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Popular Abstract in Swedish Muskulaturen i livmoderns vägg har en uttalad förmåga att dra ihop sig och dessa muskelkontraktioner spelar stor roll vid olika fysiologiska processer t.ex. vid befruktningen och för transport av ägg och spermier. Kontraktionerna i livmodern under förlossning är smärtsamma och benämns följaktligen "värkar". Vid menstruationssmärta är sammandragningar i livmodern också aWith a view to the aetiology and treatment of preterm labour and primary dysmenorrhoea we studied the influence of sexual steroids on the plasma levels of oxytocin and vasopressin, effect of these peptides on uterine contractility in vitro and in vivo, receptor concentrations and antagonists to oxytocin and vasopressin. In postmenopausal women oestrogen increased the concentrations in plasma of bo

We present guidelines on how the solution structure of pi-conjugated hairy-rod polyfluorenes is controlled by the side-chain length and branching. First, the semiquantitative mean-field theory is formulated to predict the phase behavior of the system as a function of side-chain beads (N). The phase transition at N=N* separates a lyotropic phase with solvent coexistence (N < N*) and a metastable me

The aim of this study was to investigate how overall health, participation in physical activities, self-esteem, and social and financial resources are related to life satisfaction among people aged 65 and older with reduced activities of daily living (ADL) capacity in 6 European countries. A subsample of the European Study of Adults’ Well-Being (ESAW), consisting of 2,195 people with reduced ADL c

Popular Abstract in Swedish Bakgrund: Diabetes är en sjukdom som karakteriseras av kroniskt förhöjt blodsocker och som obehandlad kan leda till svåra komplikationer i blodkärl, ögon, njurar, nerver m.m. Sjukdomen beror på kroppens oförmåga att producera (typ 1 diabetes) eller svara på effekt av (typ 2 diabetes) hormonet insulin. Det finns ca 150 miljoner personer med diabetes i världen idag, och sType 2 diabetes is characterised by defects in insulin sensitivity, insulin secretion and increased endogenous glucose production. The relative contribution of each of these defects remains controversial. In order to characterise the metabolic defects in various stages of glucose tolerance, the insulin sensitivity and insulin secretion was measured in a large population based study in Finland and

The ability of many pathogenic microorganisms to cause infection is dependent on their ability to evade attack by the complement system of the host. One mechanism by which microorganisms may avoid complement attack is to bind complement inhibitory molecules present in the host. This thesis describes studies of the complement inhibitor C4BP and of inter-actions between C4BP and the human pathogen

Glucosinolates are natural plant products that function in the defense toward herbivores and pathogens. Plant defense is regulated by multiple signal transduction pathways in which salicylic acid (SA), jasmonic acid, and ethylene function as signaling molecules. Glucosinolate content was analyzed in Arabidopsis wild-type plants in response to single or combinatorial treatments with methyljasmonate

Purpose: To compare the development of intimal hyperplasia after deployment of a self-expanding nitinol stent with and without previous percutaneous transluminal balloon angioplasty (PTA), with the results after PTA alone. Methods: In nine healthy pigs, the iliac arteries were divided into three groups: group 1 (n = 6 arteries) was treated with PTA; group 2 n = 6) with insertion of self-expanding

Citrate synthase (CS) is often used in chaperone assays since this thermosensitive enzyme aggregates at moderately increased temperatures. Small heat shock proteins (sHsps) are molecular chaperones specialized in preventing the aggregation of other proteins, termed substrate proteins, under conditions of transient heat stress. To investigate the mechanism whereby sHsps bind to and stabilize a subs

Objective: To determine whether the polymorphisms in aryl hydrocarbon receptor (AHR), aryl hydrocarbon receptor repressor (AHRR), and aryl hydrocarbon receptor nuclear translocator (ARNT) genes are associated with male factor infertility. Design: An association study. Setting: University research laboratory and andrology clinic. Patient(s): The subjects were infertile Estonian men (n = 112) with a

Background: Genetic factors seem to be of greater importance in prostate cancer than in other forms of cancer. Studies have suggested familial concordance in survival, but the extent to which that is due to tumor characteristics is not known. Objective: We hypothesized that a brother of an index case with prostate cancer is at particularly increased risk of prostate cancer with the same tumor diff

A search is presented for a narrow resonance decaying to a pair of Z bosons using data corresponding to 1.02 fb(-1) of integrated luminosity collected by the ATLAS experiment from pp collisions at root s= 7 TeV. Events containing either four charged leptons (llll) or two charged leptons and two jets (lljj) are analyzed and found to be consistent with the Standard Model background expectation. Lowe

Background: Pathological Q-wave (QW) in the electrocardiogram (ECG) before primary percutaneous coronary intervention (primary PCI) is a strong prognostic marker in patients with ST-segment elevation myocardial infarction (STEMI). However, current binary QW criteria are either not clinically applicable or have a lack of diagnostic performance. Accordingly, we evaluated the association between dura

Hurler syndrome (HS), the most severe phenotype in the spectrum of mucopolysaccharidosis type I, is caused by a deficiency of the lysosomal enzyme alpha-L-iduronidase (IDUA). At present, hematopoietic stem cell transplantation (HSCT) is the only treatment able to prevent disease progression in the central nervous system, and therefore considered the treatment of choice in HS patients. Because IDUA

The partially premixed combustion (PPC) concept is regarded as an intermediate process between the thoroughly mixed Homogeneous charge compression ignition (HCCI) combustion and compression ignition (CI) combustion. It's a combination of auto-ignition mode, a fuel-rich premixed combustion mode, and a diffusion combustion mode. The concept has both high efficiency and low soot emission due to low h

INTRODUCTION: Exercise interventions have a strong evidence base for falls prevention. However, exercise can be challenging to implement and often has limited reach and poor adherence. Digital technology provides opportunities for both increased access to the intervention and support over time. Further knowledge needs to be gained regarding the effectiveness of completely self-managed digital exer

Development, where agriculture is a central component, is today often related to different aspects of sustainability. Sustainable development is argued to be most effective when implemented on a local level where non-governmental organisations (NGOs) are usually active agents. The implementation of sustainable practices, such as sustainable agriculture, could hence be argued to depend upon the eff

Background: High-latitude bird migration has evolved after the last glaciation, in less than 10,000-15,000years. Migrating songbirds rely on an endogenous migratory program, encoding timing, fueling, and routes, but it is still unknown which compass mechanism they use on migration. We used geolocators to track the migration of willow warblers (Phylloscopus trochilus yakutensis) from their eastern

Climate change will alter precipitation patterns with consequences for soil C cycling. An understanding of how fluctuating soil moisture affects microbial processes is therefore critical to predict responses to future global change. We investigated how long-term experimental field drought influences microbial tolerance to lower moisture levels (“resistance”) and ability to recover when rewetted af