bibliometric review

Urban meteorology, the study of atmospheric phenomena in urban areas, is vital for understanding the dynamic interactions between rapid urbanization and environmental changes. Over the past two decades (2004–2024), urban heat islands (UHIs), extreme rainfall, pollution, and temperature anomalies have intensified, adversely affecting human health, infrastructure, and ecosystems worldwide. The prese