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Collagen type II (CII) is a relevant joint-specific autoantigen in the pathogenesis of rheumatoid arthritis (RA). Whereas the reasons for the breakage of self tolerance to this major cartilage component are still enigmatic, T cell responses to glycosylated CII determinants in RA patients indicate that post-translational modifications play a role. Since the conversion of arginine into citrulline by

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This work presents the quantum chemistry package MOLCAS, with emphasis on its usefulness as a platform for developing new quantum chemical codes, and the reader is assumed to be familiar with such a process. The development of new codes for quantum chemistry is a time-consuming job that can be dramatically simplified by using libraries for standard problems (such as calculation of integrals), and

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Economic divisions have deepened in Sweden in recent years, and lone mothers are one group where the poverty rate has increased most (Salonen 2014). At the same time, di erences between the situations of lone mothers have also increased (Lundqvist 2014). As a consequence, intergenerational support from grandparents in terms of care and nancial transfers are important (see also Halleröd 2008). Th

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Purpose: The purpose of the study was to identify serum microRNAs providing a link between male subfertility and metabolic syndrome (MetS) and validate their diagnostic potential. Methods: Sera were analyzed for fertility and MetS-related parameters in subfertile men (n = 79) and controls (n = 38). Literature review identified miR-155-5p, miR-122-5p, miR-200a-3p, and miR-200c-3p which previously w

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To examine and compare the diagnostic accuracy of retinal nerve fibre layer (RNFL) thickness measurements using different Stratus optical coherence tomography (OCT) scanning protocols. Stratus OCT data for 90 healthy subjects and 62 glaucoma patients with mild or moderate visual field loss were prospectively collected and analysed using four RNFL thickness protocols that differed in terms of image

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Outdoor climate has considerable impact on the indoor climate and it is therefore important to adapt the buildings to the climate. This thesis shows how to improve indoor climate in a climate which it is hot, dry in the summer and cold in the winter. My investigative unit is a middle class house in the town Baalbek in Lebanon and the purpose of the study is to come up with proposals on possible so

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Background: Tumour necrosis factor (TNF) antagonists have proved effective as treatment against rheumatoid arthritis ( RA), but the unresolved issue of whether the use of anti-TNF therapy increases the already elevated risk of lymphoma in RA remains a concern. Methods: Using the Swedish Biologics Register (ARTIS), the Swedish Cancer Register, pre-existing RA cohorts and cross-linkage with other na

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Chronic obstructive pulmonary disease (COPD) is associated with colonization by bacterial pathogens and repeated airway infections, leading to exacerbations and impaired lung function. The highly glycosylated mucins in the mucus lining the airways are an important part of the host defense against pathogens. However, mucus accumulation can contribute to COPD pathology. Here, we examined whether inf

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This chapter gives an introduction to the basic structures of Khalkha Mongolian, most of which are similar to those of Mongolian proper in general. Segmental phonology (vowels and consonants) and word structure are analyzed. Major changes from earlier stages of the language are described briefly, as is the writing system, based on the Cyrillic alphabet. Vowel harmony, based on pharyngeality (ATR)

Pågående dödligt våld

Sannolikheten att ett attentat med dödligt våld skulle inträffa på Lunds universitet bedöms vara mycket låg, men om det skulle inträffa är det viktigt att du vet hur du ska agera. Med pågående dödligt våld (PDV) menas en situation där en eller flera gärningspersoner utför våldshandlingar med syfte att skada eller döda så många som möjligt. FlySätt dig själv i säkerhet.Lämna platsen så fort och säk

https://www.medarbetarwebben.lu.se/stod-och-verktyg/sakerhet/pagaende-dodligt-vald - 2026-07-06

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The impact of anaerobic bacteria on the human host is sparsely investigated due to cultivation challenges. Nonetheless, in the last decade increasing research demonstrated the importance of paying attention to these overlooked pathogens. In this chapter, we provide an overview of analyzing surface and intracellular inflammation markers of neutrophils and monocytes in response to Gram-positive anae

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Fluorescence sensing plays an increasingly important role in biology and biomedicine. For many practical applications of fluorescent probes, an “off-on” response is preferred. The question of how fluorescence quenching/enhancement occurs is fundamental and of high importance for application and design of new fluorescent probes. The sensing mechanism of an aminorhodamine (TMARh) pH probe is investi

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Purpose: Paleolithic Diet Fraction (PDF) estimates how large a portion of the absolute dietary intake stems from food groups included in the Paleolithic diet. In randomized controlled trials higher PDFs have been associated with healthier levels of cardiometabolic risk markers. Our aim was to build upon these findings by examining associations between PDF and mortality and incidence of cardiometab

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Objective: To investigate real-world effectiveness of tumor necrosis factor inhibitors (TNFi) in patients with axial spondyloarthritis (axSpA) and the association with (i) treatment line (second and third TNFi-series) and (ii) reason for withdrawal from the preceding TNFi [lack of efficacy (LOE) vs adverse events (AE)]. Methods: Prospectively collected routine care data from 12 European registries

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Objective. The aim was to evaluate cognitive impairments, psychiatric symptoms and cerebral blood flow (CBF) patterns in middle-aged and younger old patients with subjective experience of memory deficits. Methods. The CBF was measured by 99m-Tc-HMPAO-SPECT. The study group was heterogeneous with patients fulfilling criteria for dementia (n=13) and patients with mild cognitive impairment (MCI; n= 2

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Uppsatsen tar sikte på en mycket specifik situation nämligen huruvida eventuella framtida fordringar som är uppkomna ur avtalsgrundade garantiutfästelser är föremål för preklusionsbestämmelsen i 6 § lagen (1981:131) om kallelse på okända borgenärer (”Kallelselagen”). Utredningen har visat att preklusionsbestämmelsen i Kallelselagen ytterst är en avvägning mellan olika intressen som mycket vitt sThis bachelor’s thesis aims at a very specific situation, namely whether any future claims arising from contractual guarantee commitments are subject to the preclusion provision (Sw. preklusionsbestämmelsen) in section 6 of the Notice to Unknown Creditors Act (1981: 131) (the "Notice Act"). The study of the issue herein has shown that the preclusion provision in the Notice Act ultimatel

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I dagens samhälle står ungdomarna inför flera problem i deras liv. För att handskas med dessa väljer ungdomarna olika sätt. Vid vissa tillfällen kan detta leda till att ungdomarna begår oönskade handlingar ur samhällets synpunkt. Genom att söka sig till gäng och därigenom leta efter svar på de problem som de ställs inför leds många ungdomar in i ett asocialt leverne. För att förhindra våra ungdomaIn today's society young people are faced with several problems in their lives. Young people choose different ways to deal with these. At times this can lead to young people committing undesirable actions from the society's point of view. By seeking to gangs and thus looking for the answers to the problems they faced led many young people into an anti-social lifestyle. In order to prevent